Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Climate Change and Fisheries Regulation
Climate change and its effect on marine environment, especially ocean warming, acidification and sea level rise, impacts fisheries in different ways. However, fisheries and climate change are regulated by different international management mechanisms, which makes the current fisheries management system face challenges.
  • 1.4K
  • 03 Sep 2021
Topic Review
Three-finger Toxin
Three-finger toxins (abbreviated 3FTx) are a protein superfamily of small toxin proteins found in the venom of snakes. Three-finger toxins are in turn members of a larger superfamily of three-finger protein domains which includes non-toxic proteins that share a similar protein fold. The group is named for its common structure consisting of three beta strand loops connected to a central core containing four conserved disulfide bonds. The 3FP protein domain has no enzymatic activity and is typically between 60-74 amino acid residues long. Despite their conserved structure, three-finger toxin proteins have a wide range of pharmacological effects. Most members of the family are neurotoxins that act on cholinergic intercellular signaling; the alpha-neurotoxin family interacts with muscle nicotinic acetylcholine receptors (nAChRs), the kappa-bungarotoxin family with neuronal nAChRs, and muscarinic toxins with muscarinic acetylcholine receptors (mAChRs).
  • 1.4K
  • 18 Oct 2022
Topic Review
HMS Lady Nelson (1798)
His Majesty's Armed Survey Vessel Lady Nelson was commissioned in 1799 to survey the coast of Australia. At the time large parts of the Australian coast were unmapped and Britain had claimed only part of the continent. The British Government were concerned that, in the event of settlers of another European power becoming established in Australia, any future conflict in Europe would lead to a widening of the conflict into the southern hemisphere to the detriment of the trade that Britain sought to develop. It was against this background that Lady Nelson was chosen to survey and establish sovereignty over strategic parts of the continent. Lady Nelson left Portsmouth on 18 March 1800 and arrived at Sydney on 16 December 1800 after having been the first vessel to reach the east coast of Australia via Bass Strait. Prior to that date all vessels had sailed around the southern tip of Tasmania to reach their destination. Lady Nelson's survey work commenced shortly after her arrival at Sydney, initially in the Bass Strait area. She was involved in the discovery of Port Phillip, on the coast of Victoria, in establishing settlements on the River Derwent and at Port Dalrymple in Tasmania, at Newcastle and Port Macquarie in New South Wales, and on Melville Island off the north coast of the continent.
  • 1.4K
  • 23 Nov 2022
Biography
Hans Kopfermann
Hans Kopfermann (26 April 1895, in Breckenheim near Wiesbaden – 28 January 1963, in Heidelberg) was a Germany atomic and nuclear physicist. He devoted his entire career to spectroscopic investigations, and he did pioneering work in measuring nuclear spin. During World War II, he worked on the German nuclear energy project, also known as the Uranium Club. Kopfermann began his studies at the
  • 1.4K
  • 29 Nov 2022
Topic Review
Heparan Sulfate Proteoglycans in Tauopathy
Tauopathies are a class of neurodegenerative diseases, including Alzheimer’s disease, and are characterized by intraneuronal tau inclusion in the brain and the patient’s cognitive decline with obscure pathogenesis. Heparan sulfate proteoglycans, a major type of extracellular matrix, have been believed to involve in tauopathies. The heparan sulfate proteoglycans co-deposit with tau in Alzheimer’s patient brain, directly bind to tau and modulate tau secretion, internalization, and aggregation.
  • 1.4K
  • 09 Dec 2022
Topic Review
Computer Vision-Based Wood Identification
The impact of wood identification extends beyond illegal trading and ecological issues. Wood identification is paramount for the timber industry, civil and structural engineering, criminology, archaeology, art history, ethnography, and conservation and restoration, and many other disciplines.
  • 1.4K
  • 15 Dec 2022
Topic Review
Quorum-Sensing Inhibitors from Probiotics
Experience-based knowledge has shown that bacteria can communicate with each other through a cell-density-dependent mechanism called quorum sensing (QS). QS controls specific bacterial phenotypes, such as sporulation, virulence and pathogenesis, the production of degrading enzymes, bioluminescence, swarming motility, and biofilm formation. The expression of these phenotypes in food spoiling and pathogenic bacteria, which may occur in food, can have dramatic consequences on food production, the economy, and health.
  • 1.4K
  • 23 Dec 2022
Topic Review
Control Strategies of the Major Soilborne Fungal/Oomycete Diseases
Globally, tomato is the second most cultivated vegetable crop next to potato, preferentially grown in temperate climates. Processing tomatoes are generally produced in field conditions, in which soilborne pathogens have serious impacts on tomato yield and quality by causing diseases of the tomato root system. Major processing tomato-producing countries have documented soilborne diseases caused by a variety of pathogens including bacteria, fungi, nematodes, and oomycetes, which are of economic importance and may threaten food security. Surveys in the Australian processing tomato industry showed that plant growth and yield were significantly affected by soilborne pathogens, especially Fusarium oxysporum and Pythium species. Globally, different management methods have been used to control diseases such as the use of resistant tomato cultivars, the application of fungicides, and biological control. Among these methods, biocontrol has received increasing attention due to its high efficiency, target-specificity, sustainability and public acceptance. The application of biocontrol is a mix of different strategies, such as applying antagonistic microorganisms to the field, and using the beneficial metabolites synthesized by these microorganisms. 
  • 1.4K
  • 16 Feb 2023
Topic Review
Reis–Bücklers Corneal Dystrophy
Corneal dystrophies are a group of non-inflammatory inherited disorders of the cornea. Reis–Bücklers corneal dystrophy (RBCD) is a bilateral and autosomal dominant disease caused by a mutation in keratoepithilin, i.e., BIGH3, also known as transforming human growth factor (TGFBI), on chromosome 5q.
  • 1.4K
  • 12 Apr 2023
Topic Review
Graph Databases
NoSQL databases were created with the primary goal of addressing the shortcomings in the efficiency of relational databases, and can be of four types: document, column, key-value, and graph databases. Graph databases are designed with a different way of representing and storing data, where data is defined as a collection of nodes and edges. Graph databases can store data and relationships efficiently, and have a flexible and easy to understand data schema. 
  • 1.4K
  • 01 Jun 2023
Topic Review
Fungal Biosynthetic Gene Clusters for Production Secondary Metabolites
Filamentous fungi are one of the most important producers of secondary metabolites. Some of them can have a toxic effect on the human body, leading to diseases. On the other hand, they are widely used as pharmaceutically significant drugs, such as antibiotics, statins, and immunosuppressants. A single fungus species in response to various signals can produce 100 or more secondary metabolites. Such signaling is possible due to the coordinated regulation of several dozen biosynthetic gene clusters (BGCs), which are mosaically localized in different regions of fungal chromosomes.
  • 1.4K
  • 18 Jul 2023
Topic Review
Lightweight IoT Intrusion Detection Systems
Cyber security has become increasingly challenging due to the proliferation of the Internet of Things (IoT), where a massive number of tiny, smart devices push trillion bytes of data to the Internet and is expected to reach 73.1 ZB (zettabytes) by 2025. IoT devices have limited computational capabilities and thus researchers have shifted their focus onto designing lightweight intrusion-detection system (IDS) that can deliver the needed security requirements while operating on those thin devices.
  • 1.4K
  • 29 Aug 2023
Topic Review
Relationship between Academic Challenge Stress and Creativity
Creativity, a multidimensional construct, is commonly defined as the production of novel and useful ideas or solutions. The quality of graduate student cultivation, especially their level of creativity, largely determines the quantity and quality of innovative talents. Therefore, improvement of graduate student creativity is also considered as an important indicator for evaluating the quality of higher education. How to cultivate and stimulate graduate student creativity and thus enhance the innovation capacity and performance of universities has gradually become the focus of universities. However, creativity as an important feature of graduate student performance has received little academic attention.  Studies showed that challenge stress has a positive impact on an individual’s life, work, and personal growth. In addition, challenge stress is a positive stressor that enhances innovation performance.
  • 1.4K
  • 26 Sep 2023
Topic Review
Three-Dimensional Printing Technologies for Oral Films
The interest in buccal drug delivery is under consideration due to some distinct properties compared to the traditional pharmaceutical formulations for oral administration: significantly higher bioavailability, a faster absorption rate of the drug, and substantial compliance for special needs patients. Oral films are obtained through various technologies, from conventional tools to 3D and 4D printing approaches. Three-dimensional printing can solve the formulation problems of producing oral films (OFs).
  • 1.4K
  • 06 Sep 2023
Topic Review
Additively Manufactured Polylactic Acid in Dentistry
Additive manufacturing (AM), which is also called rapid prototyping/3D printing/layered manufacturing, can be considered as a rapid conversion between digital and physical models. One of the most used materials in AM is polylactic acid (PLA), which has advantageous material properties such as biocompatibility, biodegradability, and nontoxicity. For many medical applications, it is considered as a leading biomaterial. In dentistry, in addition to its uses in dental models (education, teaching, simulation needs), it can be used for therapeutic objectives and tissue engineering.
  • 1.4K
  • 28 Jun 2023
Topic Review
Leukaemic Stem Cells
Hematopoietic stem cells ‘choose’ a cell lineage from all options to develop towards a mature blood cell type and they are a mixture of cells with different lineage signatures. However, hematopoietic stem cells and their progeny retain enough versatility to ‘step sideways’ into a different pathway. Most, if not all cancers, arise from tissue-specific stem cells that have accumulated oncogenic insults to their genome and epigenome. We believe that the first oncogenic insult to a normal hematopoietic stem cell restricts the resulting leukaemia stem cell and its progeny to a single pathway. We hypothesized this from studies of transgenic mice in which we restricted oncogene expression to hematopoietic stem cells, via the Sca-1 promotor, and this led to lineage-restricted leukaemias.
  • 1.4K
  • 30 Oct 2020
Topic Review
Electrospinning in GBR
Nanofibre-based membranes or scaffolds exhibit high surface-to-volume ratio, which allows an improved cell adhesion, representing an attractive subgroup of biomaterials due to their unique properties. Guided bone regeneration is a surgical procedure in which bone regeneration, due to bone atrophy following tooth loss, is “guided” by an occlusive barrier. New approaches such as multifunctional multilayering and coupling with bone promoting factors or antimicrobial agents, makes this technology very attractive also for bone regeneration procedures. The technical limitations of traditional electrospinning strategies for bone-tissue engineering applications might be critical for the preparation of three-dimensional scaffolds.  
  • 1.4K
  • 30 Oct 2020
Topic Review
Lightweight Proof of Game (LPoG)
Interoperability is widely adopted in the case of cross-departmental or specialization cases. As the human body demands multiple specialized and cross-disciplined medical experiments, interoperability of business entities like different departments, different specializations, the involvement of legal and government monitoring issues etc. are not sufficient to reduce the active medical cases. A patient-centric system with high capability to collect, retrieve, store or exchange data is the demand for present and future times. Such data-centric health processes would bring automated patient medication, or patient self-driven trusted and high satisfaction capabilities. However, data-centric processes are having a huge set of challenges such as security, technology, governance, adoption, deployment, integration etc. This work has explored the feasibility to integrate resource-constrained devices-based wearable kidney systems in the Industry 4.0 network and facilitates data collection, liquidity, storage, retrieval and exchange systems. Thereafter, a Healthcare 4.0 processes-based wearable kidney system is proposed that is having the blockchain technology advantages. Further, game theory-based consensus algorithms are proposed for resource-constrained devices in the kidney system. The overall system design would bring an example for the transition from the specialization or departmental-centric approach to data and patient-centric approach that would bring more transparency, trust and healthy practices in the healthcare sector. Results show a variation of 0.10 million GH/s to 0.18 million GH/s hash rate for the proposed approach. The chances of a majority attack in the proposed scheme are statistically proved to be minimum. Further Average Packet Delivery Rate (ADPR) lies between 95% to 97%, approximately, without the presence of outliers. In the presence of outliers, network performance decreases below 80% APDR (to a minimum of 41.3%) and this indicates that there are outliers present in the network. Simulation results show that the Average Throughput (AT) value lies between 120 Kbps to 250 Kbps.
  • 1.4K
  • 29 Oct 2020
Topic Review
Aquaporins
Enhancement of the passage of water through membranes is one of the main mechanisms via which cells can maintain their homeostasis under stress conditions, and aquaporins are the main participants in this process. However, in the last few years, a number of studies have reported discrepancies between aquaporin messenger RNA (mRNA) expression and the number of aquaporin proteins synthesised in response to abiotic stress. These observations suggest the existence of post-transcriptional mechanisms which regulate plasma membrane intrinsic protein (PIP) trafficking to the plasma membrane. This indicates that the mRNA synthesis of some aquaporins could be modulated by the accumulation of the corresponding encoded protein, in relation to the turnover of the membranes. 
  • 1.4K
  • 11 Dec 2020
Topic Review
Neonatal Hypoxic-Ischemic Encephalopathy
Neonatal hypoxic-ischemic encephalopathy (HIE) is an important cause of mortality and morbidity in the perinatal period. This condition results from a period of ischemia and hypoxia to the brain of neonates, leading to several disorders that profoundly affect the daily life of patients and their families. Currently, therapeutic hypothermia (TH) is the standard of care in developing countries; however, TH is not always effective, especially in severe cases of HIE. Addressing this concern, several preclinical studies assessed the potential of stem cell therapy (SCT) for HIE.
  • 1.4K
  • 12 Apr 2021
  • Page
  • of
  • 2800
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback