Electrospun nanofiber biomaterials

Created by: Bo Liu

Electrospinning is a simple, low-cost, and versatile technique to fabricate long and continuous ultrafine nanofibers by jetting a charged polymer solution or a melt in a high voltage electrostatic field. The diameter of nanofibers can range from a few nanometers to a few micrometers. Electrospun nanofiber materials not only have the advantages of large surface area, high aspect ratio, ultrahigh porosity, and excellent uniformity, but also have the advantages of good biocompatibility such as good bioabsorbability and selective permeability. These advantages are conducive to wound healing, skin regeneration, and the preparation of the excellent bionic structure performance. Furthermore, depending on the organism's requirements of the materials’ structures and the biological characteristics, the nanofibers of different compositions, topographies, structures and functionalities can be designed and manufactured by adjusting the electrospinning parameters. Electrospun nanofiber materials have high potential applications in the field of biomedicine, such as filtration membrane, separation membrane, tissue engineering scaffold, wound dressing, drug delivery and its’ controlled release. Therefore, electrospinning technology can be potentially used in biomedical materials.

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This topical collection on ' Electrospun Biomedicine' aims to cover the above-mentioned aspects regarding biomedical nanofiber materials fabricated by electrospinning. Key issues are addressed to give an overview of the recent fundamental and applied research. Topics covered are:

l Tissue engineering scaffolds/medical prostheses

l Tissue template

l Wound dressing

l Drug release and drug delivery

l Pharmaceutical composition

l Medical masks

l Non-woven bandage

l Biopolymer fiber shell