This video explores the latest scientific understanding of platelet-rich plasma (PRP) therapy, a cutting-edge treatment increasingly used in both cosmetic and orthopedic medicine. Drawing from a comprehensive analysis of 75 clinical trials involving over 5,700 patients worldwide, the presentation reveals crucial insights about PRP preparation techniques and their impact on treatment outcomes. Viewers will discover how variations in centrifugation methods, platelet concentration levels, and temperature control significantly affect PRP's effectiveness, with research showing proper temperature maintenance can improve outcomes by up to 79%. The video introduces an innovative quality assessment tool - the William-Eqram Scoring System for PRP Quality Reporting (WESS-PQR) - developed to standardize PRP protocols across clinics and research institutions. Through clear visual explanations, we demonstrate why consistent preparation methods and stronger regulatory standards are essential for ensuring patient safety and treatment reliability in this rapidly growing field of regenerative medicine.