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Topic review
Updated time: 14 Apr 2021
Submitted by: Fabienne Jordana
Definition: The three-dimensional printing of scaffolds is an interesting alternative to the traditional techniques of periodontal regeneration. This technique uses computer assisted design and manufacturing after CT scan. After 3D modelling, individualized scaffolds are printed by extrusion, selective laser sintering, stereolithography, or powder bed inkjet printing. These scaffolds can be made of one or several materials such as natural polymers, synthetic polymers, or bioceramics.
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Topic review
Updated time: 09 Apr 2021
Submitted by: Mika Salmi
Definition: Additive manufacturing (AM, 3D printing) is used in many fields and different industries. In the medical and dental field, every patient is unique and, therefore, AM has significant potential in personalized and customized solutions. This text explores what additive manufacturing processes and materials are utilized in medical and dental applications, especially focusing on processes that are less commonly used. The processes are categorized in ISO/ASTM process classes: powder bed fusion, material extrusion, VAT photopolymerization, material jetting, binder jetting, sheet lamination and directed energy deposition combined with classification of medical applications of AM. Based on the findings, it seems that directed energy deposition is utilized rarely only in implants and sheet lamination rarely for medical models or phantoms. Powder bed fusion, material extrusion and VAT photopolymerization are utilized in all categories. Material jetting is not used for implants and biomanufacturing, and binder jetting is not utilized for tools, instruments and parts for medical devices. The most common materials are thermoplastics, photopolymers and metals such as titanium alloys. If standard terminology of AM would be followed, this would allow a more systematic review of the utilization of different AM processes.
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Topic review
Updated time: 11 Oct 2021
Submitted by: Antonino Fiorino
Definition: Amelogenins are enamel matrix proteins currently used to treat bone defects in periodontal surgery. Recent studies have highlighted the relevance of amelogenin-derived peptides, named LRAP, TRAP, SP, and C11, in bone tissue engineering. Interestingly, these peptides seem to maintain or even improve the biological activity of the full-length protein, which has received attention in the field of bone regeneration.
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Topic review
Updated time: 27 Apr 2021
Submitted by: Mladen Korbelik
Definition: Anti-tumor photodynamic therapy (PDT) is a unique oxidative stress-based modality that has proven highly effective on a variety of solid malignancies. Endogenous nitric oxide (NO) has a critical role in the therapeutic outcome of this modality.
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Topic review
Updated time: 13 Jan 2021
Submitted by: Xiao-Chuan Fan
Definition: In order to determine the correlation between the inclination of articular eminence (AEI) and the development of temporomandibular disorders (TMDs), a systematic review was performed.
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Topic review
Updated time: 25 Apr 2021
Submitted by: Gianrico Spagnuolo
Definition: Over 65 components detected in oral fluid have been examined as possible markers for the progression of periodontitis.
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Topic review
Updated time: 23 Jun 2021
Submitted by: Babak Saravi
Definition: CAD/CAM ceramics present a promising alternative to metal-ceramic fixed dental prostheses.
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Topic review
Updated time: 23 Aug 2021
Submitted by: PALLAVI TONSEKAR
Definition: The aim of the article is to discuss the development of calcium channel blocker (CCB) influenced gingival enlargement.
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Topic review
Updated time: 23 Feb 2021
Submitted by: Soo-min Ok
Definition: Candida species are common global opportunistic pathogens that could repeatedly and chronically cause oral mucosa infection and create an inflammatory environment, leading to organ dysfunction. Oral Candida infections may cause temporary or permanent damage to salivary glands, resulting in the destruction of acinar cells and the formation of scar tissue. Restricted function of the salivary glands leads to discomfort and diseases of the oral mucosa, such as dry mouth and associated infection.
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Topic review
Updated time: 23 Sep 2021
Submitted by: Iole Vozza
Definition: Cleft lip and palate (CLP) are craniofacial dysmorphisms that fall within the anomalies of the developmental jaws as they are congenital malformations characterized by the arrested development of the homonymous regions of the maxillofacial district. Orofacial clefts occur due to failure of migration or fusion in the embryonic period of intrauterine life; craniofacial skeletal structures, hard and soft tissues of the oral cavity are particularly involved. The cause of cleft lip and/or palate (CLP) is thought to be multifactorial, namely through genetic or environmental factors.
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