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Topic Review
Physico-Chemical Properties of Sodium Alginate
The macromolecules of natural origin have attracted the attention of many researchers as essential to protect the structures of unstable drug substances. After analyzing the studies carried out by various authors, researchers found that these molecules are used for both investigational and therapeutic purposes. This requires the design of certain drug delivery formulations knowing the nature of the macromolecule, its target organ, the required dose and the route of delivery. Therefore, researchers consider it important to use sodium alginate to optimize the delivery of drug substances for maximum therapeutic performance in the body after administration.
  • 8.9K
  • 19 Oct 2022
Topic Review
Parasocial Relationships
A parasocial relationship (PSR) is a one-sided relationship that media users form as a result of exposure to media personas. In 1956, the term parasocial relationship was coined by Donald Horton and R. Richard Wohl. They focused on the psychological attachment that was formed from viewing television personalities. Their work laid the foundation and popularized a wide range of research on parasocial phenomena. A parasocial interaction, an exposure that garners interest in a persona, becomes a parasocial relationship after repeated exposure to the media persona causes the media users to develop illusions of intimacy, friendship, and identification. Positive information learned about the media persona results in increased attraction and the relationship progresses. Parasocial relationships are enhanced due to trust and self-disclosure provided by the media persona. Media users are loyal and feel directly connected to the persona much like their close friends by observing and interpreting their appearance, gestures, voice, conversation, and conduct. Media personas have a significant amount of influence over media users, positive or negative, informing the way that they perceive certain topics or even their purchasing habits. Social media introduces additional opportunities for parasocial relationships to intensify because it provides more opportunities for intimate, reciprocal, and frequent interactions between the user and persona.
  • 8.9K
  • 24 Nov 2022
Topic Review
Subject–object–verb
In linguistic typology, a subject–object–verb (SOV) language is one in which the subject, object, and verb of a sentence always or usually appear in that order. If English were SOV, "Sam oranges ate" would be an ordinary sentence, as opposed to the actual Standard English "Sam ate oranges" which is subject–verb–object (SVO). The term is often loosely used for ergative languages like Adyghe and Basque that really have agents instead of subjects.
  • 8.9K
  • 27 Oct 2022
Topic Review
Importance, Properties and Benefits of Biochar
Biochar can be defined as the carbonaceous product that is obtained when biomass is subjected to heat treatment in an oxygen-limited environment (pyrolysis) and the charred product when applied to soil as an amendment. It is an important and popular carbon sequestration method to mitigate climate change.
  • 8.9K
  • 15 Jun 2022
Topic Review
Closed Timelike Curves
Closed timelike curves (CTCs) are space-time trajectories that return to their starting point without violating the laws of special relativity. A traveler along a CTC could journey into the future but arrive in its past, creating a possible violation of the principle of causality. Such CTCs occur in Gödel’s rotating universe and many other general relativistic solutions of classical Einstein’s field equations. The chronological protection conjecture suggests that Nature forbids this kind of situation.
  • 8.9K
  • 27 Jan 2021
Topic Review
Stonefish: venom components, pathology, distribution
There are five species of stonefish within the genus Synanceia: Synanceia horrida (previously referred to as S. trachynis), S. verrucosa, S. alula, S. nana and S. platyrhyncha. Synanceia spp. can grow 35–50 cm in length and have evolved grey and mottled skin to camouflage themselves amongst encrusted rocks and coral for predation and defense. Synanceia species have up to 15 dorsal fin spines that are erected when the fish is disturbed. Stings from this medically important group of fish are known to cause painful and lethal human envenomations. Stonefish are regarded as one of the most venomous fish in the world. Research on stonefish venom has chiefly focused on the in vitro and in vivo neurological, cardiovascular, cytotoxic and nociceptive effects of the venom.
  • 8.9K
  • 17 Jun 2021
Topic Review
Dialysis (Biochemistry)
In biochemistry, dialysis is the process of separating molecules in solution by the difference in their rates of diffusion through a semipermeable membrane, such as dialysis tubing. Dialysis is a common laboratory technique that operates on the same principle as medical dialysis. In the context of life science research, the most common application of dialysis is for the removal of unwanted small molecules such as salts, reducing agents, or dyes from larger macromolecules such as proteins, DNA, or polysaccharides. Dialysis is also commonly used for buffer exchange and drug binding studies. The concept of dialysis was introduced in 1861 by the Scottish chemist Thomas Graham. He used this technique to separate sucrose (small molecule) and gum Arabic solutes (large molecule) in aqueous solution. He called the diffusible solutes crystalloids and those that would not pass the membrane colloids. From this concept dialysis can be defined as a spontaneous separation process of suspended colloidal particles from dissolved ions or molecules of small dimensions through a semi permeable membrane. Most common dialysis membrane are made of cellulose, modified cellulose or synthetic polymer (cellulose acetate or nitrocellulose).
  • 8.9K
  • 07 Nov 2022
Topic Review
Misogyny in Horror Films
Misogyny can occur in horror films when there is a degrading representation of women. This is found particularly in slasher films, where there is often gendered specific violence towards women. Female characters experience violence and brutality at the hands of male antagonists far more often than male characters in these films. Female characters are likely to experience sexual violence, particularly in the rape-and-revenge subgenre.
  • 8.9K
  • 28 Nov 2022
Topic Review
Mechanisms of anticoagulant drugs
Anticoagulant drugs have been used to prevent and treat thrombosis. However, they are associated with risk of hemorrhage. Therefore, prior to their clinical use, it is important to assess the risk of bleeding and thrombosis. In case of older anticoagulant drugs like heparin and warfarin, dose adjustment is required owing to narrow therapeutic ranges. The established monitoring methods for heparin and warfarin are activated partial thromboplastin time (APTT)/anti-Xa assay and prothrombin time – international normalized ratio (PT-INR), respectively. Since 2008, new generation anticoagulant drugs, called direct oral anticoagulants (DOACs), have been widely prescribed to prevent and treat several thromboembolic diseases. Although the use of DOACs without routine monitoring and frequent dose adjustment has been shown to be safe and effective, there may be clinical circumstances in specific patients when measurement of the anticoagulant effects of DOACs is required. Recently, anticoagulation therapy has received attention when treating patients with coronavirus disease 2019 (COVID-19).
  • 8.8K
  • 23 Feb 2023
Topic Review
Agricultural Expansion Drivers and Constraints
Agricultural expansion refers to the conversion of uncultivated land, including natural forests, woodlands, grasslands and wetlands into crop or grazing land, and may be undertaken by smallholders or largescale farmers. 
  • 8.8K
  • 30 Apr 2021
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