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Topic Review
12-Lipoxygenases
Lipoxygenases (LOXs) are lipid metabolizing enzymes that catalyze the di-oxygenation of polyunsaturated fatty acids to generate active eicosanoid products. 12-lipoxygenases (12-LOXs) primarily oxygenate the 12th carbon of its substrates. 
  • 689
  • 26 Aug 2021
Topic Review
121-PDS-ihpRNA-mediated silencing of PDS gene
Long introm-spliced hairpin RNA (ihpRNA) constructs which contained inverted repeats of the phytoene desaturase (PDS) separated by an intron, had been shown to very effective in triggering PDS silencing in Brassica napus. Using the PDS gene as a target control, it was shown that the RCA-mediated long ihpRNA construct was signicantly effective in triggering gene silence in B. napus.
  • 742
  • 26 Aug 2021
Topic Review
130–30 Fund
A 130–30 fund or a ratio up to 150/50 is a type of collective investment vehicle, often a type of specialty mutual fund, but which allows the fund manager simultaneously to hold both long and short positions on different equities in the fund. Traditionally, mutual funds were long-only investments. 130–30 funds are a fast-growing segment of the financial industry; they should be available both as traditional mutual funds, and as exchange-traded funds (ETFs). While this type of investment has existed for a while in the hedge fund industry, its availability for retail investors is relatively new. A 130–30 fund is considered a long-short equity fund, meaning it goes both long and short at the same time. The "130" portion stands for 130% exposure to its long portfolio and the "30" portion stands for 30% exposure to its short portfolio. The structure usually ranges from 120–20 up to 150–50 with 130–30 being the most popular and is limited to 150/50 because of Reg T limiting the short side to 50%.
  • 452
  • 04 Nov 2022
Topic Review
14-3-3σ and Its Modulators
14-3-3σ is an acidic homodimer protein with more than one hundred different protein partners associated with oncogenic signaling and cell cycle regulation. 
  • 781
  • 18 May 2021
Topic Review
15 Minute City
The 15-minute city is a residential urban concept in which all city residents are able to meet most of their needs within a short walk or bicycle ride from their homes. The concept was popularized by Mayor Anne Hidalgo of Paris, who was in turn inspired by French-Colombian scientist Carlos Moreno. It has been described as a "return to a local way of life. 15-minute cities are built from a series of 15-minute neighborhoods, also known as complete communities or walkable neighborhoods.
  • 1.2K
  • 15 Nov 2022
Topic Review
15q13.3 Microdeletion
15q13.3 microdeletion is a chromosomal change in which a small piece of chromosome 15 is deleted in each cell. The deletion occurs on the long (q) arm of the chromosome at a position designated q13.3. This chromosomal change increases the risk of intellectual disability, seizures, behavioral problems, and psychiatric disorders. However, some people with a 15q13.3 microdeletion do not appear to have any associated features.  
  • 1.0K
  • 26 Aug 2021
Topic Review
15q24 Microdeletion
15q24 microdeletion is a chromosomal change in which a small piece of chromosome 15 is deleted in each cell. The deletion occurs on the long (q) arm of the chromosome at a position designated q24.
  • 666
  • 26 Aug 2021
Topic Review
16:9
16:9 (1.77:1) (16:9 = 42:32) is an aspect ratio with a width of 16 units and height of 9. Since 2010 it has become the most common aspect ratio for televisions and computer monitors, and is also the international standard format of HDTV, Full HD, non-HD digital television and analog widescreen television. This has replaced the old 4:3 aspect ratio.
  • 937
  • 27 Oct 2022
Topic Review
16p11.2 deletion syndrome
16p11.2 deletion syndrome is a disorder caused by a deletion of a small piece of chromosome 16. The deletion occurs near the middle of the chromosome at a location designated p11.2.  
  • 677
  • 10 Apr 2021
Topic Review
16p11.2 Duplication
16p11.2 duplication is a chromosomal change in which a small amount of genetic material within chromosome 16 is abnormally copied (duplicated). The duplication occurs near the middle of the chromosome at a location designated p11.2. This duplication can have a variety of effects. Common characteristics that occur in people with a 16p11.2 duplication include a low weight; a small head size (microcephaly); and developmental delay, especially in speech and language. Affected individuals also have an increased risk of behavioral problems. However, some people with the duplication have no identified physical or behavioral abnormalities.
  • 846
  • 23 Dec 2020
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