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Topic Review
Two-Faced Role of TANs in Tumor Progression
Tumor-associated neutrophils (TANs) may differentiate into different patterns under the stimulation of different factors, and they play a dual role in the occurrence and progression of tumors in direct or indirect ways.
  • 480
  • 25 Nov 2022
Topic Review
Two-Dimensional Transillumination Imaging and Functional Imaging
Imaging within the realm of biomedical applications can be categorized into two domains based on object size: macroscopic and microscopic imaging. The substantive importance of macroscopic imaging has been demonstrated prominently in medical practices, encompassing X-ray imaging, positron emission tomography (PET), magnetic resonance imaging (MRI), and ultrasonic echo imaging. Although these modalities offer undeniable utility, they are not devoid of limitations. Even with recent progress in X-ray detection, the ionizing radiation inherent to X-ray imaging engenders challenges related to repeated exposure. Similarly, the utilization of PET and MRI is impeded by the considerable scale of the necessary apparatus, thereby hindering seamless bedside deployment. The domain of ultrasound imaging presents difficulty involving a tradeoff between spatial resolution and penetration depth in animal bodies. An additional contender for noninvasive macroscopic structural imaging of animal bodies has emerged: optical imaging.
  • 242
  • 01 Nov 2023
Topic Review
Two-Dimensional Theranostic Nanomaterials in Cancer
As the combination of therapies enhances the performance of biocompatible materials in cancer treatment, theranostic therapies are attracting increasing attention rather than individual approaches.
  • 660
  • 18 Feb 2021
Topic Review
Two-Dimensional Space
Two-dimensional space (also known as 2D space, 2-space, or bi-dimensional space) is a geometric setting in which two values (called parameters) are required to determine the position of an element (i.e., point). The set [math]\displaystyle{ \mathbb{R}^2 }[/math] of pairs of real numbers with appropriate structure often serves as the canonical example of a two-dimensional Euclidean space. For a generalization of the concept, see dimension. Two-dimensional space can be seen as a projection of the physical universe onto a plane. Usually, it is thought of as a Euclidean space and the two dimensions are called length and width.
  • 4.7K
  • 28 Nov 2022
Topic Review
Two-Dimensional Silicon Carbide
Two-dimensional silicon carbide (2D SiC) is a single/few atomic layer of silicon carbide.   2D SiC has a graphene-like honeycomb structure consisting of alternating Si and C atoms. In the monolayer SiC, the C and Si atoms bond through  sp2 hybridization to form the SiC sheet.  As a direct wide bandgap semiconducting material, 2D SiC has the potential to bring revolutionary advances into power electronics, optoelectronic and other SiC-based devices. It can overcome current limitations with silicon, bulk SiC, and gapless graphene. In addition to SiC, which is the most stable form of monolayer silicon carbide, other compositions, i.e. SixCy, are also predicted to be energetically favorable. Depending on the stoichiometry and bonding, monolayer SixCy may behave as a semiconductor, semimetal or topological insulator. With different Si/C ratios, the emerging 2D silicon carbide materials could attain novel electronic, optical, magnetic, mechanical, and chemical properties that go beyond those of graphene, silicene, and already discovered 2D semiconducting materials.
  • 4.1K
  • 08 May 2022
Topic Review
Two-Dimensional Quantum Billiards
Two-dimensional quantum billiards are one of the most important paradigms for exploring the connection between quantum and classical worlds. Researchers are mainly focused on nonintegrable and irregular shapes to understand the quantum characteristics of chaotic billiards. The emergence of the scarred modes relevant to unstable periodic orbits (POs) is one intriguing finding in nonintegrable quantum billiards. On the other hand, stable POs are abundant in integrable billiards. The quantum wavefunctions associated with stable POs have been shown to play a key role in ballistic transport. 
  • 465
  • 19 Oct 2023
Topic Review
Two-Dimensional Nanostructures as Surface-Enhanced Raman Scattering Substrates
Two-dimensional nanostructures (2DNS) attract tremendous interest and have emerged as potential materials for a variety of applications, including biomolecule sensing, due to their high surface-to-volume ratio, tuneable optical and electronic properties. Advancements in the engineering of 2DNS and associated technologies have opened up new opportunities. Surface-enhanced Raman scattering (SERS) is a rapid, highly sensitive, non-destructive analytical technique with exceptional signal amplification potential. Several structurally and chemically engineered 2DNS with added advantages (e.g., π–π* interaction), over plasmonic SERS substrates, have been developed specifically towards biomolecule sensing in a complex matrix, such as biological fluids. 
  • 538
  • 11 Jan 2023
Topic Review
Two-Dimensional Nanomaterials in Organic Solar Cells
The thin-film organic solar cells (OSCs) are currently one of the most promising photovoltaic technologies to effectively harvest the solar energy due to their attractive features of mechanical flexibility, light weight, low-cost manufacturing, and solution-processed large-scale fabrication, etc. However, the relative insufficient light absorption, short exciton diffusion distance, and low carrier mobility of the OSCs determine the power conversion efficiency (PCE) of the devices are relatively lower than their inorganic photovoltaic counterparts. To conquer the challenges, the two-dimensional (2D) nanomaterials, which have excellent photoelectric properties, tunable energy band structure, and solvent compatibility etc., exhibit the great potential to enhance the performance of the OSCs.
  • 778
  • 19 Apr 2022
Topic Review
Two-Dimensional Nanomaterials for Biomedical Applications
Two-dimensional nanomaterials (2DNMs) received remarkable attention in nanomedicine as a class of new nanomaterials in recent years. 2DNMs, which range from nanometer to micrometer scales, have one or a few atomic thicknesses and are one of the most promising materials for biomedical applications owing to their special structure and unique properties.
  • 710
  • 01 Apr 2022
Topic Review
Two-Dimensional Nanomaterials
Two-dimensional (2D) nanomaterials have attracted increased interest and exhibited extended applications from nanotechnology to materials science, biomedicine, tissue engineering, as well as energy storage and environmental science. With the development of the synthesis and fabrication of 2D materials, a new family of 2D materials, metal carbides (MCs), revealed promising applications in recent years, and have been utilized for the fabrication of various functional 2D and three-dimensional (3D) nanomaterials for energy and environmental applications, ascribing to the unique physical and chemical properties of MCs. In this review, we present recent advance in the synthesis, fabrication, and applications of 2D and 3D MC-based nanomaterials. This work provides useful information on the preparation, hybridization, structural tailoring, and applications of MC-based materials, and is expected to inspire the design and fabrication of novel and functional MXene materials with improved performance.
  • 1.5K
  • 08 Feb 2021
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