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Topic Review
Nectria pseudotrichia Associated with Camellia Canker Disease
Camellia japonica is a native tree species with high economic value that is widely cultivated in southern China. Canker disease was a serious threat to the growth of camellia trees. However, the pathogen causing this disease in China has not yet been reported. 
  • 365
  • 01 Aug 2023
Topic Review
Neisseria gonorrhoeae Antimicrobial Resistance
The growing threat of antibiotic-resistant Neisseria gonorrhoeae, which causes gonorrhea, presents a current public health challenge. Over the years, the pathogen has developed resistance to different antibiotics, leaving few effective treatment options. High-level resistance to key drugs, including ceftriaxone, has become a concerning reality.
  • 171
  • 05 Jan 2024
Topic Review
NORAD-Regulated Signaling Pathways in Breast Cancer Progression
Breast cancer (BC) is a heterogeneous disease classified into different subtypes presenting several treatment challenges, especially in more advanced cases arising from triple negative breast cancer. NORAD is a long non-coding RNA (lncRNA) activated by DNA damage, with an impacting role in the repair process of DNA insults. This lncRNA is differentially expressed in BC subtypes, participating in cancer initiation and progression, by interacting with an extended range of signaling partners.
  • 135
  • 20 Feb 2024
Topic Review
Nrf2 in Neurogenesis and Disease Development
Neurogenesis occurs in the brain during embryonic development and throughout adulthood. Neurogenesis occurs in the hippocampus and under normal conditions and persists in two regions of the brain—the subgranular zone (SGZ) in the dentate gyrus of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles. The transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) is a major regulator of metabolism, protein quality control, and antioxidative defense, and is linked to neurogenesis. 
  • 750
  • 13 Jul 2022
Topic Review
O-GlcNAcylation Regulate Skeletal Muscle
O-GlcNAcylation is a highly dynamic, reversible and atypical glycosylation that regulates the activity, biological function, stability, sublocation and interaction of target proteins. O-GlcNAcylation receives and coordinates different signal inputs as an intracellular integrator similar to the nutrient sensor and stress receptor, which target multiple substrates with spatio-temporal analysis specifically to maintain cellular homeostasis and normal physiological functions.
  • 669
  • 13 Jun 2022
Topic Review
Ocimum Species
Ocimum is known to be one of the medicinal plants that have been used traditionally by local people. This plant contains components of secondary metabolites such as phenolics, flavonoids, steroids, terpenoids, and alkaloids.
  • 693
  • 31 Oct 2022
Topic Review
Opuntia ficus-indica (L.) Mill Species
Opuntia ficus-indica (L.) Mill. (OFI) belongs to the Cactaceae family, which contains about 130 genera and nearly 1600 species. This plant is originally from South America, namely Mexico, and can be found in the Middle East, South Africa, India, Australia, and some Mediterranean countries.
  • 730
  • 26 Apr 2023
Topic Review
Origanum majorana Essential Oil—Chemistry and Pesticide Activity
Origanum majorana is a medicinal and aromatic plant that belongs to the Lamiaceae family. It is cultivated in several parts of the world and, due to its splendid aroma and taste, is widely used for culinary purposes and in perfumes. The essential oil of the plant, to which is attributed its aroma, contains many secondary metabolites with valuable biological activity. One of them is the pesticide activity, which has attracted much interest. Given the necessity of replacing synthetic pesticides, essential oils are studied in an attempt to find naturally derived products.
  • 616
  • 09 Dec 2022
Topic Review
P. ginseng in Reactive Oxygen Species-Mediated Diseases
Reactive oxygen species (ROS)-the byproduct of regular cell activity formed by various cellular components—play a significant role in pathological and physiological conditions. Alternatively, antioxidants are compounds that reduce or scavenge reactive species in cells. An asymmetry between the antioxidant defense system and ROS from intracellular and extracellular sources cause chronic diseases such as cancer, inflammation, tumorigenesis, cardiovascular and neurogenerative diseases. P. ginseng and its derivatives are some of the antioxidant-rich sources involved in the regulation of many oxidative-stress-related pathways.
  • 515
  • 13 Mar 2023
Topic Review
P. falciparum Invasion and Erythrocyte Aging
Plasmodium parasites need to find red blood cells (RBCs) that, on the one hand, expose receptors for the pathogen ligands and, on the other hand, maintain the right geometry to facilitate merozoite attachment and entry into the red blood cell. Both characteristics change with the maturation of erythrocytes. 
  • 108
  • 28 Feb 2024
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