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Topic Review
Use of Insect Meal for Poultry Diets
Interest has grown among poultry nutritionists in using alternative protein sources, such as insect meal, to meet the protein requirements of poultry due to sustainability concerns surrounding traditional protein sources such as soybean and fish meal. Insect meal can be produced from different insects, including black soldier fly, mealworms, and house crickets, and its nutrient composition varies depending on the insect species, the substrate they are reared on, and the production method. Insect meal has been shown to be a rich source of protein, amino acids (lysine, methionine), and minerals (calcium, phosphorus, zinc), with a high digestibility rate, making it a valuable feed ingredient for poultry production. Additionally, using insect meal in poultry feed could reduce the cost of production and the environmental impact on the industry. Furthermore, the use of insect meal has the potential to improve the growth performance and meat quality of poultry species.
  • 432
  • 26 Jun 2023
Topic Review
Use of Immune Regulation in HNSCC
Immunotherapy has emerged as a promising new treatment modality for head and neck cancer, offering the potential for targeted and effective cancer management. Squamous cell carcinomas pose significant challenges due to their aggressive nature and limited treatment options. Conventional therapies such as surgery, radiation, and chemotherapy often have limited success rates and can have significant side effects. Immunotherapy harnesses the power of the immune system to recognize and eliminate cancer cells, and thus represents a novel approach with the potential to improve patient outcomes. In the management of head and neck squamous cell carcinoma (HNSCC), important contributions are made by immunotherapies, including adaptive cell therapy (ACT) and immune checkpoint inhibitor therapy.
  • 271
  • 12 Mar 2024
Topic Review
Use of Herbal Dietary Supplements in the USA
Herbal and dietary supplement (HDS) use has grown exponentially in the United States. Unfortunately, the incidence of HDS-related liver injury has proportionally increased. Despite the potential for certain HDSs to cause clinically significant liver injury, they are not regulated by the Food and Drug Administration. The efforts have been made to regulate HDSs but are far removed from the scrutiny of prescription medications. Scant literature exists on HDSs and their risks of causing liver injury.
  • 452
  • 19 Aug 2022
Topic Review
Use of Green Antimicrobials in Diabetic Foot Ulcers
Diabetic foot ulcers (DFU) are one of the most serious and devastating complications of diabetes and account for a significant decrease in quality of life and costly healthcare expenses worldwide. This condition affects around 15% of diabetic patients and is one of the leading causes of lower limb amputations. DFUs generally present poor clinical outcomes, mainly due to the impaired healing process and the elevated risk of microbial infections which leads to tissue damage. Antimicrobial resistance poses a rising threat to global health, thus hampering DFU treatment and care. Faced with this reality, it is pivotal to find greener and less environmentally impactful alternatives for fighting these resistant microbes. Antimicrobial peptides are small molecules that play a crucial role in the innate immune system of the host and can be found in nature. Some of these molecules have shown broad-spectrum antimicrobial properties and wound-healing activity, making them good potential therapeutic compounds to treat DFUs. 
  • 592
  • 03 Mar 2023
Topic Review
Use of Grape Berries in Culinary Dishes
A good pairing is based on the complementary role of wine on the four critical factors of food: components, textures, flavors, and colors. Everyday wine and food examples of food preparation with wine or vine products, such as grapes or vine leaves, exemplify numerous similarities and contrasting characteristics in those four parameters, which we can find in an enjoyable meal. The knowledge of the internal anatomy and composition of both grape berries, which includes the skin, the mesocarp, and the endocarp, and vine leaf, which consists of the vascular system, parenchymatous mesophyll, and epidermis, is essential to know how to develop new, tastier and healthier dishes.
  • 391
  • 13 Sep 2023
Topic Review
Use of Glucagon-Like Peptide-1
Glucagon-like peptide-1 (GLP-1) is a human incretin hormone derived from the proglucagon molecule. GLP-1 receptor agonists are frequently used to treat type 2 diabetes mellitus and obesity. However, the hormone affects the liver, pancreas, brain, fat cells, heart, and gastrointestinal tract. The results showed that GLP-1 agonists can benefit defined off-medication motor scores in Parkinson’s Disease and improve emotional well-being. In Alzheimer’s disease, GLP-1 analogs can improve the brain’s glucose metabolism by improving glucose transport across the blood–brain barrier. In depression, the analogs can improve quality of life and depression scales. GLP-1 analogs can also have a role in treating chemical dependency, inhibiting dopaminergic release in the brain’s reward centers, decreasing withdrawal effects and relapses. These medications can also improve lipotoxicity by reducing visceral adiposity and decreasing liver fat deposition, reducing insulin resistance and the development of non-alcoholic fatty liver diseases. The adverse effects are primarily gastrointestinal. Therefore, GLP-1 analogs can benefit other conditions besides traditional diabetes and obesity uses.
  • 1.0K
  • 10 Jul 2022
Topic Review
Use of Genomic Databases in Medicine
Attention has been increasingly focused on the non-coding sequences that encompass 98% of the genome and may play an important regulatory function. The first WGS-based datasets have already been released including underrepresented populations. Although many databases contain pooled data from several cohorts, the importance of local databases has been highlighted. Genomic databases are not only collecting data but may also contribute to better diagnostics and therapies. They may find applications in population studies, rare diseases, oncology, pharmacogenetics, and infectious and inflammatory diseases. Further data may be analysed with Al technologies and in the context of other omics data. 
  • 409
  • 21 Apr 2023
Topic Review
Use of Fourier-Transform Infrared Spectroscopy
The Fourier-transform infrared (FTIR) spectroscopy method is a method of bond characterization that could be used quantitatively and qualitatively with X-ray fluorescence (XRF), X-ray diffraction (XRD), scanning electron microscopy, and electron energy dispersive spectroscopy (SEM/EDS) to study the chemical composition, compound composition, microstructural morphology, and their elemental compositions in CB applications, respectively.
  • 808
  • 14 Mar 2023
Topic Review
Use of Force by States
The use of force by states is controlled by both customary international law and by treaty law. The UN Charter reads in article 2(4): This principle is now considered to be a part of customary international law, and has the effect of banning the use of armed force except for two situations authorized by the UN Charter. Firstly, the Security Council, under powers granted in articles 24 and 25, and Chapter VII of the Charter, may authorize collective action to maintain or enforce international peace and security. Secondly, Article 51 also states that: "Nothing in the present Charter shall impair the inherent right to individual or collective self-defence if an armed attack occurs against a state." There are also more controversial claims by some states of a right of humanitarian intervention, reprisals and the protection of nationals abroad.
  • 862
  • 08 Oct 2022
Topic Review
Use of Food Delivery Apps
The pandemic forced both organizations and consumers to make many adjustments to their daily lives. However, due the technological advances that have been seen in recent years, some tools have become much more widely used. Among them are the food delivery applications (FDAs) that experienced an exponential growth during the pandemic. During the COVID-19 pandemic, the use of food delivery applications (FDAs) has not only met the requirements of businesses but also the demands of customers for convenient food supplies and personal safety concerns since these applications allow customers to effectively and easily order and access their food from several restaurants at convenient times and locations
  • 1.0K
  • 19 Jul 2022
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