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Topic Review
Variobahn
The Variobahn, formerly known as the Variotram, is a German-designed model of articulated low-floor tram and light rail vehicle. Since its introduction in 1993, the Variobahn has been manufactured variously by ABB, Adtranz, Bombardier Transportation, and since 2001 by Stadler Rail. As of 2009, 254 trams have been ordered, with an additional 110 on option. A unit costs about €2.5 million. Operators include the Graz Holding, the Bergen Light Rail, the Chemnitz Tramway, Verkehrsverbund Rhein-Ruhr, the Helsinki Tramway, the Rhine Neckar Area Tramway and London Tramlink.
  • 898
  • 09 Nov 2022
Topic Review
Varied Microbiome Profiles in Neonates
The field of human microbiome and gut microbial diversity research has witnessed a profound transformation, driven by advances in omics technologies. These advancements have unveiled essential connections between microbiome alterations and severe conditions, prompting the development of new frameworks through epidemiological studies. Traditionally, it was believed that each individual harbored unique microbial communities acquired early in life, evolving over the course of their lifetime, with little acknowledgment of any prenatal microbial development, but research challenges this belief. The neonatal microbiome’s onset, influenced by factors like delivery mode and maternal health, remains a subject of intense debate, hinting at potential intrauterine microbial processes. 
  • 159
  • 05 Jan 2024
Topic Review
Varidnaviria
Varidnaviria is a realm of viruses that includes all DNA viruses that encode major capsid proteins that contain a vertical jelly roll fold. The major capsid proteins (MCP) form into pseudohexameric subunits of the viral capsid, which stores the viral deoxyribonucleic acid (DNA), and are perpendicular, or vertical, to the surface of the capsid. Apart from this, viruses in the realm also share many other characteristics, such as minor capsid proteins (mCP) with the vertical jelly roll fold, an ATPase that packages viral DNA into the capsid, and a DNA polymerase that replicates the viral genome. Varidnaviria was established in 2019 based on the shared characteristics of the viruses in the realm. There are two groups of viruses in Varidnaviria: viruses that have a double vertical jelly roll (DJR) folds in the MCP, assigned to the kingdom Bamfordvirae, and viruses that have a single vertical jelly roll (SJR) fold in the MCP, assigned to the kingdom Helvetiavirae. The DJR-MCP lineage is thought to be descended from the SJR-MCP lineage via a gene fusion event, and the SJR-MCP shows a close relation to nucleoplasmins, pointing to a possible origin of the realm's jelly roll fold MCP. Most identified eukaryotic DNA viruses belong to Varidnaviria. Marine viruses in the realm are highly abundant worldwide and are important in marine ecology. Many animal viruses in the realm are associated with disease, including adenoviruses, poxviruses, and the African swine fever virus. Poxviruses have been prominent in the history of medicine, especially smallpox, caused by Variola virus, which was the target of the first vaccine and which later became the first disease eradicated. The realm also notably includes giant viruses that are physically larger and contain a much larger number of genes than typical viruses.
  • 730
  • 20 Oct 2022
Topic Review
Varicose Veins of the Lower Limbs
One of the early symptoms of chronic venous disease (CVD) is varicose veins (VV) of the lower limbs. There are many etiological environmental factors influencing the development of chronic venous insufficiency (CVI), although genetic factors and family history of the disease play a key role.
  • 218
  • 07 Feb 2024
Topic Review
Varicocele
Varicocele treatment is beneficial in improving semen parameters and pregnancy rate when an appropriate selection of patients is made. The purpose of treating varicocele in adults is mainly to improve current fertility status. On the other hand, the goal of treatment in adolescents is to prevent testicular injury and maintain testicular function for future fertility. Hence, the key to the success of varicocele treatment seems to be a correct indication. 
  • 313
  • 28 Jun 2023
Topic Review
Varicella-Zoster Virus Prevalence among Pregnant Women
Varicella-zoster virus (VZV) is a human-specific α-herpes virus responsible for chickenpox and herpes zoster. VZV is a virus with a lipid-rich envelope acquired from cellular membranes, where viral glycoproteins are inserted. Inside the envelope, a tegument layer formed by regulatory proteins surrounds an icosahedral nucleocapsid core containing the linear double-stranded DNA genome.
  • 361
  • 10 Mar 2023
Topic Review
Variants of SARS-CoV-2
The immune response elicited by the current COVID-19 vaccinations declines with time, especially among the immunocompromised population. Furthermore, the emergence of novel SARS-CoV-2 variants, particularly the Omicron variant, has raised serious concerns about the efficacy of currently available vaccines in protecting the most vulnerable people.
  • 556
  • 19 Apr 2023
Topic Review
Variants of Point Cloud Registration Algorithms
The registration of point clouds is relevant in many application domains, e.g., remote sensing, computer vision, robotics, autonomous driving, or healthcare. The general objective is to minimize the distances between overlapping point clouds.
  • 250
  • 24 Nov 2023
Topic Review
Variants and Immunity for Non-Hospitalized COVID-19 Patients
The continuing transmission of coronavirus disease 2019 (COVID-19) remains a world-wide 21st-century public health emergency of concern. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused greater than 600 million cases of COVID-19 and over 6 million deaths globally. COVID-19 continues to be a highly transmissible disease despite efforts by public health officials and healthcare providers to manage and control the disease. Variants identified in selected worldwide epicenters add to the complexity of vaccine efficacy, overage, and antibody titer maintenance and bioactivity. The identification of the SARS-CoV-2 variants is described with respect to evading protective efficacy of COVID-19 vaccines and breakthrough infections. Vaccines and other therapeutics have prevented millions of SARS-CoV-2 infections and thousands of deaths in the United States.
  • 288
  • 27 Jul 2023
Topic Review
Variant Chinese Character
Variant Chinese characters (simplified Chinese: 异体字; traditional Chinese: 異體字; pinyin: yìtǐzì; Kanji: 異体字; Hepburn: itaiji; Korean: 이체자; Hanja: 異體字; Revised Romanization: icheja) are Chinese characters that are homophones and synonyms. Most variants are allographs in most circumstances, such as casual handwriting. Some contexts require the usage of certain variants, such as in textbook editing.
  • 966
  • 29 Nov 2022
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