Topic Review
Topical Antifungal-Corticosteroid Combinations
A broad range of topical antifungal formulations containing miconazole or terbinafine as actives are commonly used as efficacious choices for combating fungal skin infections. Their many benefits, owing to their specific mechanism of action, include their ability to target the site of infection, enhance treatment efficacy and reduce the risk of systemic side effects. Their proven efficacy, and positioning in the treatment of fungal skin infections, is enhanced by high patient compliance, especially when appropriate vehicles such as creams, ointments and gels are used.
  • 5.5K
  • 18 Aug 2022
Topic Review
Iranian Plateau
The Iranian Plateau or the Persian Plateau is a geological feature in Central Asia, South Asia, and Western Asia. It is the part of the Eurasian Plate wedged between the Arabian and Indian plates, situated between the Zagros Mountains to the west, the Caspian Sea and the Kopet Dag to the north, the Armenian Highlands and the Caucasus Mountains in the northwest, the Strait of Hormuz and the Persian Gulf to the south and the Indo-Gangetic Plain to the east in Indian subcontinent. As a historical region, it includes Parthia, Media, Persis, the heartlands of Iran and some of the previous territories of Greater Iran. The Zagros Mountains form the plateau's western boundary, and its eastern slopes may be included in the term. The Encyclopædia Britannica excludes "lowland Khuzestan" explicitly and characterizes Elam as spanning "the region from the Mesopotamian Plain to the Iranian Plateau". From the Caspian in the northwest to Balochistan in the south-east, the Iranian Plateau extends for close to 2,000 km. It encompasses the greater part of Iran, all of Afghanistan, and Pakistan west of the Indus River containing some 3,700,000 square kilometres (1,400,000 sq mi). In spite of being called a "plateau", it is far from flat but contains several mountain ranges, the highest peak being Damavand in the Alborz at 5610 m, and the Dasht-e Lut east of Kerman in Central Iran falling below 300 m.
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  • 22 Nov 2022
Topic Review
Straight-Three Engine
A straight-three engine, also known as an inline-triple, or inline-three (abbreviated I3 or L3), is a reciprocating piston internal combustion engine with three cylinders arranged in a straight line or plane, side by side.
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  • 31 Oct 2022
Topic Review
Carbon Emission Efficiency
Carbon emission efficiency is an important concept in environmental science; it refers to the economic benefits generated by production activities that produce carbon emissions at the same time. The less carbon emissions generated per unit of economic output, the more carbon emission efficient it is.
  • 5.4K
  • 26 May 2022
Topic Review
Electrical Double-Layer Capacitors
Capacitors with superior characteristics (called supercapacitors), which are unavailable in conventional batteries, exhibit excellent functionality in many areas, including power density, charge/discharge cycles, operation over a wide temperature range, and reliability, which have been noted as limits of batteries.
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  • 08 Jan 2021
Topic Review
Correlation and Dependence
In statistics, correlation or dependence is any statistical relationship, whether causal or not, between two random variables or bivariate data. In the broadest sense correlation is any statistical association, though it commonly refers to the degree to which a pair of variables are linearly related. Familiar examples of dependent phenomena include the correlation between the height of parents and their offspring, and the correlation between the price of a good and the quantity the consumers are willing to purchase, as it is depicted in the so-called demand curve. Correlations are useful because they can indicate a predictive relationship that can be exploited in practice. For example, an electrical utility may produce less power on a mild day based on the correlation between electricity demand and weather. In this example, there is a causal relationship, because extreme weather causes people to use more electricity for heating or cooling. However, in general, the presence of a correlation is not sufficient to infer the presence of a causal relationship (i.e., correlation does not imply causation). Formally, random variables are dependent if they do not satisfy a mathematical property of probabilistic independence. In informal parlance, correlation is synonymous with dependence. However, when used in a technical sense, correlation refers to any of several specific types of mathematical operations between the tested variables and their respective expected values. Essentially, correlation is the measure of how two or more variables are related to one another. There are several correlation coefficients, often denoted [math]\displaystyle{ \rho }[/math] or [math]\displaystyle{ r }[/math], measuring the degree of correlation. The most common of these is the Pearson correlation coefficient, which is sensitive only to a linear relationship between two variables (which may be present even when one variable is a nonlinear function of the other). Other correlation coefficients – such as Spearman's rank correlation – have been developed to be more robust than Pearson's, that is, more sensitive to nonlinear relationships. Mutual information can also be applied to measure dependence between two variables.
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  • 14 Oct 2022
Topic Review
List of Phobias
The English suffixes -phobia, -phobic, -phobe (from Greek φόβος phobos, "fear") occur in technical usage in psychiatry to construct words that describe irrational, abnormal, unwarranted, persistent, or disabling fear as a mental disorder (e.g. agoraphobia), in chemistry to describe chemical aversions (e.g. hydrophobic), in biology to describe organisms that dislike certain conditions (e.g. acidophobia), and in medicine to describe hypersensitivity to a stimulus, usually sensory (e.g. photophobia). In common usage, they also form words that describe dislike or hatred of a particular thing or subject (e.g. homophobia). The suffix is antonymic to -phil-. For more information on the psychiatric side, including how psychiatry groups phobias such as agoraphobia, social phobia, or simple phobia, see phobia. The following lists include words ending in -phobia, and include fears that have acquired names. In some cases, the naming of phobias has become a word game, of notable example being a 1998 humorous article published by BBC News. In some cases, a word ending in -phobia may have an antonym with the suffix -phil-, e.g. Germanophobe/Germanophile. Many -phobia lists circulate on the Internet, with words collected from indiscriminate sources, often copying each other. Also, a number of psychiatric websites exist that at the first glance cover a huge number of phobias, but in fact use a standard text to fit any phobia and reuse it for all unusual phobias by merely changing the name. Sometimes it leads to bizarre results, such as suggestions to cure "prostitute phobia". Such practice is known as content spamming and is used to attract search engines. An article published in 1897 in American Journal of Psychology noted "the absurd tendency to give Greek names to objects feared (which, as Arndt says, would give us such terms as klopsophobia – fear of thieves, triakaidekaphobia – fear of the number 13....)".
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  • 07 Nov 2022
Topic Review
Cybersecurity Economics
Cybersecurity economics can be defined as a field of research that utilizes a socio-technical perspective to investigate economic aspects of cybersecurity such as budgeting, information asymmetry, governance, and types of goods and services, to provide sustainable policy recommendations, regulatory options, and practical solutions that can substantially improve the cybersecurity posture of the interacting agents in the open socio-technical systems.   
  • 5.4K
  • 15 Dec 2021
Topic Review
Edge Couplers
Silicon photonics has drawn increasing attention since recent decades and is promising to act as a key technology for future daily applications due to its various merits including ultra-low cost, high integration density owing to the high refractive index of silicon and compatibility with current semiconductor fabrication process. Optical interconnects is an important issue in silicon photonic integrated circuits to transmit light and fiber-to-chip optical interconnects is vital in application scenarios like data centers and optical transmission systems. There are mainly two categories of fiber-to-chip optical coupling, that is off-plane coupling and in-plane coupling. Grating couplers work under the former category while edge couplers function as in-plane coupling. In this paper, we mainly focus on edge couplers in silicon photonic integrated circuits. We deliver an introduction to the research background, operation mechanism and design principles of silicon photonic edge couplers. The state-of-the-art of edge couplers is reviewed according to different configurations as to the device structure, identifying the performance, fabrication feasibility and applications. In addition, a brief comparison between edge couplers and grating couplers is conducted. Packaging issue is also discussed and several prospective techniques for further improvements of edge couplers are proposed.
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  • 27 Oct 2020
Topic Review
Frogs in Culture
Frogs play a variety of roles in culture, appearing in folklore and fairy tales such as the Brothers Grimm story of The Frog Prince. In ancient Egypt and Mesopotamia, frogs symbolized fertility, while in classical antiquity, the Greeks and Romans associated frogs with fertility, harmony, and licentiousness. Frogs are the subjects of fables attributed to Aesop, of proverbs in various cultures, and of art. Frog characters such as Kermit the frog and Pepe the Frog feature in popular culture. They are eaten in some parts of the world including France. In Australia, a fondant dessert is known as frog cake.
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  • 27 Nov 2022
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