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Topic Review
Columba
Columba, Latin for "dove," is a constellation in the southern celestial hemisphere. First introduced by Dutch astronomer Petrus Plancius in the late 16th century, it represents the dove released by Noah from the ark in the biblical story of the Great Flood. Despite its small size, Columba contains several notable celestial objects, including the famous globular cluster NGC 1851 and various open star clusters, making it an intriguing target for astronomers and stargazers alike.
  • 191
  • 08 Mar 2024
Topic Review
Red Fox
The Red Fox (Vulpes vulpes) is a highly adaptable mammal belonging to the Canidae family, widely distributed across the Northern Hemisphere. Renowned for its stunning reddish-orange fur and bushy tail, the Red Fox is a proficient predator, preying on small mammals, birds, and even insects. Its remarkable ability to thrive in various habitats, from forests to urban areas, has cemented its status as one of the most successful carnivores worldwide.
  • 309
  • 08 Mar 2024
Topic Review
Circinus
Circinus is a small, faint constellation located in the southern sky. Named after the Latin word for compass, it was first introduced in the 18th century by the French astronomer Nicolas Louis de Lacaille during his observations of the southern hemisphere. Despite its modest size, Circinus harbors several intriguing celestial objects, including a notable planetary nebula and multiple star systems of scientific interest.
  • 205
  • 08 Mar 2024
Topic Review
Chamaeleon
Chamaeleon, a small and inconspicuous constellation in the southern celestial hemisphere, represents the chameleon, a creature known for its ability to change color and blend into its surroundings. Despite its modest size, Chamaeleon holds significance in astronomy for its proximity to the southern celestial pole and its role in studying star formation and stellar evolution.
  • 185
  • 08 Mar 2024
Topic Review
Cetus
Cetus, known as the Whale, is a large constellation visible in the southern sky. In Greek mythology, Cetus represents the sea monster sent by Poseidon to terrorize the kingdom of Aethiopia, eventually slain by Perseus to rescue Andromeda. As one of the 88 recognized constellations, Cetus holds a special place in the realm of astronomy and mythology. 
  • 250
  • 08 Mar 2024
Topic Review
Categories of Cloud-Based Interactive Applications
A cloud-based interactive application (CIA) is an application running in the cloud with stringent interactivity requirements, such as remote desktop and cloud gaming. These services have experienced a surge in usage, primarily due to the adoption of new remote work practices during the pandemic and the emergence of entertainment schemes similar to cloud gaming platforms. Evaluating the quality of experience (QoE) in these applications requires specific metrics, including interactivity time, responsiveness, and the assessment of video- and audio-quality degradation. 
  • 167
  • 08 Mar 2024
Topic Review
ATR Pathway as a Therapeutic Target for Cancer
The DNA damage response (DDR) system is a complicated network of signaling pathways that detects and repairs DNA damage or induces apoptosis. Critical regulators of the DDR network include the DNA damage kinases ataxia telangiectasia mutated Rad3-related kinase (ATR) and ataxia-telangiectasia mutated (ATM). The ATR pathway coordinates processes such as replication stress response, stabilization of replication forks, cell cycle arrest, and DNA repair. ATR inhibition disrupts these functions, causing a reduction of DNA repair, accumulation of DNA damage, replication fork collapse, inappropriate mitotic entry, and mitotic catastrophe. Data have shown that the inhibition of ATR can lead to synthetic lethality in ATM-deficient malignancies. In addition, ATR inhibition plays a significant role in the activation of the immune system by increasing the tumor mutational burden and neoantigen load as well as by triggering the accumulation of cytosolic DNA and subsequently inducing the cGAS-STING pathway and the type I IFN response. 
  • 132
  • 08 Mar 2024
Topic Review
Current Trends in the Development of Fungal-Containing Consortia
There is growing interest in the creation of artificial microbial consortia, especially in the field of developing and applying various bioremediation processes. Heavy metals, dyes, synthetic polymers (microplastics), pesticides, polycyclic aromatic hydrocarbons and pharmaceutical agents are among the pollutants that have been mainly targeted by bioremediation based on various consortia containing fungi and yeasts. Such consortia can be designed both for the treatment of soil and water. 
  • 130
  • 08 Mar 2024
Topic Review
Machine Vision and Industry 4.0 to Industry 5.0
With the emergence of artificial intelligence (AI) and its integration into various intelligent robotics, the Fourth Industrial Revolution, also known as Industry 4.0, managed to trigger changes. Its need has been emphasized in multiple situations, such as that of the COVID-19 pandemic, entering every area of human life, with Industry 4.0 being more and more involved in production processes. Industry 4.0 is an emerging concept that is multidisciplinary and complex. Leveraging not just one, but a patchwork of technologies that can work individually as well as in combination, Industry 4.0 strives to achieve a more general digital transformation with high expectations both in the production of products and services in real-time. This effort is mainly based on advanced computers with fast processors able to store, manage, process, and analyze a large amount of data, spending less time and resources than ever before.
  • 174
  • 08 Mar 2024
Topic Review
Advanced Persistent Thread and Common Systems Behavioral Sources
The rapid proliferation of Internet of Things (IoT) networks in Colombia and various global regions has unquestionably resulted in a significant increase in cyberattacks. This rapid expansion of interconnected devices carries significant implications for individuals, organizations, and governing entities.
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  • 08 Mar 2024
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