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Topic Review
Object-Relational Database
An object-relational database (ORD), or object-relational database management system (ORDBMS), is a database management system (DBMS) similar to a relational database, but with an object-oriented database model: objects, classes and inheritance are directly supported in database schemas and in the query language. In addition, just as with pure relational systems, it supports extension of the data model with custom data types and methods. An object-relational database can be said to provide a middle ground between relational databases and object-oriented databases. In object-relational databases, the approach is essentially that of relational databases: the data resides in the database and is manipulated collectively with queries in a query language; at the other extreme are OODBMSes in which the database is essentially a persistent object store for software written in an object-oriented programming language, with a programming API for storing and retrieving objects, and little or no specific support for querying.
  • 3.5K
  • 04 Nov 2022
Topic Review
Physiologically Based Pharmacokinetic Modeling of Nanoparticle Biodistribution
Cancer treatment and pharmaceutical development require targeted treatment and less toxic therapeutic intervention to achieve real progress against this disease. In this scenario, nanomedicine emerged as a reliable tool to improve drug pharmacokinetics and to translate to the clinical biologics based on large molecules. However, the ability of body to recognize foreign objects together with carrier transport heterogeneity derived from the combination of particle physical and chemical properties, payload and surface modification, make the designing of effective carriers very difficult. In this scenario, physiologically based pharmacokinetic modeling can help to design the particles and eventually predict their ability to reach the target and treat the tumor. This effort is performed by scientists with specific expertise and skills and familiarity with artificial intelligence tools such as advanced software that are not usually in the “cords” of traditional medical or material researchers. 
  • 673
  • 04 Nov 2022
Topic Review
Xbox One System Software
The Xbox One system software, sometimes called the Xbox OS, or Xbox Dashboard (when a person is referring to software updates), is the operating system developed exclusively for the Xbox One consoles. It is a Microsoft Windows-based operating system using the Hyper-V virtual machine monitor and contains separate operating systems for games and applications that can run on the console. It is located on the internal HDD for day-to-day usage, while also being duplicated on the internal NAND storage of the console for recovery purposes and factory reset functionality. The Xbox One allows users to download applications that add to the functionality of the dashboard. From June 2014 onwards, entertainment apps no longer required the user to be signed into a valid Xbox Live Gold account in order to use the features advertised for the given app. Since launch, Microsoft has been updating the OS monthly, with updates downloaded from the Xbox Live service directly to the Xbox One and subsequently installed, or by using offline recovery images downloaded via a PC. In November 2015, a major system update known as the New Xbox One Experience was released, which brought very significant changes to the design and functionality of the system. The Windows 10-based Core had replaced the Windows 8-based one in this update, and the new system is sometimes referred to as "Windows 10 on Xbox One".
  • 5.7K
  • 03 Nov 2022
Topic Review
QVD
QVD is an open-source virtual desktop infrastructure (VDI) product built on Linux. Its main purpose is to provide remote desktops to users.
  • 390
  • 03 Nov 2022
Topic Review
News Feed
News Feed is a feature of the social network Facebook. The web feed is the primary system through which users are exposed to content posted on the network. News Feed highlights information that includes profile changes, upcoming events, and birthdays, among other updates. Using a proprietary method, Facebook selects a handful of updates to show users every time they visit their feed, out of an average of 2,000 updates they can potentially receive. Over two billion people use Facebook every month, making the network's News Feed the most viewed and most influential aspect of the news industry.
  • 789
  • 03 Nov 2022
Topic Review
Math 55
Math 55 is a two-semester long first-year undergraduate mathematics course at Harvard University, founded by Lynn Loomis and Shlomo Sternberg. The official titles of the course are Honors Abstract Algebra (Math 55a) and Honors Real and Complex Analysis (Math 55b). Previously, the official title was Honors Advanced Calculus and Linear Algebra.
  • 4.4K
  • 03 Nov 2022
Topic Review
Kübler-Ross Model
The Kübler-Ross model, or the Five Stages of Grief, postulates a series of emotions experienced by terminally ill patients prior to death, or people who have lost a loved one, wherein the five stages are: denial, anger, bargaining, depression, and acceptance. Although commonly referenced in popular media, the existence of these stages has not been empirically demonstrated and the model is not considered helpful in explaining the grieving process. It is considered to be of historical value but outdated in scientific terms and in clinical practice. The model was first introduced by Swiss-American psychiatrist Elisabeth Kübler-Ross in her 1969 book On Death and Dying, and was inspired by her work with terminally ill patients. Motivated by the lack of instruction in medical schools on the subject of death and dying, Kübler-Ross examined death and those faced with it at the University of Chicago's medical school. Kübler-Ross's project evolved into a series of seminars which, along with patient interviews and previous research, became the foundation for her book. Although Kübler-Ross is commonly credited with creating stage models, earlier bereavement theorists and clinicians such as Erich Lindemann, Collin Murray Parkes, and John Bowlby used similar models of stages of phases as early as the 1940s. Later in her life, Kübler-Ross noted that the stages are not a linear and predictable progression and that she regretted writing them in a way that was misunderstood. "Kübler-Ross originally saw these stages as reflecting how people cope with illness and dying," observed grief researcher Kenneth J. Doka, "not as reflections of how people grieve."
  • 2.4K
  • 03 Nov 2022
Topic Review
Alundra 2: A New Legend Begins
Alundra 2: A New Legend Begins (アランドラ2 魔進化の謎, Arandora 2 Ma Shinka no Nazo, Alundra 2: The Mystery of Magic Evolution) is an action role-playing game developed by Matrix Software for the Sony PlayStation. It was published by SCEI in Japan and Activision worldwide. Unlike its predecessor, Alundra, Alundra 2 features a 3D look which opens up a new world of puzzles. Also, despite its title, Alundra 2 is a standalone sequel, and has no ties with the original. It has a whole new story with a different set of characters, including the main character, Flint. Compared to the darker storyline of Alundra, Alundra 2 has a more light-hearted storyline.
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  • 03 Nov 2022
Topic Review
Panjab Digital Library
The Panjab Digital Library is a voluntary organization digitizing and preserving the cultural heritage of Panjab since 2003. With over 45 million digitized pages, it is the biggest resource of digital material on Panjab. There are many historically significant documents stored and made available online. Its scope covers Sikh and Punjabi culture. The library funded by The Nanakshahi Trust was launched online in August 2009. Its base office is located at Chandigarh, India. The library's mission is to locate, digitize, preserve, collect and make accessible the accumulated wisdom of the Panjab region, without distinction as to script, language, religion, nationality, or other physical condition.
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  • 03 Nov 2022
Topic Review
Single-Letter Second-Level Domain
Single-letter second-level domains are domain names in which the second-level domain consists of only one letter, such as x.com. In 1993, the Internet Assigned Numbers Authority (IANA) explicitly reserved all single-letter and single-digit second-level domain names in the top-level domains com, net, and org, and grandfathered those that had already been assigned. In December 2005, ICANN considered auctioning these domains.
  • 2.7K
  • 03 Nov 2022
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