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Topic Review
Bioengineered Skin Substitutes
This review presents the common commercially available skin substitutes and their clinical use. Moreover, the choice of an appropriate hydrogel type to prepare cell-laden skin substitutes is discussed. Additionally, we present recent advances in the field of bioengineered human skin substitutes using three-dimensional (3D) bioprinting techniques. Finally, we discuss different skin substitute developments to meet different criteria for optimal wound healing.
  • 649
  • 14 Mar 2021
Topic Review
Skin Collagen Fiber Turnover and Functioning
Clinically, collagen formation disorders manifest themselves as increased flabbiness and looseness of the skin and as early signs of facial aging. In addition to the clinical picture, it is important for cosmetologists and dermatologists to understand the etiology and pathogenesis of collagenopathies. This entry summarized and systematized the available information concerning the role of genetic and epigenetic factors in skin collagen fiber turnover.
  • 649
  • 21 Oct 2021
Biography
Montserrat
My name is Montserrat Fernández-Guarino, I am dermatologist in Madrid, Spain. I have studied medicine and I am specialist, however I have so many more interest. Among the intellectual fields, I am graduated in Psychology, and coursed different master´s degree, in nutrition, medical nutrition in diseases, sports injury rehabilitation and pharmacy office. Summary of the present position: -Staf
  • 647
  • 22 May 2023
Topic Review
New Topical Agents for Onychomycosis
Onychomycosis is a common nail disease caused by fungi. The primary pathogens are dermatophytes, yeasts, non-dermatophyte moulds, and mixed fungal populations may also contribute to the development of a recalcitrant condition, usually accompanied by difficulties in everyday life and severe emotional stress. Treatment failure and relapse of the infection are the most frequent problems. Resistance to antifungals, an increasing number of comorbidities, and polydrug use among the ageing population are imperatives that impose a shift to safer drugs. Topical antifungals are considered less toxic and minimally interact with other drugs.
  • 641
  • 19 Oct 2022
Topic Review
Dermatitis Herpetiformis
Dermatitis herpetiformis (DH) is a blistering dermatosis, which shares common immunologic features with celiac disease (CD).
  • 641
  • 12 Oct 2021
Topic Review
Anti-Melanogenic Activity of Calocedrus formosana Wood Essential Oil
Calocedrus formosana (Cupressaceae) is one of the five precious woods of Taiwan. C. formosana wood essential oil (CFEO) could be a potential melanogenesis inhibitor.  Among the composition of C. formosana wood essential oil (CFEO), thymol exhibited the strongest the inhibitory melanin production activity the anti-melanogenesis principal of CFEO might be thymol. 
  • 639
  • 03 Mar 2022
Topic Review
Novel Signaling Pathways in PV
The immunobullous condition Pemphigus Vulgaris (PV) is caused by autoantibodies targeting the desmosomal adhesion proteins, leading to blistering in the skin and mucosal membrane. There is still no cure to the disease apart from the use of corticosteroids and immunosuppressive agents. 
  • 638
  • 22 Sep 2021
Topic Review
Erbium Laser for Skin Surgery
The Erbium laser is a very versatile laser system used in dermatology. Its ability to be almost selectively absorbed by water makes it a perfect device for managing various cutaneous skin conditions.
  • 638
  • 01 Dec 2021
Topic Review
Atopic Dermatitis—Beyond the Skin
Atopic dermatitis is a chronic inflammatory disease that can arise during the first months of life or at maturity and have a significant negative impact on the quality of life. The main pathogenic mechanism is the breakdown of cutaneous barrier integrity, which is associated with systemic inflammatory immunologic disorders. Atopic dermatitis involves numerous immunologic, allergic, respiratory, and ophthalmologic comorbidities that develop through similar intricate pathogenic phenomena.
  • 638
  • 30 Sep 2021
Topic Review
Obesity and Wound Healing
Chronic wounds represent nowadays a major challenge for both clinicians and researchers in the regenerative setting. Obesity represents one of the major comorbidities in patients affected by chronic ulcers and therefore diverse studies aimed at assessing possible links between these two morbid conditions are currently ongoing. In particular, adipose tissue has recently been described as having metabolic and endocrine functions rather than serving as a mere fat storage deposit. In this setting, adipose-derived stem cells, a peculiar subset of mesenchymal stromal/stem cells (MSCs) located in adipose tissue, have been demonstrated to possess regenerative and immunological functions with a key role in regulating both adipocyte function and skin regeneration.
  • 635
  • 24 Mar 2023
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