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Topic Review
Augmented and Virtual Reality in Dermatology
Augmented reality (AR) is a component of virtual reality (VR) or virtual environments (VE) where the user is completely immersed into a synthetic environment. While in VR, the user does not see the real world. Instead, AR allows us to superimpose virtual objects onto real ones. The number of AR/VR applications has undeniably exploded over the last decades. While both techniques have been extensively used in various medical fields, such as in plastic surgery, little investigation has been performed so far in dermatology.
  • 706
  • 09 Mar 2022
Topic Review
Therapeutic Managements for Autoimmune Bullous Skin Disorders
Autoimmune bullous skin disorders are a group of disorders characterized by the formation of numerous blisters and erosions on the skin and/or the mucosal membrane, arising from autoantibodies against the intercellular adhesion molecules and the structural proteins. They can be classified into intraepithelial or subepithelial autoimmune bullous dermatoses based on the location of the targeted antigens. These dermatoses are extremely debilitating and fatal in certain cases, depending on the degree of cutaneous and mucosal involvement. Effective treatments should be implemented promptly. Glucocorticoids serve as the first-line approach due to their rapid onset of therapeutic effects and remission of the acute phase. Nonetheless, long-term applications may lead to major adverse effects that outweigh the benefits. Hence, other adjuvant therapies are mandatory to minimize the potential harm and ameliorate the quality of life.
  • 704
  • 30 Jun 2022
Topic Review
Factors Contributing to Atopic Dermatitis Development
Atopic dermatitis (AD) or atopic eczema is an increasingly manifested inflammatory skin disorder of complex etiology which is modulated by both extrinsic and intrinsic factors. Immune dysregulation, barrier dysfunction, hormonal fluctuations, and skin microbiome dysbiosis are important factors contributing to AD development, and their in-depth understanding is crucial not only for AD treatment but also for similar inflammatory disorders.
  • 697
  • 29 Jun 2023
Topic Review
Aromatherapy for Symptom Relief in Patients with Burn
Aromatherapy, also known as essential oil therapy, uses plant, flower, or herb extracts to enhance health and wellbeing. Aromatic essential oils have been widely studied for first-degree burn injuries due to their ability to relieve pain, reduce scarring, as well as reduce inflammation and antimicrobial activity. 
  • 697
  • 24 Feb 2022
Topic Review
Tranexamic Acid in Melasma and Sun-Induced Hyperpigmentation Treatment
Tranexamic acid (TXA) has anti-plasmin activity and has been shown when administered orally to be effective against melasma, for which it is considered first-line pharmacotherapy. Several studies have shown that topically applied TXA is also effective against melasma and skin hyperpigmentation caused by sunburn and inflammation. The TXA concentration in the epidermis and dermis/vasculature has been estimated from its distribution in the skin after closed application, and topically applied TXA has thus been shown to act on neutrophils and mast cells in the dermis and on the vascular system.
  • 696
  • 04 Nov 2022
Topic Review
Plaque Psoriasis and COVID-19
There is no evidence to support the idea that patients receiving systemic therapy (i.e. immunosuppressive/ immunomodulating agents) should stop their treatment in order to prevent COVID-19 infection. People with psoriasis undergoing systemic therapy should be advised to follow current guidelines for hygiene and physical distancing as recommended in their respective area of residence. Chronic plaque psoriasis is an inflammatory skin disease affecting 2–3% of the general population. In case of moderate to severe psoriasis patients are candidate to systemic treatments that have immunosuppressive/immunomodulating properties. 
  • 696
  • 31 Dec 2020
Topic Review
Artificial Intelligence in Dermatopathology
Artificial intelligence applied to pathological anatomyhas attracted a particular interest from pathologists and, in more detail, also from dermatopathologists. Increasing attention is being paid to the applications of AI and ML in the diagnosis of simple or more complex skin lesions, and the training of AI algorithms is gathering increasing feedback from the scientific community.
  • 691
  • 06 Sep 2021
Topic Review
Blue Light on Acne Vulgaris
Acne is a dermatosis that affects almost 90% of the adolescent population worldwide and its treatment is performed with retinoids, antimicrobials, acids, and topical or systemic antibiotics. Side effects such as skin irritation in addition to microbial resistance to antibiotics are the main side effects found. Phototherapy with blue light is being used as an alternative treatment.
  • 689
  • 11 Nov 2021
Topic Review
Nodular Trichoblastoma
Trichoblastoma (TB) is a rare biphasic benign adnexal neoplasm originating from follicular germ cells but clinically, it can simulate basal cell carcinoma (BCC), making the diagnosis more difficult.
  • 688
  • 20 Jul 2021
Topic Review
Pharmacological Wound Healing Evidence of Iberian Lamiaceae
The traditional use of the family Lamiaceae has been highlighted in several ethnobotanical assays carried out within the Iberian Peninsula. Usually, Lamiaceae species are rich essential oil-bearing plants with a great diversity of phenolic compounds, polyphenols, iridoids, diterpenoids, triterpenoids, saponins and, in some restricted cases, pyridine and pyrrolidine alkaloids.
  • 688
  • 01 Mar 2023
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