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Topic Review
Taekwondo Training and Obesity
Taekwondo training is an effective exercise that can prevent or positively improve obesity. In addition, Taekwondo has value as a lifestyle sport that can contribute to the promotion of human health, not just bounded in the field of martial arts and sports.
  • 1.3K
  • 24 Nov 2021
Topic Review
Dietary Macronutrients That Prompt MetS via Mitochondria
Metabolic syndrome (MetS) is a cluster of metabolic risk factors for diabetes, coronary heart disease, non-alcoholic fatty liver disease, and some tumors. It includes insulin resistance, visceral adiposity, hypertension, and dyslipidemia. MetS is primarily linked to lipotoxicity, with ectopic fat deposition from fat storage exhaustion, more than obesity per se. Excessive intake of long-chain saturated fatty acid and sugar closely relates to lipotoxicity and MetS through several pathways, including toll-like receptor 4 activation, peroxisome proliferator-activated receptor-gamma regulation (PPARγ), sphingolipids remodeling, and protein kinase C activation. These mechanisms prompt mitochondrial dysfunction, which plays a key role in disrupting the metabolism of fatty acids and proteins and in developing insulin resistance. 
  • 1.3K
  • 21 Mar 2023
Topic Review
Daylight Photodynamic Therapy
Daylight photodynamic therapy (dPDT) uses sunlight as a light source to treat superficial skin cancer. Using sunlight as a therapeutic device has been present for centuries, forming the basis of photodynamic therapy in the 20th century. Compared to conventional PDT, dPDT can be a less painful, more convenient and an effective alternative. The first clinical uses of dPDT on skin cancers began in Copenhagen in 2008. Currently, aminolevulinic acid-mediated dPDT has been approved to treat actinic keratosis patients in Europe.
  • 1.3K
  • 13 Dec 2020
Topic Review
Salvia hispanica and Salviae hispanicae semen
Salvia hispanica L. is a plant species that has been used since antiquity and is now highly valued for its unique nutritional and potential medicinal properties. Chia seeds have recently become one of the most popular food ingredients, with a number of beneficial effects on the functioning of the human body. The data presented under our review indicate that they are also a valuable health-promoting dietary supplement as well as cosmetic ingredient. Scientific studies on pharmacological activities of chia seeds proved their potential valuable role in the prevention of diseases which currently are considered a global health problem. The research confirmed the cardioprotective, antihypertensive, antidiabetic, antiatherosclerotic, nephroprotective, anti-inflammatory, as well as antioxidant properties.
  • 1.3K
  • 16 Feb 2022
Topic Review
Medical Applications of Chitin
Chitin is a universal biopolymer that is found in microbes, plants, fungi, the exoskeleton of insects, various species of algae, and bottom-feeding crustaceans. This (1–4)-linked N-acetyl-ß-D-glucosamine polysaccharide can be readily processed with simple chemical procedures without putting a species at risk. Chitin has garnered interest as an alternative substance that can be used in the medical, environmental, and agricultural sectors.
  • 1.3K
  • 29 Mar 2022
Topic Review Peer Reviewed
Dual-Modular Stems for Primary Total Hip Arthroplasty
In primary total hip arthroplasty (THA), dual-modular stems were introduced to better restore hip stability, femoral offset, and leg length. This entry highlights the gathered knowledge about dual-modular stems and related complications in combinations with titanium (Ti) and cobalt-chrome (CoCr) exchangeable necks. The reasons for a modular neck failure are multifactorial. Some of the dual-modular stems are still on the market despite the fact th these designs have neither been proven for durability nor have shown any clinical benefits for the patients as compared to monolithic stems. Apart from very limited indications, orthopaedic surgeons should not use dual-modular stem designs for primary THA. 
  • 1.3K
  • 27 Apr 2022
Topic Review
Treating Delusional Disorder with Antipsychotics
Delusional disorder (DD) has been considered a treatment-resistant disorder, with antipsychotics acknowledged as the best. It is possible that the discovery of the right drug could turn treatment resistance into treatment response.
  • 1.3K
  • 29 Dec 2022
Topic Review
Nickel-Titanium Rotary Instruments in Endodontics
Since the introduction of Nickel-Titanium alloy as the material of choice for the manufacturing of endodontic rotary instruments, the success rate of the root canal therapies has been significantly increased. This success mainly arises from the properties of the Nickel-Titanium alloy: the biocompatibility, the superelasticity and the shape memory effect. Those characteristics have led to a reduction in time of endodontic treatments, a simplification of instrumentation procedures and an increase of predictability and effectiveness of endodontic treatments. Nevertheless, the intracanal separation of Nickel-Titanium rotary instruments is still a major concern of endodontists, with a consequent possible reduction in the outcome rate. As thoroughly demonstrated, the two main causes of intracanal separation of endodontic instruments are the cyclic fatigue and the torsional loads. As results, in order to reduce the percentage of intracanal separation researches and manufacturers have been focused on the parameters that directly or indirectly influence mechanical properties of endodontic rotary instruments. This entry describes the current state of the art regarding the Nickel-Titanium alloy in endodontics, the mechanical behavior of endodontic rotary instruments and the relative stresses acting on them during intracanal instrumentation, highlighting the limitation of the current literature.
  • 1.3K
  • 24 Jan 2022
Topic Review
Additive Manufacturing Processes
Additive manufacturing (AM, 3D printing) is used in many fields and different industries. In the medical and dental field, every patient is unique and, therefore, AM has significant potential in personalized and customized solutions. This text explores what additive manufacturing processes and materials are utilized in medical and dental applications, especially focusing on processes that are less commonly used. The processes are categorized in ISO/ASTM process classes: powder bed fusion, material extrusion, VAT photopolymerization, material jetting, binder jetting, sheet lamination and directed energy deposition combined with classification of medical applications of AM. Based on the findings, it seems that directed energy deposition is utilized rarely only in implants and sheet lamination rarely for medical models or phantoms. Powder bed fusion, material extrusion and VAT photopolymerization are utilized in all categories. Material jetting is not used for implants and biomanufacturing, and binder jetting is not utilized for tools, instruments and parts for medical devices. The most common materials are thermoplastics, photopolymers and metals such as titanium alloys. If standard terminology of AM would be followed, this would allow a more systematic review of the utilization of different AM processes.
  • 1.3K
  • 09 Apr 2021
Topic Review
Deep Learning for Classification of Skin Cancer
One of the major health concerns for human society is skin cancer. When the pigments producing skin color turn carcinogenic, this disease gets contracted. A skin cancer diagnosis is a challenging process for dermatologists as many skin cancer pigments may appear similar in appearance. Hence, early detection of lesions (which form the base of skin cancer) is definitely critical and useful to completely cure the patients suffering from skin cancer. Significant progress has been made in developing automated tools for the diagnosis of skin cancer to assist dermatologists. The worldwide acceptance of artificial intelligence-supported tools has permitted usage of the enormous collection of images of lesions and benevolent sores approved by histopathology.
  • 1.3K
  • 13 Dec 2021
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