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Topic Review
Tourism-phobia
The perception of residents of tourist areas affected by intensification of tourism or overtourism, has changed from a positive or neutral vision to overt annoyance or irritation, which has generated a certain debate that has been conveyed in the media, an innovative aspect in the field of tourism. The term tourism phobia is mentioned for the first time in Spain linked to problems related to tourism and tourists. Donaire (Romero et al., 2019) specifically mentions the term tourism-phobia, referring to discontent in the latter stages in the Doxey's model (1975). Huete and Mantecón (2018) and Milano (2017, 2018) have linked tourism-phobia with a certain social opposition and criticism of tourist management. Milano (2018) describes that social criticism within a context of social organizations and residents outlining their disagreement with certain tourist activities. Huete and Mantecón (2018) coincides with Milano by pointing out that what the  media considers to be tourism-phobia is essentially a social critique of certain aspects of tourism. Other authors (Alcalde et al., 2018) highlight that the concept of tourism- phobia has been used in a misguided way, confusing the social discontent due to too many tourists with the rejection of them. Simultaneously and as opposed to the concept of tourism-phobia, the term tourism-philia arises, which refers to the perception of the positive effects of tourism on the local economy and society (Zerva et al., 2019).
  • 2.8K
  • 27 Oct 2020
Topic Review
Total/Subtotal Hysterectomy for the Treatment of Endometriosis
Hysterectomy is associated with risks; the risk of complications is greater in women with endometriosis. The majority of hysterectomies include removal of the cervix, but the rate of subtotal hysterectomies with retention of the cervical stump has increased in the last few decades.
  • 290
  • 07 Jun 2023
Topic Review
Total Joint Arthroplasty Failure
Total joint arthroplasty is a common restorative surgery. Arthroplasty failure is a major complication of joint replacement surgery. It can be caused by periprosthetic joint infection (PJI) or non-infectious etiologies, and often requires surgical intervention and (in select scenarios) resection and reimplantation of implanted devices. Fast and accurate diagnosis of PJI and non-infectious arthroplasty failure (NIAF) is critical to direct medical and surgical treatment.
  • 334
  • 13 Feb 2023
Topic Review
Total Endovascular Aortic Arch Repair
Aortic arch surgery is one of the most complex procedures in cardiac surgery. The gold-standard therapy for the treatment of aortic arch pathologies (including penetrating ulcers, intramural hematoma, aneurysms and pseudoaneurysms) remains open surgery performed under Cardiopulmonary Bypass (CPB) with hypothermic circulatory arrest and selective cerebral perfusion.
  • 398
  • 18 Mar 2022
Topic Review
Topoľčany Pogrom
The Topoľčany pogrom was an anti-Jewish riot in Topoľčany, Slovakia on 24 September 1945 and the best-known incident of post-Holocaust violence against Jews in Slovakia. The underlying cause was resurgent antisemitism directed at Jewish Holocaust survivors who demanded the return of property that had been stolen during the Holocaust. Rumors spread that a local Catholic school would be nationalized and the nuns who taught there replaced by Jewish teachers. On the morning of 24 September, women demonstrated against the nationalization of the school, blaming Jews. That same day, a Jewish doctor was vaccinating children at the school. He was accused of poisoning non-Jewish children, sparking a riot. The police were unable to prevent it, and a local garrison of soldiers joined in. About forty-seven Jews were injured, and fifteen had to be hospitalized. In the immediate aftermath of the events, international coverage embarassed the Czechoslovak authorities and the Czechoslovak Communist Party exploited the riots to accuse the democratic authorities of ineffectiveness. A 2004 documentary film about the rioting, Miluj blížneho svojho ("Love thy neighbor"), sparked increased discussion of the events. The next year, the mayor of Topoľčany issued an official apology.
  • 398
  • 28 Nov 2022
Topic Review
Topical Insulin Delivery
Insulin is one of the cheapest growth factors in the market able to accelerate the re-epithelialization and stimulate angiogenesis and cell migration. However, the effectiveness of topical insulin in wound healing is hampered by the proteases in the wound bed. The encapsulation into nanoparticles improves its stability in the wound, providing adhesion to the mucosal surface and allowing its sustained release. 
  • 724
  • 13 Sep 2021
Topic Review
Topical Cellular/Tissue and Molecular Aspects in Alzheimer’s Disease
One of the most complex and challenging developments at the beginning of the third millennium is the alarming increase in demographic aging, mainly—but not exclusively—affecting developed countries. This reality results in one of the harsh medical, social, and economic consequences: the continuously increasing number of people with dementia, including Alzheimer’s disease (AD), which accounts for up to 80% of all such types of pathology. Its large and progressive disabling potential, which eventually leads to death, therefore represents an important public health matter, especially because there is no known cure for this disease. Consequently, periodic reappraisals of different therapeutic possibilities are necessary. 
  • 148
  • 12 Dec 2023
Topic Review
Topical and Intradermal Administration in Horse
Horses are companion animals with temperamental and sensitive characteristics that play an important role in the lives of many individuals. Therefore, the global demand and market for equine healthcare products are rapidly increasing. However, comprehensive, and intensive information on drug development relating to equine health is still very much in its infancy. Delivering drugs to horses orally is a major challenge, as the physiology and anatomy of the equine gastro-intestinal tract (GIT) can result in poor bioavailability of some oral drugs. Additionally, due to their size, the dosages required are much larger and higher cost compared to those of humans; with potential of adverse effects, especially for antibiotics, following the administration of some drugs.
  • 400
  • 28 Jan 2023
Topic Review
Topical Agents for Nonrestorative Management of Dental Erosion
A nonrestorative approach to the management of dental erosion is the foremost option: controlling dental erosion. Nonrestorative approaches to dental erosion commonly include dietary analysis and counselling, oral health education and topical use of anti-erosive agents. Topical anti-erosive agents can be broadly categorised as fluorides, calcium phosphate-based agents, organic compounds and other anti-erosive agents. In the presence of saliva, fluorides promote the formation of fluorapatite on teeth through remineralisation.
  • 342
  • 11 Aug 2022
Topic Review
Toothpaste and Surface Roughness of Resin-Contained Dental Materials
Ceramic is the most used material for esthetic restorations in fixed prosthodontics. Surface roughness, translucency, resistance to wear, and mechanical properties are the main investigated characteristics of the ceramic surface. The surface roughness is one of the factors that influenced the clinical survival of prosthetic rehabilitation, optical properties, wear of the antagonist teeth, and initiation of cracks. Different factors influenced the surface roughness of the prosthetic materials, but the effect of brushing or polishing with toothpaste or prophylactic polishing pastes could be considered as one of the factors.
  • 481
  • 15 Feb 2022
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