Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Non-Calcified Coronary Artery Plaque on Coronary CT Angiogram
Coronary artery disease (CAD) is associated with increased mortality and morbidity and remains a great healthcare concern. Early detection of coronary artery plaque before its progression to calcification can allow early interventions towards regression. This will eventually translate into a lower incidence of future cardiovascular (CV) events. Dedicated and focused outcome-based research is highly indicated in this area to assess if there is utility of coronary computed tomography angiography (CCTA) in symptomatic and asymptomatic patients with zero or minimum coronary artery calcium score of zero (CACS). CCTA can be performed with minimal possible radiation exposure.
  • 517
  • 16 Oct 2023
Topic Review
Management of Obesity in Children and Adolescents
Obesity is a multifactorial chronic impairment that further decreases quality of life and life expectancy. Worldwide, childhood obesity has become a pandemic health issue causing several comorbidities that frequently present already in childhood, including cardiovascular (hypertension, dyslipidemia), metabolic (Type 2 diabetes mellitus, fatty liver disease, metabolic syndrome), respiratory, gastrointestinal and musculoskeletal disorders.
  • 222
  • 16 Oct 2023
Topic Review
COVID-19 Pandemic on Psychological Status in IBD Patients
The coronavirus disease (COVID-19) pandemic has had a considerable impact on the global healthcare system and potentially the clinical course of patients with inflammatory bowel disease (IBD). Although IBD is a chronic disease, its therapy (except steroid therapy) does not increase the risk of contracting or aggravating COVID-19.
  • 213
  • 16 Oct 2023
Topic Review
Non-Coding RNAs in Myelodysplastic Neoplasms
Myelodysplastic syndromes or neoplasms (MDS) are a heterogeneous group of myeloid clonal disorders characterized by peripheral blood cytopenias, blood and marrow cell dysplasia, and increased risk of evolution to acute myeloid leukemia (AML). Non-coding RNAs, especially microRNAs and long non-coding RNAs, serve as regulators of normal and malignant hematopoiesis and have been implicated in carcinogenesis.
  • 242
  • 16 Oct 2023
Topic Review
The Neural Correlates of Developmental Prosopagnosia
Faces play a crucial role in social interactions. Developmental prosopagnosia (DP) refers to the lifelong difficulty in recognizing faces despite the absence of obvious signs of brain lesions. In recent decades, the neural substrate of this condition has been extensively investigated. While early neuroimaging studies did not reveal significant functional and structural abnormalities in the brains of individuals with developmental prosopagnosia (DPs), the evidence identifies abnormalities at multiple levels within DPs’ face-processing networks. 
  • 206
  • 16 Oct 2023
Topic Review
Psittacosis
The bacterial agent Chlamydia psittaci, and the resulting disease of psittacosis, is a little-known and underappreciated infectious disease by healthcare practitioners and in public health in general. C. psittaci infections can cause significant psittacosis outbreaks with pandemic potential, with person-to-person transmission being documented in the last decade.
  • 229
  • 16 Oct 2023
Topic Review
Hypercoagulability in End-Stage Liver Disease
End-stage liver disease (ESLD) is associated with significant changes in a patient’s coagulation profile. These changes are unique in that they involve all branches of the coagulation system. The hypercoagulability is associated with significant endothelial dysfunction (ED) due to nitric oxide dysregulation.
  • 338
  • 16 Oct 2023
Topic Review
Molecular Mechanisms of Anthracycline-Induced Cardiotoxicity
Anthracycline is identified as one of the cancer treatments most likely to induce a significant decrease in left ventricular (LV) ejection fraction (LVEF), cardiomyopathy, and cardiac ischemia, ultimately leading to heart failure.
  • 324
  • 16 Oct 2023
Topic Review
Biomarkers in Inflammatory Bowel Disease
The role of biomarkers in the diagnosis of inflammatory bowel disease is not fully characterized. C-reactive protein has a short half-life and elevates quickly after the onset of an inflammatory process; the performance is better in Crohn’s disease than in ulcerative colitis. Erythrocyte sedimentation rate is easy to determine, widely available, and cheap, but the long half-life, the influence of age, anemia, smoking, and drugs limit its usefulness. Fecal markers have good specificity, but suboptimal accuracy. Microbial antibodies and novel immunological markers show promise but need further evidence before entering clinical practice. Proteomic methods could represent the dawn of a new era of stool protein/peptide biomarker panels able to select patients at risk of inflammatory bowel disease.
  • 225
  • 16 Oct 2023
Topic Review
Acquired Isolated Factor VII Deficiency in Plasma Cell
Acquired isolated factor VII (FVII) deficiency is a rare but important discovery in patients with plasma cell disorders with significant therapeutic and prognostic implications. The discovery of acquired FVII deficiency in a patient with multiple myeloma (MM) or monoclonal gammopathy of uncertain significance (MGUS) should prompt an evaluation for AL amyloidosis, particularly for amyloid hepatosplenic involvement, whenever not previously documented. Acquired FVII deficiency in patients with MM and AL amyloidosis is frequently associated with severe bleeding diathesis, also related to a number of concomitant predisposing factors, adversely affecting the outcome. The prompt institution of a rapidly acting therapy is crucial to prevent severe bleeding complications and positively impact outcome. Recombinant activated factor VII (rVIIa) may represent a useful supportive care measure, both in treating active bleeding and in the peri-procedural setting. However, further clinical experience is needed to optimize the therapeutic management of this rare disorder.
  • 149
  • 16 Oct 2023
  • Page
  • of
  • 1349
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Video Production Service
Feedback