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Topic Review
Short-Chain Fatty Acids
The relationship between diet and the diversity and function of the intestinal microbiome and its importance for human health is currently the subject of many studies. The type and proportion of microorganisms found in the intestines can determine the energy balance of the host. Intestinal microorganisms perform many important functions, one of which is participation in metabolic processes, e.g., in the production of short-chain fatty acids—SCFAs (also called volatile fatty acids). These acids represent the main carbon flow from the diet to the host microbiome. Maintaining intestinal balance is necessary to maintain the host’s normal health and prevent many diseases. The results of many studies confirm the beneficial effect of probiotic microorganisms on the balance of the intestinal microbiome and produced metabolites, including SCFAs. The aim of this review is to summarize what is known on the effects of probiotics on the production of short-chain fatty acids by gut microbes. In addition, the mechanism of formation and properties of these metabolites is discussed and verified test results confirming the effectiveness of probiotics in human nutrition by modulating SCFAs production by intestinal microbiome is presented.
  • 4.2K
  • 30 Oct 2020
Topic Review
Fly Ash
Fly ash or coal fly ash causes major global pollution in the form of solid waste and is classified as a “hazardous waste”, which is a by-product of thermal power plants produced during electricity production. Si, Al, Fe Ca, and Mg alone form more than 85% of the chemical compounds and glasses of most fly ashes. Fly ash has a chemical composition of 70–90%, as well as glasses of ferrous, alumina, silica, and CaO. Therefore, fly ash could act as a reliable and alternative source for ferrous, alumina, and silica. The ferrous fractions can be recovered by a simple magnetic separation method, while alumina and silica can be extracted by chemical or biological approaches. Alumina extraction is possible using both alkali- and acid-based methods, while silica is extracted by strong alkali, such as NaOH. Chemical extraction has a higher yield than the biological approaches, but the bio-based approaches are more environmentally friendly. Fly ash can also be used for the synthesis of zeolites by NaOH treatment of variable types, as fly ash is rich in alumino-silicates. The present review work deals with the recent advances in the field of the recovery and synthesis of ferrous, alumina, and silica micro and nanoparticles from fly ash.
  • 3.9K
  • 06 Apr 2021
Topic Review
Microbial Interactions in Nature
Microorganisms like bacteria, archaea, fungi, microalgae, and viruses mostly form complex interactive networks within the ecosystem rather than existing as single planktonic cells. Interactions among microorganisms occur between the same species, with different species, or even among entirely different genera, families, or even domains. These interactions occur after environmental sensing, followed by converting those signals to molecular and genetic information, including many mechanisms and classes of molecules. Comprehensive studies on microbial interactions disclose key strategies of microbes to colonize and establish in a variety of different environments. Knowledge of the mechanisms involved in microbial interactions is essential to understand the ecological impact of microbes and the development of dysbioses. Furthermore, it might be the key to exploit strategies and specific agents against different facing challenges, such as chronic and infectious diseases, hunger crisis, pollution, and sustainability.
  • 3.8K
  • 18 Jun 2021
Topic Review
16S rRNA Next-Generation Sequencing
The 16S rRNA gene is highly conserved in all bacteria (and also archaea). Nonetheless, it contains nine hypervariable regions (V1 - V9), where sequences of these regions can be used to identify and discriminate bacterial genus, sometimes until the species level. This makes the gene a useful tool for phylogenetic studies. With the introduction of next-generation sequencing technologies, 16S rRNA next-generation sequencing (16SNGS) has allowed profiling of bacterial communities found in organisms and the environment, and lead to the discovery of many previously unculturable members of the bacteria kingdom.
  • 3.7K
  • 18 May 2021
Topic Review
Dry Sanitation Systems
Dry sanitation systems (waterless or composting toilets) have been used since the 1970s. Their use has received acceptance in rural regions of Europe and the United States. Some of the advantages of dry sanitation systems include their waterless nature, their low energy requirement and the creation of fertilizer as an added value product. Moreover, the use of such a system is a sustainable sanitation approach that may reduce the burden on infrastructure and provide sanitation to the 2.5 billion people worldwide who do not currently have access to it. The critical factors when choosing a dry sanitation system and their optimum parameters include aeration, moisture content (50%–60%), temperature (40–65 °C), carbon to nitrogen ratio (25–35), pH (5.5–8.0) and porosity (35%–50%). The temperature–time criterion approach is the most common method used to evaluate the stability and safety of the compost as a fertilizer. The risks of handling the waste after 12 months of composting have been calculated as low.
  • 3.6K
  • 27 Oct 2020
Topic Review
Cyberlindnera jadinii
Cyberlindnera jadinii is widely used as a source of single-cell protein and is known for its ability to synthesize a great variety of valuable compounds for the food and pharmaceutical industries. Its capacity to produce compounds such as food additives, supplements, and organic acids, among other fine chemicals, has turned it into an attractive microorganism in the biotechnology field.
  • 3.5K
  • 04 Oct 2021
Topic Review
Corynebacterium
Corynebacterium species are frequent constituents of the normal bacterial flora of the conjunctival sac and are common as well on human skin and mucous membranes and in the intestines.
  • 3.2K
  • 18 Mar 2021
Topic Review
Myocyte
A myocyte (also known as a muscle cell) is the type of cell found in some types of muscle tissue. Myocytes develop from myoblasts to form muscles in a process known as myogenesis. There are two specialized forms of myocytes with distinct properties: cardiac, and smooth muscle cells. On the other hand, skeletal muscles are formed by morphological units referred to as muscle fibers. Cardiomyocytes are the cells that form the chambers of the heart, and have a single central nucleus. Skeletal muscle fibers help support and move the body and are called syncytia – multinucleated structures formed by fusion of individual myoblasts during embryonic development. Smooth muscle cells control involuntary movements such as the peristalsis contractions in the oesophagus and stomach.
  • 3.1K
  • 25 Oct 2022
Topic Review
Polyenes
Polyenes were, after griseofulvin, the first fungal-specific antibiotics on the market and ever since, more than 200 polyene antifungals have been discovered, of which amphotericin B, nystatin and natamycin are most commonly used in antifungal therapy .
  • 2.7K
  • 12 Jan 2021
Topic Review
Biocontrol Agents
Biocontrol agents (BCAs) are living organisms and their derivatives that act against plant diseases and pests via direct antagonistic effects but also indirectly via the induction of plant resistance. They have been proposed as an alternative to standard fungicides but their disease management capacity is usually incomplete and heavily relies on uncontrollable environmental conditions. An integrated approach of combining BCAs with fungicides can reduce the fungicide doses to manage plant diseases and thereby their residual effects that affect the environment and human health.
  • 2.7K
  • 16 Dec 2020
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