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Topic Review
Plasmonic Substrates for MicroRNA Delivery
MicroRNA (miRNA) has emerged as a promising alternative therapeutic treatment for cancer, but its delivery has been hindered by low cellular uptake and degradation during circulation.
  • 422
  • 25 May 2023
Topic Review
History of Cellulose in Science and Technology
In the history of cellulose chemistry, hydrogen bonding has been the predominant explanation when discussing intermolecular interactions between cellulose polymers. This is unfortunately the general consensus in scholarly textbooks and in many research articles, and it applies to several other biomacromolecules’ interactions as well. The amphiphilicity of cellulose and many other biopolymers, and thereby hydrophobic interactions, has to be taken into account to get a more complete picture.
  • 413
  • 25 May 2023
Topic Review
Manufacturing Techniques of IOT Hybrid Fiber Materials
The fabrication of smart fabrics can be divided into coating and lamination processes. Coating methods include dip, knife or blade, air knife, metering rod, transfer, roll, paste dot, and powder. Laminating methods include flame, wet adhesive, hot melt, dry heat, and ultrasonic. Flame lamination is a process in which a prepared thin thermoplastic foam sheet is passed over an open flame to generate a thin layer of a molten polymer. Polyurethane foam (PUF) is the most frequently used foam. Wet adhesives used in the laminating process are either water- or solvent-based. They are applied to the substrate surface in liquid form using conventional coating methods, such as gravure roll coating, spraying, roll coating, and knife coating. Then, the adhesive-coated web is bonded with other substrates under pressure and dried or cured in an oven.
  • 232
  • 24 May 2023
Topic Review
Synthetic Methodologies of Indole-3-Carbinol
Indole-3-Carbinol (I3C)  is an important phytochemical contained in cruciferous vegetables and is able to exert various activities among which are cardioprotective, antioxidant, anti-inflammatory, antiangiogenesis, and antimicrobial activities, the promotion of tumor cell apoptosis and, an important inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS)-CoV-2 viral egression, including the Omicron variant.
  • 472
  • 24 May 2023
Topic Review
Fireproof Nanocomposite Polyurethane Foams
First introduced in 1954, polyurethane foams rapidly became popular because of light weight, high chemical stability, and outstanding sound and thermal insulation properties. Currently, polyurethane foam is widely applied in industrial and household products. Despite tremendous progress in the development of various formulations of versatile foams, their use is hindered due to high flammability. Fire retardant additives can be introduced into polyurethane foams to enhance their fireproof properties. Nanoscale materials employed as fire-retardant components of polyurethane foams have the potential to overcome this problem.
  • 244
  • 24 May 2023
Topic Review
Structure and Properties of Gelatin
Gelatin is a natural biopolymer that is intrinsically biocompatible and biodegradable, has low immunogenicity, and is classified as Generally Recognized as Safe (GRAS) by the United States Food and Drug Administration (FDA). It consists of an amphoteric polymer that is derived from collagen by alkaline-, acid-, or heat-based hydrolysis.
  • 15.8K
  • 24 May 2023
Topic Review
Sample Preparation for Benzophenone Detection
The benzophenones (BPs) constitute a group of compounds belonging to waterborne pollutants of emerging concern, which have been identified in the environment as well as in human fluids, such as urine, placenta, and breast milk, with the chemical formula (C6H5)2CO or Ph2CO. They consist of two phenyl groups linked to a carbonyl group. Their accumulation and stability in the environment, combined with the revealed adverse effects on ecosystems including endocrine, reproductive, and other disorders, have triggered significant interest for research. Benzophenones should be extracted from environmental samples and determined for environmental-monitoring purposes to assess their presence and possible dangers. Numerous sample preparation methods for benzophenones in environmental matrices and industrial effluents have been proposed and their detection in more complex matrices, such as fish and sludges, has also been reported. These methods range from classical to more state-of-the-art methods, such as solid-phase extraction, dispersive SPE, LLE, SBSE, etc., and the analysis is mostly completed with liquid chromatography, using several detection modes.
  • 405
  • 23 May 2023
Topic Review
Chemical Recycling for Plastic Waste
Plastics play an integral role in shaping our modern society and are ubiquitous in our daily lives. Their superior material characteristics, performance, and low production cost make them desirable for vast consumer and industrial applications. Chemical or feedstock recycling refers to any reprocessing technology directly affecting the formulation of polymeric waste or the polymer itself.  The recycling plastic waste through chemical means are explored.
  • 416
  • 23 May 2023
Topic Review
Mucoadhesive and Mucopenetrating Polymer-Based Adjuvants
Mucus is a viscoelastic gel that acts as a protective barrier for epithelial surfaces. The mucosal vehicles and adjuvants need to pass through the mucus layer to make drugs and vaccine delivery by mucosal routes possible. The mucoadhesion of polymer particle adjuvants significantly increases the contact time between vaccine formulations and the mucosa; then, the particles can penetrate the mucus layer and epithelium to reach mucosa-associated lymphoid tissues.
  • 352
  • 23 May 2023
Topic Review
Proteolysis-Targeting Chimeras
The ubiquitin–proteasome system (UPS) is an essential part of the cellular machinery responsible for maintaining intracellular protein homeostasis. A network of proteins that comprises the proteolytic system and chaperones calculates cellular protein homeostasis. Chaperones are in charge of correcting protein misfolding, but the proteolytic system, which converges on the 26S proteasome, is in charge of removing damaged or unfolded proteins to maintain a healthy environment inside the cell. Using proteolysis-targeting chimera (PROTAC) technology for targeted protein degradation, a novel technique of treatment is emerging that stems from an aberrant expression of a protein that causes disease. PROTAC molecules are tiny, bifunctional molecules that bind an E3-ubiquitin ligase and a target protein at the same time, causing ubiquitination and proteasome destruction of the target protein.
  • 556
  • 22 May 2023
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