Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Boron Chemicals
Boron-based bioactive compounds have provided amphiphilic properties to facilitate interaction with protein targets. Indeed, the spectrum of boron-based entities as drug candidates against many diseases has grown tremendously since the first clinically tested boron-based drug, Velcade. 
  • 878
  • 27 Apr 2022
Topic Review
Boron Nitride Materials
Boron nitride 2D materials are characterized by several defects which affect their optical properties. A better in-sight of the structure is achieved by theoretical calculations which have been used to investigate the boron-nitride defects and their functionalization on the atomic scale. A brief overview of the main theoretical models used to describe the defects-properties relationship is given in the present entry.
  • 959
  • 26 Oct 2020
Topic Review
Boron Used in Lithium Batteries Electrolytes
Boron and boron compounds have been extensively studied together in the history and development of lithium batteries, which are crucial to decarbonization in the automotive industry and beyond. As early as the year 2000, lithium bis(oxalato)borate, also known as LiBOB, was first reported for synthesis and use in electrolytes of LIBs. Because of the merits of being halide-free and more thermally stable than LiPF6, LiBOB has been proven beneficial either as a direct replacement for LiPF6 or as an electrolyte additive (2 wt%) in a nickel cobalt aluminum (NCA)—graphite system.
  • 1.1K
  • 03 Nov 2022
Topic Review
Boron Vehiculating Nanosystems in Cancer Treatment
Boron neutron capture therapy is a low-invasive cancer therapy based on the neutron fission process that occurs upon thermal neutron irradiation of 10B-containing compounds; this process causes the release of alpha particles that selectively damage cancer cells. Although several clinical studies involving mercaptoundecahydro-closo-dodecaborate and the boronophenylalanine–fructose complex are currently ongoing, the success of this promising anticancer therapy is hampered by the lack of appropriate drug delivery systems to selectively carry therapeutic concentrations of boron atoms to cancer tissues, allowing prolonged boron retention therein and avoiding the damage of healthy tissues. To achieve these goals, numerous research groups have explored the possibility to formulate nanoparticulate systems for boron delivery. Here the researchers report the newest developments on boron vehiculating drug delivery systems based on nanoparticles, distinguished on the basis of the type of carrier used, with a specific focus on the formulation aspects.
  • 459
  • 21 Dec 2022
Topic Review
Boron-Silicon Junction
The discovery of the extremely shallow amorphous boron-crystalline silicon heterojunction occurred during the development of highly sensitive, hard and robust detectors for low-penetration-depth ionizing radiation, such as ultraviolet photons and low-energy electrons (below 1 keV). For many years it was believed that the junction created by the chemical vapor deposition of amorphous boron on n-type crystalline silicon was a shallow p-n junction, although experimental results could not provide evidence for such a conclusion. Only recently, quantum-mechanics based modelling revealed the unique nature and the formation mechanism of this new junction. Here, the entry reviews the initiation and the history of understanding the a-B/c-Si interface (henceforth called the “boron-silicon junction”).
  • 1.5K
  • 17 Jun 2021
Topic Review
Botanicals in Postmenopausal Osteoporosis
Osteoporosis is a systemic bone disease characterized by reduced bone mass and the deterioration of bone microarchitecture leading to bone fragility and an increased risk of fractures. Conventional anti-osteoporotic pharmaceutics are effective in the treatment and prophylaxis of osteoporosis, however they are associated with various side effects that push many women into seeking botanicals as an alternative therapy. 
  • 665
  • 02 Jun 2021
Topic Review
Bound Water and Tissue Stiffness
The mechanical properties of living biological tissues change with aging and commonly can be associated with age-related diseases. Increase of tissue stiffness can be related also with thermodynamically favorable release of tightly bound to biological macromolecules water molecules. 
  • 1.6K
  • 10 Aug 2020
Topic Review
BPA Controversy
Bisphenol A controversy centers on concerns and debates about the biomedical significance of bisphenol A (BPA), which is a precursor to polymers that are used in some consumer products, including some food containers. The concerns began with the hypothesis that BPA is an endocrine disruptor, i.e. it mimics endocrine hormones and thus has the unintended and possibly far-reaching effects on people in physical contact with the chemical. Since 2008, several governments have investigated its safety, which prompted some retailers to withdraw polycarbonate products. The U.S. Food and Drug Administration (FDA) ended its authorization of the use of BPA in baby bottles and infant formula packaging, based on market abandonment, not safety. The European Union and Canada have banned BPA use in baby bottles. The U.S. FDA states "BPA is safe at the current levels occurring in foods" based on extensive research, including two more studies issued by the agency in early 2014. The European Food Safety Authority (EFSA) reviewed new scientific information on BPA in 2008, 2009, 2010, 2011 and 2015: EFSA's experts concluded on each occasion that they could not identify any new evidence which would lead them to revise their opinion that the known level of exposure to BPA is safe; however, the EFSA does recognize some uncertainties, and will continue to investigate them. In February 2016, France announced that it intends to propose BPA as a REACH Regulation candidate substance of very high concern (SVHC). The European Chemicals Agency agreed to the proposal in June 2017.
  • 1.5K
  • 11 Oct 2022
Topic Review
Brass Alloys against Hospital-Acquired Infections
Touch surfaces made of copper-based alloys such as brasses are used in healthcare settings in an attempt to reduce the bioburden and limit environmental transmission of nosocomial pathogens. 
  • 1.2K
  • 22 Apr 2021
Topic Review
Brassica Bioactives on Human Health
Brassica vegetables and their components, the glucosinolates, have been suggested as good candidates as dietary coadjutants to improve health in non-communicable diseases (NCDs).
  • 453
  • 12 Nov 2021
  • Page
  • of
  • 467
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Video Production Service
Feedback