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Topic Review
Biography
Topic Review
Electrospun Nanofibers: Basic Principles
Electrospun nanofibers had been gaining importance in several areas such as the biomedical, environmental, food, textile, and biotechnology industries, amongst others. The fabrication of three-dimensional membranes through the electrospinning technique confers several characteristics that are important in the above industrial approaches such as high-to-volume radio, high surface area, controllable porosity, thickness, and mechanical properties, also the non-toxicity, biocompatibility, and biodegradability can be conferred to the scaffolds by choosing the adequate polymeric formulation. This entry discusses the characteristics and importance of electrospun nanofibers in industry.
2.6K
13 Aug 2021
Topic Review
Low Molecular Weight Chitosan
Chitosan is a biopolymer with high added value, and its properties are related to its molecular weight. Thus, high molecular weight values provide low solubility of chitosan, presenting limitations in its use. Based on this, several studies have developed different hydrolysis methods to reduce the molecular weight of chitosan.
2.4K
13 Aug 2021
Topic Review
Applications of AMPs in Packaging
Antimicrobial Peptides can be defined as the molecules of the innate immune system present in all life forms, ranging from bacteria to human beings. The innate immune system is a defence system working non-specifically against injury or infection in the barrier surface. AMPs are composed of a sequence of amino acid ranging from 5 to 50 chains, usually L-amino acids.
868
13 Aug 2021
Topic Review
Salvigenin
Phytochemical analysis of the Iranian plant Achillea wilhelmsii led to the isolation of 17 pure secondary metabolites belonging to the classes of sesquiterpenoids and phenolics. Two of these compounds, named wilhemsin (7) and wilhelmsolide (9), are new sesquiterpenoids, and the first shows undescribed structural features. Their structures were elucidated through extensive spectroscopic analysis, mainly based on 1D and 2D NMR, and chemical derivatization. Starting from plant traditional use and previous reports on the activity of the plant extracts, all the pure compounds were evaluated on endpoints related to the treatment of metabolic syndrome. The sesquiterpene hanphyllin (8) showed a selective cholesterol-lowering activity (−12.7% at 30 µM), santoflavone (13) stimulated glucose uptake via the GLUT transporter (+16.2% at 30 µM), while the trimethoxylated flavone salvigenin (14) showed a dual activity in decreasing lipid levels (−22.5% palmitic acid biosynthesis at 30 µM) and stimulating mitochondrial functionality (+15.4% at 30 µM).
692
13 Aug 2021
Topic Review
Economic Friendly ZnO-Based UV Sensors
Ultraviolet (UV) sensors offer significant advantages in human health protection and environmental pollution monitoring. Amongst various materials for UV sensors, the zinc oxide (ZnO) nanostructure is considered as one of the most promising candidates due to its incredible electrical, optical, biomedical, energetic and preparing properties. Compared to other fabricating techniques, hydrothermal synthesis has been proven to show special advantages such as economic cost, low-temperature process and excellent and high-yield production.
473
13 Aug 2021
Topic Review
Fluorescent Materials for Mitochondrial Biology
Mitochondria are double-membraned organelles. The mitochondrial inner membrane has characteristic folds, called cristae, providing a large amount of surface area for chemical reactions, and it is enclosed by a permeable mitochondrial outer membrane, which completes the double membrane-bound architecture of mitochondria. Mitochondria undergo dynamic movement inside cells by fusion and fission and build large interconnected intracellular networks, a process which is called mitochondrial dynamics.
650
12 Aug 2021
Topic Review
Dimensionality of materials
As generally known dimensionality of materials is a crucial factor to determine functions and properties of the materials. In addition to zero-dimensional, one-dimensional, three-dimensional, and further integrated functional materials, various two-dimensional materials have been paid special attention. Two-dimensional materials have their unique electronic propertiesand play important roles in interfacial sciences.
2.3K
12 Aug 2021
Topic Review
Natural-Drugs-Based Low-Molecular-Weight Supramolecular Gels
The utilization of paclitaxel, camptothecin, rhein, curcumin, and other natural small molecular drugs with unique rigid backbone structures and modifiable multiple sites as building blocks to form gels by self-assembly has attracted widespread attention. The obtained low-molecular-weight supramolecular gel not only retains the general characteristics of the gel but also overcomes the shortcomings of natural drugs, such as poor water solubility and low bioavailability.
1.0K
12 Aug 2021
Topic Review
Nanocarbon-Based Flame Retardant Polymer Nanocomposites
Nanocarbon materials have attracted the interest of researchers due to their excellent properties. Nanocarbon-based flame retardant polymer composites have enhanced thermal stability and mechanical properties compared with traditional flame retardant composites.
715
12 Aug 2021
Topic Review
Renal Nanomedicine
The kidneys are vital organs performing several essential functions. Their primary function is the filtration of blood and the removal of metabolic waste products as well as fluid homeostasis. Renal filtration is the main pathway for drug removal, highlighting the importance of this organ to the growing field of nanomedicine. The kidneys (i) have a key role in the transport and clearance of nanoparticles (NPs), (ii) are exposed to potential NPs’ toxicity, and (iii) are the targets of diseases that nanomedicine can study, detect, and treat.
889
12 Aug 2021
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