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Topic Review
Design of Magnetic Nanoplatforms for Cancer Theranostics
Cancer is the top cause of death globally. Developing smart nanomedicines that are capable of diagnosis and therapy (theranostics) in one–nanoparticle systems are highly desirable for improving cancer treatment outcomes. The magnetic nanoplatforms are the ideal system for cancer theranostics, because of their diverse physiochemical properties and biological effects. In particular, a biocompatible iron oxide nanoparticle based magnetic nanoplatform can exhibit multiple magnetic–responsive behaviors under an external magnetic field and realize the integration of diagnosis (magnetic resonance imaging, ultrasonic imaging, photoacoustic imaging, etc.) and therapy (magnetic hyperthermia, photothermal therapy, controlled drug delivery and release, etc.) in vivo. Furthermore, due to considerable variation among tumors and individual patients, it is a requirement to design iron oxide nanoplatforms by the coordination of diverse functionalities for efficient and individualized theranostics. 
  • 415
  • 03 Mar 2022
Topic Review
Sweet Boron
Boron neutron capture therapy (BNCT) is a binary type of radiotherapy for the treatment of cancer. Due to recent developments of neutron accelerators and their installation in some hospitals, BNCT is on the rise worldwide and is expected to have a significant impact on patient treatments. Therefore, there is an increasing need for improved boron delivery agents. 
  • 601
  • 03 Mar 2022
Topic Review
Gluten Conformation at Different Temperatures and Additive Treatments
The effect of temperature (25, 45, and 65 °C) on the gluten secondary structure was investigated by using Fourier transform infrared (FTIR) spectroscopy and modulation of disulfide and hydrogen bonds contributions (100 ppm ascorbic acid (AA), 0.6% diacetyl tartaric acid ester of monoglycerides (DATEM), and 0.25 mM dithiothreitol (DTT)). The results showed that additives heated at 65 °C altered most of the gluten matrix formation by changing structural secondary structures compared to the secondary structures of native gluten (control). The content of random coils, α-helices, and β-sheet of gluten increased, while the extent of β-turns and antiparallel β-sheets decreased, which led to the transformation to a more stable secondary conformation. In addition, the rheological properties (%creep strain) revealed that gluten deformation increased during the heating process with all of the additives. The chemometric method could quantitate an overall alteration of gluten polymerization and gluten matrix formation during heating with additive treatments. 
  • 856
  • 03 Mar 2022
Topic Review
Enriching WPCs and NFPCs with Carbon Nanomaterials
Carbon nanotubes (CNTs) and graphene, with their unique mechanical, electrical, thermal, optical, and wettability properties, are very effective fillers for many types of composites. Recently, a number of studies have shown that CNTs and graphene may be integrated into wood–plastic composites (WPCs) and natural-fibre-reinforced polymer composites (NFPCs) to improve the existing performance of the WPCs/NFPCs as well as enabling their use in completely new areas of engineering. 
  • 513
  • 02 Mar 2022
Topic Review
Plant-Mediated Nanoparticle Synthesis
The green synthesis of nanoparticles(NPs) is gaining attention owing to its facilitation of the development of alternative, sustainable, safer, less toxic and environment-friendly approaches. Thus, green nanotechnology using plant extract opens up new possibilities for the synthesis of novel nanoparticles with the desirable characteristics required for developing biosensors, biomedicine, cosmetics and nano-biotechnology, and in electrochemical, catalytic, antibacterial, electronics, sensing and other applications. 
  • 3.4K
  • 02 Mar 2022
Topic Review
Liquid Chromatography Separation Mechanism
Separation is a critical process to isolate a particular compound, whether it is a natural product or a synthetic product. Studies of a compound’s characteristics and elucidation structure provides reliable results for pure compounds because there is no interference from other compounds. The primary source of difficulty in a separation process is the high similarity between two or more compounds, such as racemic and homologous mixtures. Liquid chromatography has proven to be an effective solution to those problems. The key to liquid chromatography separation is a sustainable retention and elution process. Stationary phases are essential for separating compounds in liquid chromatography. Various liquid chromatography columns of both preparative and quantitative types have been used and continue to develop. This research will discuss the separation mechanism in liquid chromatography.
  • 678
  • 02 Mar 2022
Topic Review
Lipsticks History, Formulations, and Production
Lipsticks are one of the most widely used cosmetic products. Social, psychological, and therapeutic benefits can be attained from using lipstick. The beauty and attractiveness of a person are enhanced as lipsticks colour the lips and protect them from the external environment.
  • 4.9K
  • 02 Mar 2022
Topic Review
Pancreatic Cancer Treatment by Nab-Paclitaxel with Gemcitabine Combination
Pancreatic cancer has one of the highest mortality rates among cancers, and a combination of nab-paclitaxel with gemcitabine remains the cornerstone of first-line therapy. Nab-paclitaxel with gemcitabine in combination with other therapeutic agents can be new treatment strategies in pancreatic cancer. Seven therapeutic agents (ibrutinib, necuparanib, tarextumab, apatorsen, cisplatin, enzalutamide, and momelotinib) are found. 
  • 615
  • 01 Mar 2022
Topic Review
Technological Uses of Thioketal in Drug Delivery Systems
To take advantage of ROS-specific cleavage, different technological uses of Thioketal (TK) functional group have been proposed in the design of selective and improved “smart” nanosystems, including as linker to connect a drug on the surface of nanoparticles, form prodrugs, as a core component of the Drug Delivery System (DDS) to directly control its structure, to control the opening of drug-releasing gates or to change the conformation of the nano-systems. This allows to overcome the major limitations of conventional DDS counterparts, including uncontrolled drug release and off-target effects, by controlling the degradation kinetics, drug release kinetics, or even increasing potential administration routes. 
  • 706
  • 01 Mar 2022
Topic Review
T-MIR Spectroscopy Applications in Coffee and Cocoa
Nowadays, coffee and cocoa have broad applications in the food and pharmaceutical industries due to their organoleptic and nutraceutical properties, which have turned them into products of great commercial demand. Consequently, these products are susceptible to fraud and adulteration, especially those sold at high prices, such as saffron, vanilla, and turmeric. This situation represents a major problem for industries and consumers’ health. Implementing analytical techniques, i.e., Fourier transform mid-infrared (FT-MIR) spectroscopy coupled with multivariate analysis, can ensure the authenticity and quality of these products since these provide unique information on food matrices.
  • 476
  • 01 Mar 2022
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