Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Chitosan-Based Electrochemical Sensors for Pharmaceuticals Detection
This research explores advances in the detection and quantification of pharmaceutical substances, with a focus on the development of high-performance electrochemical sensors, particularly those based on chitosan, to address the need for sensitive and selective detection techniques in various applications.
  • 1.2K
  • 07 Sep 2023
Topic Review
Alzheimer's disease
Alzheimer's disease (AD) is a multifactorial disease and the most common neurodegenerative disorder affecting the elderly population world-wide.The used medications treat the symptoms of AD, but without any delay on the progression of the disease. Curcumin presented favorable effects on AD. In the last decade curcumin analogues and derivatives have been synthesized in an attempt to optimize the beneficial properties of curcumin and improve its absorbance and  distribution per os as a therapeutic agent. Reviewing the bibliographical data of the last decade, information on the structures and / or chemical groups that are associated with specific action against AD, was gathered, derived from docking studies, (Q)SAR from vitro and in vivo tests. Phenolic hydroxyl groups might contribute to the anti-amyloidogenic activity. Phenyl methoxy groups seems to contribute to the suppression of Aβ42 and to the suppression of APP. Hydrophobic interactions revealed to be important. The presence of flexible moieties at the linker are crucial for the inhibition of Aβ aggregation. The inhibitory activity of derivatives is increased with the expansion of the aromatic rings. The keto-enol tautomer form offers as a new modification for the design of amyloid-binding agents. Taking the above under consideration  innovative design  and synthesis will lead to more potent and specific curcumin analogues and derivatives against AD.
  • 1.2K
  • 30 Oct 2020
Topic Review
Naringin
Polyphenols comprise a number of natural substances, such as flavonoids, that show interesting biological effects. Among these substances is naringin, a naturally occurring flavanone glycoside found in citrus fruits and Chinese medicinal herbs. Several studies have shown that naringin has numerous biological properties, including cardioprotective, cholesterol-lowering, anti-Alzheimer’s, nephroprotective, antiageing, antihyperglycemic, antiosteoporotic and gastroprotective, anti-inflammatory, antioxidant, antiapoptotic, anticancer and antiulcer effects. Despite its multiple benefits, the clinical application of naringin is severely restricted due to its susceptibility to oxidation, poor water solubility, and dissolution rate.
  • 1.2K
  • 24 Mar 2023
Topic Review
Moist Rice Husk Smoldering for Silica Production
In order to assess the possibility of silica production via smoldering of moist rice husk, experiments of washed (moist) rice husk (7 kg with moisture content of 51%) in a newly designed smoldering apparatus was performed. The temperature inside the fuel bed during smoldering was recorded, and characteristics of ash were analyzed. Results showed that the highest temperature in the middle of the naturally piled fuel bed was about 560.0 °C, lower than those in most of combustors. Some volatiles from the lower part of the fuel bed adhere to its upper ash during piled smoldering. Silica content and specific surface area of ash from smoldering of washed (moist) rice husk were 86.4% and 84.9 m2/g, respectively.
  • 1.2K
  • 24 Jan 2022
Topic Review
Nanomaterials in Cosmetic
Skin aging is described as dermatologic changes either naturally occurring over the course of years or as the result of the exposure to environmental factors (e.g., chemical products, pollution, infrared and ultraviolet radiations). The production of collagen and elastin, the main structural proteins responsible for skin strength and elasticity, is reduced during aging, while their role in skin rejuvenation can trigger a wrinkle reversing effect. Elasticity loss, wrinkles, dry skin, and thinning are some of the signs that can be associated with skin aging. To overcome skin aging, many strategies using natural and synthetic ingredients are being developed aiming to reduce the signs of aging and/or to treat age-related skin problems (e.g., spots, hyper- or hypopigmentation). Among the different approaches in tissue regeneration, the use of nanomaterials loaded with cosmeceuticals (e.g., phytochemicals, vitamins, hyaluronic acid, and growth factors) has become an interesting alternative. Based on their bioactivities and using different nanoformulations as efficient delivery systems, several cosmeceutical and pharmaceutical products are now available on the market aiming to mitigate the signs of aged skin.
  • 1.2K
  • 30 Oct 2020
Topic Review
{001} Faceted Anatase TiO2-Based Composites
For anatase TiO2, the {001} crystal facets are the most reactive because they exhibit unique surface characteristics such as visible light responsiveness, dissociative adsorption, efficient charge separation capabilities and photocatalytic selectivity. In this review, a concise survey of the literature in the field of {001} dominated anatase TiO2 crystals and their composites is presented. Even though the design and morphologically controlled synthesis of TiO2-001 is considered to be a hot spot in scientific research, it still has some drawbacks like its wide band gap and high recombination rate. These drawbacks can easily be overcome by coupling them with other materials to form TiO2-001-based composites. This review focusses on the synthesis, properties and applications of TiO2-001-based composites. 
  • 1.2K
  • 12 Nov 2021
Topic Review
Functional Materials for Wearable Sensors
With the recent development of flexible electronic materials, smart transducers, and wireless systems, wearable sensor technology has gained significant interest in the realization of personalized medical care. The design and development of flexible/stretchable dry electrodes with good adherence to biological tissues is in great demand due to the complex attributes of the human body. However, the major difficulty is finding the appropriate materials with good flexibility and conductivity, although some other relevant features such as bio-compatibility, durability, weight, size, etc.
  • 1.2K
  • 05 Sep 2022
Topic Review
Natural Clinoptilolite
Zeolites are ionic conductors and the cation electrical mobility in zeolites depends on their hydration state; consequently, the water adsorption/desorption process can be simply investigated by measuring the temporal evolution of current intensity in samples exposed to an environment with constant humidity or dry air, respectively. According to this kinetic analysis, a mechanism has been formulated for the water adsorption process able to justify the Lagergren pseudo-first-order kinetics observed for adsorption and the first-order kinetics observed for desorption. In this mechanism water molecules are first attract by the electric field of the cations and then they move at cation-framework interface to maximize the hydrogen bond interactions.
  • 1.1K
  • 28 Oct 2020
Topic Review
Diels–Alder Cycloaddition Reactions
Diels–Alder cycloaddition reaction is one of the most powerful strategies for the construction of six-membered carbocyclic and heterocyclic systems, in most cases with high regio- and stereoselectivity. An insight into the most relevant advances on sustainable Diels–Alder reactions since 2010 is provided. Various environmentally benign solvent systems are discussed, namely bio-based derived solvents, polyethylene glycol, deep eutectic solvents, supercritical carbon dioxide, water and water-based aqueous systems.
  • 1.1K
  • 25 Mar 2022
Topic Review
Sulfonamide
Sulfonamide is a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs. The original antibacterial sulfonamides are synthetic (nonantibiotic) antimicrobial agents that contain the sulfonamide group. Some sulfonamides are also devoid of antibacterial activity, e.g., the anticonvulsant sultiame. The sulfonylureas and thiazide diuretics are newer drug groups based upon the antibacterial sulfonamides. Allergies to sulfonamides are common. The overall incidence of adverse drug reactions to sulfa antibiotics is approximately 3%, close to penicillin; hence medications containing sulfonamides are prescribed carefully. Sulfonamide drugs were the first broadly effective antibacterials to be used systemically, and paved the way for the antibiotic revolution in medicine.
  • 1.1K
  • 23 Nov 2022
  • Page
  • of
  • 465
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Video Production Service
Feedback