Topic Review
Prevention of Alzheimer’s Disease in Daily Life
The ageing of the population is resulting in neurodegenerative diseases, including Alzheimer’s disease (AD), which are an increasing social, economic and medical problem. Diet and physical activity are now considered as important modifiable factors that help prevent or delay the development of AD and other dementia-related diseases. The pyramid of healthy nutrition and lifestyle is a way of presenting the principles, the implementation of which gives a chance for proper development and a long healthy life.
  • 23
  • 16 May 2022
Topic Review
Scientific Advances in Rheumatic Fever/Rheumatic Heart Disease Control
Despite the fact that rheumatic fever (RF) and rheumatic heart disease (RHD) have largely been eradicated from high-income countries, the disease spectrum remains endemic in many low- and middle-income countries (LMICs), extacting a grim health and socioeconomic impact. Over 33 million people are believed to be living with RHD worldwide, claiming nearly a third of a million lives annually. Regrettably, the neglect of RHD as a global health priority was further exacerbated by competing infectious disease outbreaks, chief among them the human immunodeficiency virus (HIV) epidemic. Nevertheless, the prior two decades have seen a slowly resurgence of interest in RF/RHD control. In this article, we present recent advances in the field of RF/RHD continuum control over this time period. Such primary advances include a better understanding the genetic predisposition to RHD, progress in Group A Streptococcus (GAS) vaccine development, and improved diagnostic strategies for GAS pharyngitis. Echocardiographic screening for RHD, in particular, has represented a major advance which has unearthed the prevailing high burden of RHD. Lastly, the recent demonstration of benefit of secondary antibiotic prophylaxis on halting progression of latent RHD has marked a major step forward in averting progression of end-stage valvular disease in LMIC settings. We provide a historical context within which these advances were realized, then close by summarizing major remaining gaps in research, illuminating potential future directions necessary to achieve global eradication of RHD.
  • 11
  • 16 May 2022
Topic Review
Competitive Golf and Energy Calculation
Nutritional guidance for competitive golfers to improve performance is limited.  A novel nutritional approach that incorporates carbohydrate supplementation to support aerobic fitness without sacrificing the ability to build strength is presented since longer courses require more stamina. Strategies for training, competition, and recovery are outlined based on different skill levels. American College of Sports Medicine (ACSM) guidelines for carbohydrates, protein, and hydration intake are tailored specifically for competitive golf based on this approach. Putting requires precise movement and can be affected by fatigue. Nutritional studies in golf and similar sports that require focused movements are presented, exhibiting an improvement with adequate hydration and carbohydrate status and caffeine use.
  • 19
  • 16 May 2022
Topic Review
Intergenerational Taekwondo Program
Taekwondo is a modernized martial art that includes various combinations of hand and kicking techniques and core values of Taekwondo philosophy such as courtesy, mutual respect, and self-control. Physical inactivity is highly prevalent among older adults and is a major contributor to health-related problems. Intergenerational physical activity programs are used as an effective tool to make a positive connection between generations and provide additional health benefits for both generations. 
  • 12
  • 16 May 2022
Topic Review
High-Intensity Functional Training in Elderly with Cognitive Impairment
High Intensity Functional Training (HIFT) is a new exercise modality that emphasizes multi-joint functional movements adaptable to any fitness level and promotes greater muscle recruitment.
  • 18
  • 16 May 2022
Topic Review
Myocardial Infarction and Immuno-Inflammatory Response in CAE
Coronary artery ectasia (CAE) is a relatively common coronary angiographic finding, with an incidence of 1.5–5% and geographical variations in prevalence. CAE has been associated with a male predominance. Anatomically, CAE more frequently affects the right coronary artery and the proximal one third of the vessels.
  • 22
  • 16 May 2022
Topic Review
A Systematic Approach to Healthcare Knowledge Management Systems
Big data in healthcare contain a huge amount of tacit knowledge that brings great value to healthcare activities such as diagnosis, decision support, and treatment. However, effectively exploring and exploiting knowledge on such big data sources exposes many challenges for both managers and technologists. A healthcare knowledge management system that ensures the systematic knowledge development process on various data in hospitals was proposed. It leverages big data technologies to capture, organize, transfer, and manage large volumes of medical knowledge, which cannot be handled with traditional data-processing technologies. In addition, machine-learning algorithms are used to derive knowledge at a higher level in supporting diagnosis and treatment.
  • 33
  • 13 May 2022
Topic Review
LACE Index Predicts High Risk of 30-Day Readmission
The LACE index accounts for: Length of stay (L), Acuity of admission (A), Comorbidities (C), and recent Emergency department use (E).  The incorporation of a high-risk LACE index showed favorable risk prediction and could be applied to predict 30-day readmission with chronic conditions. 
  • 95
  • 12 May 2022
Topic Review
Antioxidants for Patients with Fibromyalgia
Fibromyalgia (FM) is a syndrome characterized by chronic widespread pain. Pain is the predominant symptom; allodynia and hyperalgesia are also frequent. These patients also present severe fatigue, impaired cognition, and sleep disturbance, among others. In recent years, antioxidant supplements have become popular to counteract the effects of oxidative stress in fibromyalgia and one of its most distressing symptoms, pain. 
  • 22
  • 12 May 2022
Topic Review
Decrease Death Rate of Neonates
Neglected diseases still kill and disable too many, but no age group has in this regard received less attention than newborns. A newborn or neonate is a human from age 0 to 28 days. Worldwide, their contribution to death and disease is overwhelming and unequaled by any condition, while at the same time, its prevention and treatments are simple, relatively cheap, and efficient. 
  • 25
  • 12 May 2022
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