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Topic Review
Biography
Topic Review
Retinoic Acid and Retinaldehyde Dehydrogenase
Retinoic acid (RA) is an important biological metabolite synthesized from the retinol content (known as “vitamin A”) via a sequential cellular process in the retinoid signaling pathway (RSP). RSP-mediated RA biosynthesis is a vital physiological process in chordates, since RA interacts with the nuclear receptor superfamily, namely nuclear RA receptors (RARs) and retinoid X receptors (RXRs), bound to the RA response elements (RAREs) in the promoter region of RA target genes. Retinaldehyde dehydrogenases (RALDH) belongs to the oxidoreductase family and plays a critical role in RA synthesis from the retinaldehyde content; therefore, this enzyme is considered to be one of the key regulators of RA-related retinol metabolism and embryonic development.
594
27 Oct 2021
Topic Review
Natural Milk Microbiota
Profound bioactivities of raw breastmilk include benefits attributed to the dense and diverse natural microbiota, termed natural microbiota hereafter. Infants benefit from breastfeeding not just nutritionally, but by both ‘seeding and feeding’ the infant gut , providing microbes that seed the naïve gastrointestinal (GI or gut) ecosystem and nutritive components that feed both infant and microbial cells.
593
11 Nov 2021
Topic Review
Diffusion Weighted Imaging in Neuro-Oncology
Diffusion weighted imaging (DWI) is an imaging technique commonly used for the assessment of acute ischemia, inflammatory disorders, and CNS neoplasia. It has several benefits since it is a quick, easily replicable sequence that is widely used on many standard scanners. In addition to its normal clinical purpose, DWI offers crucial functional and physiological information regarding brain neoplasia and the surrounding milieu.
593
24 Apr 2023
Topic Review
Role of Blockchain Technology in COVID-19 Crisis
To obtain adequate performance in resolving issues that are associated with the COVID-19 pandemic, blockchain can be combined with other available technologies to establish a robust healthcare architecture.
593
29 Jan 2022
Topic Review
COVID-19 Impact on Yellow/Lassa Fever Infections in Nigeria
Lassa fever (LF) and yellow fever (YF) belong to a group of viral hemorrhagic fevers (VHFs). These viruses have common features and damages the organs and blood vessels; they also impair the body’s homeostasis. Some VHFs cause mild disease, while some cause severe disease and death such as in the case of Ebola or Marburg. LF virus and YF virus are two of the emerging viruses in Africa, resulting in severe hemorrhagic fever in humans. Lassa fever virus is continuously on the rise both in Nigeria and neighboring countries in West Africa, with an estimate of over 500,000 cases of LF, and 5000 deaths, annually. YF virus is endemic in temperate climate regions of Africa, Central America (Guatemala, Honduras, Nicaragua, El Salvador), and South America (such as Brazil, Argentina, Peru, and Chile) with an annual estimated cases of 200,000 and 30,000 deaths globally.
594
02 Dec 2022
Topic Review
COVID-19 Limitations on Doodling in Measuring Burnout
Burnout is a negative, job-related psychological state exhibited through physical fatigue, emotional exhaustion, and loss of motivation. Pre-COVID-19, doodling was identified as a measure of burnout in researchers attending a weekly, in-person health narratives research group manifesting team mindfulness. Doodling was not retained as a possible measure of burnout during COVID-19 once the weekly health narratives research group moved online and aware attention to present perceptions—one aspect of team mindfulness—was no longer evident.
592
17 Dec 2021
Topic Review
Treadmill Training Interventions on Elders with Neurological Disorders
Stroke, one of the most common neurological disorders, is a leading cause of long-term disability in older adults. Brain damage due to stroke can lead to symptoms such as cognitive and motor impairments including pain, paralysis, poor balance, spasticity, muscle weakness, and ineffective gait patterns.
591
25 Mar 2022
Topic Review
Caregiving in Parkinson´s Disease and Deep Brain Stimulation
In Parkinson’s disease (PD) patients, the progressive nature of the disease and the variability of disabling motor and non-motor symptoms contribute to the growing caregiver burden (CB) of PD partners and conflicts in their relationships. In advanced stages of the disease, Deep Brain Stimulation (DBS) improves PD symptoms and patients quality of life but the effect of DBS on CB of PD partners seems to be heterogeneous. The CB in the context of DBS framing both pre-, peri- and postoperative aspects aims to be illuminated, and further recognition of caregiver burden in partners of PD patients with DBS will be stimulated.
591
18 Feb 2022
Topic Review
Nature’s Role in Outdoor Therapies
Outdoor therapies are intentional therapeutic processes that are (1) place-based, (2) feature active bodily engagement, and (3) recognize nature-human kinship. Significant variety exists in practice, from walk and talk therapy, to expedition-based wilderness therapy, to garden and animal-assisted therapies. These approaches have shown improvement across a wide range of social, emotional, physical, physiological, and psychological outcomes and populations.
591
20 May 2021
Topic Review
Self-Care Research
Background: Theories can provide a foundation to explain behavior, investigate relationships, and to predict the effect of interventions. The aim of the study was to clarify the use of theories in studies testing interventions to promote self-care. Method: A scoping review. PubMed, EMBASE, PsychINFO, and CINAHL were searched from January 2008 through January 2019. Nine common chronic conditions were included. We included studies testing a self-care intervention if they used a randomized controlled trial design.
591
08 Jan 2021
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