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Topic Review
Innovative Strategies to Fuel Organic Food Business Growth
Whether consumers seek organic food for a healthy body or more as food for thought continues to be debated. Consumers do not need to be protected from the reality of organic food. The recommendation for marketers is to enhance the education of consumers and to pursue clear communication with them, as honesty may be the best policy here. Customers’ loyalty lies in trust, not in the brand. Availability, variety, and taste are the top three factors affecting consumers’ purchase decisions. Surprisingly, price or health consciousness is not the first concern for consumers.
  • 1.1K
  • 08 Mar 2022
Topic Review
Resveratrol in Autism Spectrum Disorders
Resveratrol (RSV) is a polyphenolic stillbenoid with significant anti-oxidative and anti-inflammatory properties recently tested in animal models of several neurological diseases. Altered immune alteration and oxidative stress have also been found in patients with autism spectrum disorders (ASD), and these alterations could add to the pathophysiology associated with ASD. 
  • 1.1K
  • 27 May 2021
Topic Review Peer Reviewed
Adverse Events Profile of COVID-19 Preventative Strategies
The COVID-19 pandemic has caused millions of deaths and has affected most people across the world, either directly or indirectly. Many preventative and therapeutic strategies have been employed since the beginning of the pandemic. With the development of the mRNA vaccine within a year of the start of the pandemic, we are entering a new era of vaccinology, and the adverse event profile of the COVID-19 vaccine is also becoming more apparent with time. While the benefits of the vaccines and other preventative strategies certainly outweigh the risk of adverse events, prospective clinical trials are urgently needed to determine whether specific populations, including those with a personal or family history of autoimmune disease, are at higher risk of developing certain adverse events, in order to minimize risk further.
  • 1.1K
  • 13 Apr 2022
Topic Review
2LARTH® Micro-Immunotherapy Treatment
Tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) are two cytokines involved in the perpetuation of the chronic inflammation state characterizing rheumatoid arthritis (RA). Significant advances in the treatment of this pathology have been made over the past ten years, partially through the development of anti-TNF and anti-IL-1 therapies. However, major side effects still persist and new alternative therapies should be considered.
  • 1.1K
  • 19 Nov 2021
Topic Review
Vitamin E and cardiovascular diseases
Cardiovascular diseases (CVD) cause about 1/3 of global deaths. Therefore, new strategies for the prevention and treatment of cardiovascular events are highly sought-after. Vitamin E is known for significant antioxidative and anti-inflammatory properties, and has been studied in the prevention of CVD, supported by findings that vitamin E deficiency is associated with increased risk of cardiovascular events. However, randomized controlled trials in humans reveal conflicting and ultimately disappointing results regarding the reduction of cardiovascular events with vitamin E supplementation. As we discuss in detail, this outcome is strongly affected by study design, cohort selection, co-morbidities, genetic variations, age, and gender. For effective chronic primary and secondary prevention by vitamin E, oxidative and inflammatory status might not have been sufficiently antagonized. In contrast, acute administration of vitamin E may be more translatable into positive clinical outcomes. In patients with myocardial infarction (MI), which is associated with severe oxidative and inflammatory reactions, decreased plasma levels of vitamin E have been found. The offsetting of this acute vitamin E deficiency via short-term treatment in MI has shown promising results, and, thus, acute medication, rather than chronic supplementation, with vitamin E might revitalize vitamin E therapy and even provide positive clinical outcomes.
  • 1.1K
  • 13 Oct 2020
Topic Review
Primary Health Care in Eswatini
Primary health care (PHC) is the first point of contact in a health system for most patients. It focuses on providing community-based health services that are equitable, comprehensive, affordable and accessible to all, throughout the life-course of an individual.
  • 1.1K
  • 14 Jul 2021
Topic Review
Music and Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a severe psychiatric disorder, which can be associated with music-related symptoms. Music may also be used as an adjunct treatment for OCD. Patients with OCD might benefit from music therapy, which includes listening to music.
  • 1.1K
  • 22 Nov 2021
Topic Review
Pedestrian Violations
Pedestrians are a vulnerable group of road users. Worldwide, the number of pedestrian deaths annually in road traffic accidents is about 270,000, which exceeds 22% of all traffic mortalities. This rate reveals its critical role in traffic safety research. Of these, pedestrian accidents mainly occur at signalized intersections when pedestrians illegally pass-through crosswalks, which are highly dangerous due to the high risk of pedestrian–vehicle interactions. Illegal crossings mainly include pedestrians crossing at red lights or outside of marked crosswalks, and the former usually causes severe harm. This risky behavior may raise traffic safety issues between pedestrians and driving vehicles. As such, it is necessary to analyze pedestrian red-light violations at signalized intersections and to reduce the risk of pedestrian crossing violations.
  • 1.1K
  • 14 Nov 2022
Topic Review
Psychomotor Agitation
The Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5) defines agitation as an excessive motor activity associated with a feeling of inner tension. Motor activity is usually non-productive and repetitious and can include behaviors such as pacing, fidgeting, hand wringing, pulling one’s clothes, and an inability to sit still. Even if aggression and violence are not core agitation features, a progression in agitation severity can lead to aggressive and violent behaviors. At the first International Experts’ Meeting on Agitation, agitation was defined as "a state where patients cannot remain still or calm, characterized by internal features such as hyperresponsiveness, racing thoughts, and emotional tension; and external ones, mainly motor and verbal hyperactivity, and communication impairment".
  • 1.1K
  • 13 May 2021
Topic Review
Non-Steroidal Anti-Inflammatory Drugs in the Fight against COVID-19
In Italy, a flowchart to be used by General Practitioners for the at-home treatment of patients with COVID-19, has been released. It states that early at-home treatment for SARS-CoV-2 infection is possible due to the availability of specific antiviral drugs to be used in at-risk patients, and that non-steroidal anti-inflammatory drugs (NSAIDs) have an important function in combating the virus. Therefore, the use of NSAIDs is not only rational but also effective in cases that cannot be treated using antivirals. 
  • 1.1K
  • 17 Mar 2023
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