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Topic Review
The Corona Dashboard in Context (‘Dutchboard’)
The core corona dashboard depicts quantitative data—systemically decomposed—on key facts of the space and time spread of COVID-19 cases. There are three context-specific factors that determine the trajectory of the spread of the corona virus: (i) the degree of vaccination intensity in a given country; (ii) the policy stringency in coping with the virus; (iii) the degree of intensity of social contacts. 
  • 424
  • 04 Mar 2022
Topic Review
Anorexia Nervosa, Body Representation and Virtual Reality Applications
Anorexia Nervosa (AN) patients exhibit distorted body representation related to perceptual and cognitive-emotional issues. Experimental paradigms are needed to manipulate the spatial content of these representations. Virtual Reality (VR) technology that implements full-body experiences may prove useful in clinical application.
  • 632
  • 04 Mar 2022
Topic Review
Circulating Tumor Cells in Metastatic Cascade
Circulating tumor cells (CTCs) are a heterogeneous population of tumor cells that have shed from a tumor into the lymphatics and vasculature, ultimately disseminating into blood circulation. Circulating tumor cells are a key player in cancer metastasis, a multi-step and complex process that involves (1) local invasion of primary tumor cells into adjacent tissue; (2) intravasation (trans-endothelial migration into nearby blood vessels); (3) circulation (transient travel and survival in the circulatory system as CTCs); (4) extravasation; (5) colonization. To successfully metastasize, CTCs must evade immune surveillance at every step once they leave the immunosuppressive tumor microenvironment. On the other hand, immune cells can promote or inhibit tumorigenesis, depending on the cell type and context.
  • 670
  • 04 Mar 2022
Topic Review
Bio-Signals in Medical Applications
Artificial Intelligence (AI) has broadly connected the medical field at various levels of diagnosis based on the congruous data generated. Different types of bio-signal can be used to monitor a patient’s condition and in decision making. Medical equipment uses signals to communicate information to care staff. AI algorithms and approaches will help to predict health problems and check the health status of organs, while AI prediction, classification, and regression algorithms are helping the medical industry to protect from health hazards. The early prediction and detection of health conditions will guide people to stay healthy.
  • 2.6K
  • 03 Mar 2022
Topic Review
Anthropometrics of Adolescent Swimmers Influence Stroking Parameters
Swimming is an individual and cyclic sport that is influenced by a multifactorial group of determinants, from which the biomechanical and energetical factors seem to be the most relevant. Swimming performance is determined by swimmers energetic profile, which is influenced by theirs biomechanical behaviour that, in turn, is affected by individuals anthropometric characteristics. This is known for adult and/or elite swimmers but it cannot be directly applied to younger counterparts since children and adolescents are not mini adults but individuals with specific characteristics and constraints. Anthropometric variables seem to be important for performance, particularly during growth, and there is a need for further study on this topic. 
  • 697
  • 03 Mar 2022
Topic Review
Malignant Mesothelioma
Malignant pleural mesothelioma (MPM) is a cancer mainly caused by asbestos fiber inhalation, characterized by an extremely long latency and poor prognosis.
  • 346
  • 03 Mar 2022
Topic Review
Cancer Diseases among Less-Developed Countries
Cancer is responsible for killing more people than HIV, malaria, and TB combined. Lower-income and lower-middle-income countries are mainly affected by these deadly diseases. 
  • 361
  • 02 Mar 2022
Topic Review
Lipsticks History, Formulations, and Production
Lipsticks are one of the most widely used cosmetic products. Social, psychological, and therapeutic benefits can be attained from using lipstick. The beauty and attractiveness of a person are enhanced as lipsticks colour the lips and protect them from the external environment.
  • 4.7K
  • 02 Mar 2022
Topic Review
Congenital Afibrinogenemia and Hypofibrinogenemia
Congenital fibrinogen disorders are rare pathologies of the hemostasis, comprising quantitative and qualitative disorders. The clinical phenotype is highly heterogeneous, being associated with bleeding, thrombosis, or absence of symptoms. Afibrinogenemia and hypofibrinogenemia are the consequence of mutations in the homozygous, heterozygous, or compound heterozygous state in one of three genes encoding the fibrinogen chains, which can affect the synthesis, assembly, intracellular processing, stability, or secretion of fibrinogen. In addition to standard coagulation tests depending on the formation of fibrin, diagnostics also includes global coagulation assays, which are effective in monitoring the management of replacement therapy. Genetic testing is a key point for confirming the clinical diagnosis. The identification of the precise genetic mutations of congenital fibrinogen disorders is of value to permit early testing of other at risk persons and better understand the correlation between clinical phenotype and genotype.
  • 553
  • 02 Mar 2022
Topic Review
Fibrinogen in Hypofibrinogenemia
Congenital fibrinogen disorders are diseases associated with a bleeding tendency; however, there are also reports of thrombotic events. Fibrinogen plays a role in the pathogenesis of thrombosis due to altered plasma concentrations or modifications to fibrinogen’s structural properties, which affect clot permeability, resistance to lysis, and its stiffness. Several distinct types of genetic change and pathogenetic mechanism have been described in patients with bleeding and a thrombotic phenotype, including mutations affecting synthesis or processing in three fibrinogen genes.
  • 558
  • 02 Mar 2022
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