Topic Review
Fruits Vinegar
Fruits vinegar (FsV) is a healthy drink wealthy in bioactive compounds that provide several beneficial properties. It contains a cocktail of bioactive ingredients including polyphenolic acids, organic acids, tetramethylperazine, and melanoidins. Acetic acid is the most abundant organic acid and chlorogenic acid is the major phenol in apple vinegar. The administration of fruits vinegar could prevent diabetes, hypercholesterolemia, oxidative stress, cancer, and boost immunity as well as provide a remarkable antioxidant ability. 
  • 583
  • 29 Mar 2022
Topic Review
Aeroterrestrial and Extremophilic Microalgae as Sources in Cosmetics
Microscopic prokaryotic and eukaryotic algae (microalgae), which can be effectively grown in mass cultures, are gaining increasing interest in cosmetics. Up to now, the main attention was on aquatic algae, while species from aeroterrestrial and extreme environments remained underestimated. In these habitats, algae accumulate high amounts of some chemical substances or develop specific compounds, which cause them to thrive in inimical conditions. Among such biologically active molecules is a large family of lipids, which are significant constituents in living organisms and valuable ingredients in cosmetic formulations. Therefore, natural sources of lipids are increasingly in demand in the modern cosmetic industry and its innovative technologies. Among novelties in skin care products is the use of lipid nanoparticles as carriers of dermatologically active ingredients, which enhance their penetration and release in the skin strata. 
  • 599
  • 29 Mar 2022
Topic Review
Therapeutic Aquatic Exercise in Pregnancy
Aquatic physical exercise aimed at pregnant women has proliferated in recent years, thanks to the benefits provided by the aquatic environment, such as a decrease in gravitational pull, an improved sense of physical comfort, improved mobility and flexibility, reduction of post-exercise pain and an improvement of venous return due to the increased hydrostatic pressure.
  • 405
  • 29 Mar 2022
Topic Review
Concussion Guidelines in Amateur Sports
It is widely recognised in sports medicine that sports-related concussion (SRC) is one of the most difficult injuries to detect, with more needed to be done to recognise, remove and treat athletes with the condition
  • 497
  • 29 Mar 2022
Topic Review
Microdosing in Business
Abusing psychoactive substances has been a popular sport in the business world since the mid-19th century. First, they were appreciated for their stimulating or tonic effects, but later with psychedelics on the scene, their importance in subculture matured. In the last decade, it has become very popular to use LSD and cocaine in subtle doses, which provides users with a high that is enough to feel their psychoactive potential, but not as high that significant behavioral changes can be seen. Unlike regular use, microdosing is usually sufficient to affect a few without undue finish and withdrawal symptoms. It allows for abuse in the regular mode of the working week with a rest phase on the weekend. The diametric difference between the abuse of standard dosing and micro-dosing is also in the decreasing tolerance of the organism.
  • 661
  • 29 Mar 2022
Topic Review
Resistance Training in Upper Extremity Muscles Improvement
High-intensity bench press training (g = 1.03) and 12 RM bench press exercises (g = 1.21) showed a large effect size on increasing pectoralis major muscle size. In the elbow extensors, large effects were reported for an increase in muscle size with isometric maximal voluntary co-contraction training (g = 1.97), lying triceps extension exercise (g = 1.25), and nonlinear periodised resistance training (g = 2.07). In addition, further large effects were achieved in the elbow flexors via traditional elbow flexion exercises (g = 0.93), concentric low-load forearm flexion-extension training (g = 0.94, g = 1), isometric maximal voluntary co-contraction training (g = 1.01), concentric low-load forearm flexion-extension training with blood flow restriction (g = 1.02, g = 1.07), and nonlinear periodised resistance training (g = 1.13, g = 1.34). Regarding the forearm muscles, isometric ulnar deviation training showed a large effect (g = 2.22) on increasing the flexor carpi ulnaris and radialis muscle size. Results show that these training modalities are suitable for gaining hypertrophy in the relevant muscles with at least four weeks of training duration.
  • 621
  • 29 Mar 2022
Topic Review
The Impact of Endocrine-Disrupting Chemicals in Male Fertility
Any compound or mixture of compounds, which interferes with any aspect of the endocrine system is classified as an endocrine-disrupting chemical (EDC). There is increasing evidence that male infertility is associated with the widespread exposure to EDCs, and in particular to obesogens. These compounds interfere with hormones involved in the regulation of metabolism and are associated with weight gain, being also able to change the functioning of the male reproductive axis and, consequently, the testicular physiology and metabolism that are pivotal for spermatogenesis. The disruption of these tightly regulated metabolic pathways leads to adverse reproductive outcomes. The permanent exposure to obesogens has raised serious health concerns. Evidence suggests that obesogens are one of the leading causes of the marked decline of male fertility and key players in shaping the future health outcomes not only for those who are directly exposed but also for upcoming generations. In addition to the changes that lead to inefficient functioning of the male gametes, obesogens induce alterations that are “imprinted” on the genes of the male gametes, establishing a link between generations and contributing to the transmission of defects.
  • 1.0K
  • 29 Mar 2022
Topic Review
Pathogenesis of Polycystic Ovary Syndrome
Polycystic ovary syndrome is a complex multisystem condition with metabolic, endocrine, psychological, fertility and pregnancy-related implications at all stages of life. The majority of women with PCOS manifest multiple metabolic features including obesity, insulin resistance (IR), hyperlipidemia and hyperandrogenism. PCOS results in an increased risk of developing metabolic disease (type 2 diabetes, non-alcoholic fatty liver disease and metabolic syndrome), cardiovascular disease, cancer, a wide array of pregnancy complications (deep venous thrombosis, pre-eclampsia, gestational diabetes, macrosomia, growth restriction, miscarriage, stillbirth and preterm labor) and psychological problems (anxiety, depression).
  • 488
  • 29 Mar 2022
Topic Review
Mycotoxin Exposure and Children’s Health
The first 1000 days of life are very sensitive to any event that alters health programming, and they represent a window for intervention to improve population health. Pregnant women, fetuses, and infants are particularly vulnerable to exposure to food contaminated with mycotoxins. 
  • 686
  • 29 Mar 2022
Topic Review
Therapeutic Options for Childhood Absence Epilepsy
Childhood absence epilepsy (CAE) is a common pediatric generalized epileptic syndrome. Although it is traditionally considered as a benign self-limited condition, the apparent benign nature of this syndrome has been revaluated in recent years. Old and new therapeutic options in particular for resistant forms of CAE are discussed in this entry. 
  • 399
  • 29 Mar 2022
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