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Topic Review
Chronic Inflammation in Cancer Cachexia
Cachexia, a type of metabolic syndrome linked to the disease, is associated with a dysregulation of metabolic pathways. Cancer Cachexia is a subtle condition that reduces patients’ quality of life by impairing their response to therapy and survival. Inflammatory mediators that may play a role in the pathogenesis of neoplastic cachexia, for example, overlap with those that may play a role in the pathogenesis of obesity. Cachexia is a complication of cancer-related malnutrition associated with catabolic/hypermetabolic changes.
  • 433
  • 05 May 2022
Topic Review
Fundamental/Longitudinal Life History Trade-Offs on Delay Discounting
Delay discounting (DD) was a product of two distinct life history trade-offs, reflecting both the trait-like quality and age-related development.  
  • 361
  • 05 May 2022
Topic Review
Neuropsychological Outcomes Associated with COVID-19
Survivors of COVID-19 often report subjective, cognitive complaints following infection, grossly characterized by cognitive inefficiency or “brain fog”. The nature of their objective, neuropsychological presentations are only beginning to be characterized. Risk factors predictive of neuropsychological outcomes post-infection remain under study. The contagiousness and quick rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, as well as the significant impact of COVID-19 disease on public health, make the study of COVID-19 on neuropsychological functioning particularly important. 
  • 483
  • 05 May 2022
Topic Review
Personalized Medicine and Health Care
Generally Big data is define as "data that contains greater variety, arriving in increasing volumes and with more velocity, also known as three Vs". Big data in health care is a fast-growing field and a new paradigm that is transforming case-based studies to large-scale and data-driven research. Big data is dependent on advancement of new data standards and modern technologies related to advanced research. Therefore, the future development of big data applications holds foreseeable promise in the modern day health care revolution. The immensely amount of large and rapidly growing of biomedical omics and clinical data create major challenges and opportunities for their analysis and interpretation and open new computational gateways to address these issues.
  • 475
  • 05 May 2022
Topic Review
Exercise Training on Depressive Symptoms in Cancer Patients
Cancer patients need to overcome several issues, leaving them more vulnerable to depressive symptoms. Exercise is recognised as a practice that helps to deal with depressive symptoms. This research includes  meta-analyses about the effect of exercise on depressive symptoms among cancer patients. Six studies were included. A significant reduction in depressive symptoms was observed because of exercise. However, the studies varied in methodological terms, making a broad generalisation difficult. It can be concluded that exercise is a good alternative to deal with depressive symptoms among cancer patients. Still, more studies are needed to clarify some aspects that are not answered yet. 
  • 479
  • 05 May 2022
Topic Review
Effects of Transcranial Electrical Stimulation in Numerical Cognition
It's showed that tRNS, thus far, seems to be the most promising transcranial electrical stimulation (tES) technique to enhance numerical cognition. Although the application of tES as a neuroenhancement or treatment approach in numerical cognition is promising, some questions remain. The optimal parameters and procedures of tES, the transfer effect to untrained numerical aspects, the sustained improvements in different aspects of numerical cognition, and the benefits of applying advanced tES techniques (i.e., HD-tDCS, tACS) have yet to be determined.
  • 406
  • 29 Apr 2022
Topic Review
Genotoxic Effects of Lead
Lead (Pb) is one of the most widely used heavy metals in several industries for the manufacturing process of Pb-based products due to its physical and chemical properties, such as high density, softness, malleability, and poor conductibility. Thus, Pb can be found in workplaces and other contaminated environments. Pb toxicity can occur via both nonoccupational and occupational exposure through inhalation, ingestion, and dermal absorption.
  • 495
  • 29 Apr 2022
Topic Review
Opportunistic Premise Plumbing Pathogens
Opportunistic premise plumbing pathogens (OPPP) are microorganisms that are native to the plumbing environment and that present an emerging infectious disease problem. They share characteristics, such as disinfectant resistance, thermal tolerance, and biofilm formation. The colonisation of domestic water systems presents an elevated health risk for immune-compromised individuals who receive healthcare at home.
  • 978
  • 29 Apr 2022
Topic Review
Depression and Perceived Social Support among Unemployed Youths
The issue of youth unemployment has begun to emerge in China. Unemployed young people are at high risk of depression and other mental health problems. Depression is an important health problem that can reduce individuals’ interest and pleasure in life and may trigger the risk of self-injury or suicide. In addition, depression can impair the ability to meet daily demands, the capacity to function well in society, and the competence to handle life challenges. For example, studies have reported that depressive symptoms of the unemployed decrease their job-search motivation, intensity, and quality of reemployment.
  • 604
  • 29 Apr 2022
Topic Review
Aptamer-Based Biosensors for Bisphenol A in Foodstuffs
Bisphenol A (BPA) is a synthetic compound utilized to manufacture plastics for Food Contact Materials (FCMs) or resins for the inside of food containers. Since it was recognized as an Endocrine-Disrupting Chemical (EDC), its implications in pathologies, such as cancer, obesity, diabetes, immune system alterations, and developmental and mental disorders, have been widely documented. Diet is considered the main source of exposure for humans to BPA. Consequently, continuous monitoring of the levels of BPA in foods is necessary to assess the risk associated with its consumption in one’s diet. 
  • 669
  • 29 Apr 2022
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