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Topic Review
Effects of COVID-19 on Rehabilitation Programs Outcomes
Consequences due to infection with SARS-CoV-2 virus can have a direct impact on skeletal muscle, due to the fact that both cardiac and skeletal muscle tissue show robust ACE2(angiotensin-converting enzyme 2) expression, suggesting a potential susceptibility to SARS-CoV-2 infection in both types of tissues. The musculoskeletal damage is firstly produced by the inflammatory effects, cytokine storm and muscle catabolism. However, myopathy, polyneuropathy and therapies such as corticoids were also considered important factors in muscle fatigue and functional incapacity. Pulmonary rehabilitation programs and early mobilization had a highly contribution during the acute phase and post-illness recovery process and helped patients to reduce dyspnea, increase the capacity of physical effort, overcome psychological disorders and improved the quality of their life. Muscular damage, as well as the decrease in the quality of life, are often a consequence of severe SARS-CoV-2 infection through: systemic inflammation, corticotherapy, prolonged bed rest and other unknown factors. Pulmonary rehabilitation programs and early mobilization had a highly contribution during the acute phase and post-illness recovery process and helped patients to reduce dyspnea, increase the capacity of physical effort, overcome psychological disorders and improve the quality of their life.
  • 468
  • 23 Sep 2022
Topic Review
Dietary Assessment Tools and Metabolic Syndrome
Metabolic syndrome (MS) is associated with a range of chronic diseases, for which lifestyle interventions are considered the cornerstone of treatment. Dietary interventions have primarily focused on weight reduction, usually via energy restricted diets. While this strategy can improve insulin sensitivity and other health markers, weight loss alone is not always effective in addressing all risk factors associated with MS.
  • 468
  • 13 Apr 2022
Topic Review
Four Strategies to Prevent Metabolic Syndrom
Metabolic syndrome (MetS) is a clustering of biochemical and physical conditions associated with an increased risk for developing type 2 diabetes (T2D) and cardiovascular diseases. Excess abdominal fat is most closely associated with metabolic risk factors and is most likely the initiating factor of risk factor clustering in MetS. These risk factors, namely, impaired blood glucose, dyslipidaemia, and raised blood pressure, are symptoms of metabolic chaos inside the body.
  • 467
  • 29 Mar 2022
Topic Review
Massive Open Online Courses in Healthcare Field
In the healthcare field, the need to ensure effective and economically sustainable training has led to a focus on technology-enhanced learning (TEL) and, specifically, to massive open online courses (MOOCs). These courses can be regarded as a significant step forward in the educational field due to the ease of access and convenient content delivery they offer. Specifically, MOOCs are courses potentially aimed at an unlimited number of students (massive). They can register free of charge (open) and enjoy, via the internet (online), learning-oriented content characterized by a structured learning plan (course).
  • 468
  • 14 Nov 2022
Topic Review
Role of 10-Hydroxy-2-decenoic Acid in Alzheimer’s Disease
Alzheimer’s disease (AD) represents a significant public health concern in modern society. Metabolic syndrome (MetS), which includes diabetes mellitus (DM) and obesity, represents a modifiable risk factor for AD. MetS and AD are interconnected through various mechanisms, such as mitochondrial dysfunction, oxidative stress, insulin resistance (IR), vascular impairment, inflammation, and endoplasmic reticulum (ER) stress. Therefore, it is necessary to seek a multi-targeted and safer approach to intervention. Thus, 10-hydroxy-2-decenoic acid (10-HDA), a unique hydroxy fatty acid in royal jelly, has shown promising anti-neuroinflammatory, blood–brain barrier (BBB)-preserving, and neurogenesis-promoting properties.
  • 471
  • 01 Sep 2023
Topic Review
COVID-19: Short and Long-Term Effects
The COVID-19 pandemic has recently been the cause of a global public health emergency. Frequently, elderly patients experience a marked loss of muscle mass and strength during hospitalization, resulting in a significant functional decline.
  • 467
  • 23 Jan 2021
Topic Review
Antimicrobial Use in COVID-19 Patients
There is an urgent need for further research and guidance in this field, from producing evidence-based guidelines, reassessing biomarkers for antimicrobial stewardship in COVID-19 patients, understanding drivers, benefits, and disbenefits of antibiotic use, and assessing the wider impact of the pandemic on antimicrobial use (AMU) and AMR. In this scoping review, we aim to: add to the research evidence on prevalence and patterns of antimicrobial use in the treatment of COVID-19 patients; identify the most commonly used antibiotics and clinical scenarios associated with AMU; and to explore any impact of AMU on patient treatment outcomes.
  • 467
  • 30 Jun 2021
Topic Review
Door-to-Door Transportation Services
A central issue in modern cities is providing inclusive transportation services for people with reduced mobility. In particular, Barcelona is offering a public door-to-door pickup transportation service complementary to the adapted regular public transport.
  • 467
  • 18 May 2022
Topic Review
Aspergillus Section Fumigati in Firefighter Headquarters
Aspergillus species are filamentous fungi commonly observed in different environmental compartments such as soil, water and air, with an emphasis on decaying vegetation, seeds and grains, where they prosper as saprophytes. Aspergillus species are also found in different indoor environments, and some species are considered opportunistic pathogens for humans. Aspergillus conidia can be abundant in outdoor and indoor environments and are easily dispersed in the air depending on the developed activities. Since the conidia are very small, they are easily inhaled and may colonize the upper and lower respiratory tract of exposed individuals. Aspergillus section Fumigati is one of the Aspergillus sections more frequently related to respiratory symptoms due to the small size of the conidia, thermotolerance, its nutritional versatility, and several other virulence factors . Additionally, the development of resistance to antifungal drugs, mainly in this Aspergillus section, is a phenomenon with growing prevalence in Europe, being associated with therapeutic failure and high mortality rates.
  • 466
  • 14 Oct 2021
Topic Review
Technologies to Assess COVID-19 Specific Antigens
In diagnosing SARS-CoV-2 infection, the most widely used test is the molecular testing. Real-time reverse transcription polymerase chain reaction (RT-PCR) is the most well-known and extensively used molecular analysis. The test relies on nucleic acid amplification and detects unique sequences of SARS-CoV-2. The other type of test, the antigen tests, can detect the presence of SARS-CoV-2 without amplifying viral components, but these tests are less sensitive than the molecular ones. Commonly, any negative antigen test is confirmed with a molecular test so that the patient can be declared negative for COVID-19. Both molecular and antigen tests would detect patients in the acute phase of infection.
  • 466
  • 21 Dec 2021
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