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All Topic Review Biography
Topic Review
Association between NAFLD and Infectious Diseases
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, affecting one third of the Western population. The hallmark of the disease is excessive storage of fat in the liver. Most commonly, it is caused by metabolic syndrome (or one of its components).
  • 428
  • 23 Dec 2022
Topic Review
Managing Oral Health in Context of Antimicrobial Resistance
The oral microbiome plays a major role in shaping oral health/disease state; thus, a main challenge for dental practitioners is to preserve or restore a balanced oral microbiome. Nonetheless, when pathogenic microorganisms install in the oral cavity and are incorporated into the oral biofilm, oral infections, such as gingivitis, dental caries, periodontitis, and peri-implantitis, can arise. Several prophylactic and treatment approaches are available nowadays, but most of them have been antibiotic-based. Given the actual context of antimicrobial resistance (AMR), antibiotic stewardship in dentistry would be a beneficial approach to optimize and avoid inappropriate or even unnecessary antibiotic use, representing a step towards precision medicine. 
  • 415
  • 23 Dec 2022
Topic Review
Knowledge Extraction for Health Management from Online Communities
Knowledge extraction from rich text in online health communities can supplement and improve the existing knowledge base, supporting evidence-based medicine and clinical decision making. The extracted time series health management data of users can help users with similar conditions when managing their health.
  • 412
  • 23 Dec 2022
Topic Review
Production and Use of Typical Rubber Antioxidants
Antioxidants are prevalently used during rubber production to improve rubber performance, delay aging, and extend service life. Studies have revealed that their transformation products (TPs) could adversely affect environmental organisms and even lead to environmental events, which led to great public concern about environmental occurrence and potential impacts of rubber antioxidants and their TPs.
  • 2.6K
  • 22 Dec 2022
Topic Review
Dietary Antioxidants and Lung Cancer in Smokers, Non-Smokers
Smoking is the major cause of cancer mortality, responsible for 64.2% of global lung cancer (LC)-related deaths in 2019. There is clear evidence from longitudinal and/or case–control studies that support the link between current smoking and LC risk. Secondhand smoke (SHS) as well as other environmental and genetic factors are potential risk factors for the development of LC in non-smokers. Approximately 6% of global non-smoker deaths from LC in 2019 are caused by SHS exposure.
  • 514
  • 21 Dec 2022
Topic Review
Neuropsychiatric Complications of SARS-CoV-2 Infection
Beginning with the various strategies of the SARS-CoV-2 virus to invade the bodies and manifest infection, and ending with the long COVID, people are witnessing the evolving course of the disease in addition to the pandemic. Given the partially controlled course of the COVID-19 pandemic, the greatest challenge lies in managing the short- and long-term complications of COVID-19.
  • 382
  • 20 Dec 2022
Topic Review
Viral Zoonotic Diseases and Male Reproduction
Zoonotic diseases occur as a result of human interactions with animals with the inadvertent transmission of pathogens from one to another. Zoonoses remain a major cause of morbidity and mortality among human populations, as they have been a source of pandemics in human history. Viral zoonoses account for a significant percentage of pathogens of zoonotic sources, posing a huge risk to men’s general health and fertility. Evidence from reviewed articles showed that viral zoonotic diseases elicit an immune reaction that induces inflammatory mediators and impairs testicular functions such as spermatogenesis and steroidogenesis, leading to abnormal semen parameters that lead to subfertility/infertility. Although most zoonotic viruses linger in semen long after recovery, their presence in semen does not directly translate to sexual transmission. 
  • 407
  • 20 Dec 2022
Topic Review
Environmental Stressors and the PINE Network
Both psychosocial and physical environmental stressors have been linked to chronic mental health and chronic medical conditions. The psycho-immune-neuroendocrine (PINE) network details metabolomic pathways which are responsive to varied stressors and link chronic medical conditions with mental disorders, such as major depressive disorder via a network of pathophysiological pathways. Biological links have been established between particulate matter (PM) exposure, key sub-networks of the PINE model and mental health sequelae, suggesting that in theory, long-term mental health impacts of PM exposure may exist, driven by the disruption of these biological networks. This disruption could trans-generationally influence health; however, long-term studies and information on chronic outcomes following acute exposure event are still lacking, limiting what is known beyond the acute exposure and all-cause mortality. More empirical evidence is needed, especially to link long-term mental health sequelae to PM exposure, arising from PINE pathophysiology. 
  • 377
  • 20 Dec 2022
Topic Review
Mechanisms for Reducing the Glycemic Response
Dietary fiber (DF), especially viscous DF, can contribute to a reduction in the glycemic response resulting from the consumption of carbohydrate-rich foods.
  • 506
  • 19 Dec 2022
Topic Review
Health Effects of Radiation Exposure
Computed tomography (CT) exposes patients to hazardous ionizing radiation, which carry the risk to damage the genetic material in the cells, leading to stochastic health effects in the form of heritable genetic mutations and increased cancer risk. These probabilistic, long-term carcinogenic effects of radiation can be seen over a lifetime and may sometimes take several decades to manifest. 
  • 644
  • 19 Dec 2022
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