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All Topic Review Biography
Topic Review
Urological Safety and COVID-19 Vaccinations
During the COVID-19 pandemic, elective surgeries were suspended for many months, and only high-risk oncological cases were addressed, although an ambulatory follow-up and management of benign conditions, which can cause lower urinary tract symptoms (LUTS), were essential. In neurologic patients, for example, LUTS have a great impact on quality of life and social life, and their clinical conditions can seriously worsen if not properly addressed.
  • 566
  • 24 Nov 2022
Topic Review
Mechanism of Actions of Long Non-Coding RNAs
Long non-coding RNAs (lncRNAs) are master regulators of almost all biological processes. LncRNAs perform their function mostly through different chromatin-based mechanisms such as signals, decoys, guides, and scaffolds in chromatin remodelling. LncRNAs play a major role in genomic imprinting. 
  • 565
  • 22 Nov 2022
Topic Review
Pro-Inflammatory Profile of Adipokines in Obesity
Obesity is a disease which leads to the development of many other disorders. Excessive accumulation of lipids in adipose tissue (AT) leads to metabolic changes, including hypertrophy of adipocytes, macrophage migration, changes in the composition of immune cells, and impaired secretion of adipokines. Adipokines are cytokines produced by AT and greatly influence human health.
  • 564
  • 20 Apr 2022
Topic Review
Electrochemical  Lactate (Bio)Sensor Transduction Approaches
Monitoring of lactate is spreading from the evident clinical environment, where its role as a biomarker is notorious, to the agrifood ambit as well. In the former, lactate concentration can serve as a useful indicator of several diseases (e.g., tumour development and lactic acidosis) and a relevant value in sports performance for athletes, among others. In the latter, the spotlight is placed on the food control, bringing to the table meaningful information such as decaying product detection and stress monitoring of species. No matter what purpose is involved, electrochemical (bio)sensors stand as a solid and suitable choice.
  • 564
  • 22 Nov 2022
Topic Review
Receptor-Mediated Targeted Delivery of Surface-ModifiedNanomedicine in Breast Cancer
Breast cancer therapeutic intervention continues to be ambiguous owing to the lack of strategies for targeted transport and receptor-mediated uptake of drugs by cancer cells. In addition to this, sporadic tumor microenvironment, prominent restrictions with conventional chemotherapy, and multidrug-resistant mechanisms of breast cancer cells possess a big challenge to even otherwise optimal and efficacious breast cancer treatment strategies. Surface-modified nanomedicines can expedite the cellular uptake and delivery of drug-loaded nanoparticulate constructs through binding with specific receptors overexpressed aberrantly on the tumor cell.
  • 563
  • 07 Feb 2022
Topic Review
Biosensors and Microfluidic Biosensors
Biosensors are ubiquitous in a variety of disciplines, such as biochemical, electrochemical, agricultural, and biomedical areas. They can integrate various point-of-care applications, such as in the food, healthcare, environmental monitoring, water quality, forensics, drug development, and biological domains. Multiple strategies have been employed to develop and fabricate miniaturized biosensors, including design, optimization, characterization, and testing. In view of their interactions with high-affinity biomolecules, they find application in the sensitive detection of analytes, even in small sample volumes. Among the many developed techniques, microfluidics have been widely explored; these use fluid mechanics to operate miniaturized biosensors. The currently used commercial devices are bulky, slow in operation, expensive, and require human intervention; thus, it is difficult to automate, integrate, and miniaturize the existing conventional devices for multi-faceted applications. Microfluidic biosensors have the advantages of mobility, operational transparency, controllability, and stability with a small reaction volume for sensing. 
  • 562
  • 05 Aug 2022
Topic Review
Arts Therapies for Eating Disorders
Eating disorders (EDs) are mental illnesses that cause serious disturbances to people’s everyday diet. Since EDs are on the rise throughout the world, healthcare policies and practitioners need to research different treatment options and their affectivity, value for patients, and cost effectiveness, in order to make any substantial change to the growth of this disease.
  • 562
  • 16 Apr 2021
Topic Review
Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Chemotherapy-induced peripheral neuropathy (CIPN) is widely recognized as a potentially severe toxicity that often leads to dose reduction or discontinuation of cancer treatment. Symptoms may persist despite discontinuation of chemotherapy and quality of life can be severely compromised. The clinical symptoms of CIPN, and the cellular and molecular targets involved in CIPN, are just as diverse as the wide variety of anticancer agents that cause peripheral neurotoxicity.
  • 561
  • 13 Jan 2022
Topic Review
Adequate Chronic Pain Care in Italy
Appropriate pain care should be regarded as a right and effectively guaranteed to people with chronic pain (CP). Additionally, the World Health Organization (WHO) has recognized the importance of addressing CP as a global public health concern and has recommended that pain management be integrated into primary healthcare systems. Many individuals with CP continue to experience barriers to accessing appropriate and effective pain care, including a lack of education and training among healthcare providers, limited availability of specialized pain clinics, and misconceptions about the use of opioid medications for pain management. Furthermore, CP patients often encounter social stigmatization and discrimination, which can further complicate their access to care. There is a need for ongoing efforts to improve the recognition, assessment, and management of chronic pain, and to ensure that individuals with CP have access to appropriate and effective pain care that addresses their physical, psychological, and social needs. Law 38, enacted in Italy in 2010, establishes the citizen’s right not to suffer.
  • 561
  • 12 Jan 2023
Topic Review
Women’s Empowerment, Food Security, Nutrition Transition in Africa
Despite mounting recognition of the essential role of women’s empowerment in household dietary and nutrition changes, the diversity of culture across African countries presents ambiguity as to whether its impact is experienced homogeneously across the continent. With their prominent role in the kitchen and household food preparation, women offer an important avenue for addressing several challenges in relation to the food subsector. Empowering them with the necessary capabilities can lead to changes in various aspects of households’ dietary patterns. Studies of Africa indicate that empowering women through physical capital, economic agency, and sociocultural factors can have a positive influence on either food security, diet improvements or the enrichment of diet-related health. 
  • 561
  • 09 Jan 2023
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