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Topic Review
Risk of Arsenic in Portuguese Rice
Arsenic is a metalloid with natural and anthropogenic sources and its inorganic form is toxic to humans. Rice is highly consumed worldwide and is prone to arsenic contamination.
  • 420
  • 25 Jan 2022
Topic Review
Plant-Derived Substances for Oral Health Care Products
Plant extracts are the current trend in the market, but it is also essential to consider their antibacterial, antioxidant, and sensory characteristics. Plant essential oils are constituted by secondary metabolites, such as terpenes, phenols, and aldehydes with antibacterial, antioxidant, and flavoring properties. Other industries take advantage of the essential oil properties; some examples of their applications are found in the food, pharmaceutical, and cosmetic industries.
  • 419
  • 29 Mar 2022
Topic Review
AI and Neural Network Algorithms
Al increases the potential of Micro-Electro-Mechanical System biosensors and opens up new opportunities for automation, consumer electronics, industrial manufacturing, defense, medical equipment, etc. Micro-Electro-Mechanical System microcantilever biosensors are currently making their way into the daily lives and playing a significant role in the advancement of social technology. Micro-Electro-Mechanical System biosensors with microcantilever structures have a num- ber of benefits over conventional biosensors, including small size, high sensitivity, mass production, simple arraying, integration, etc. These advantages have made them one of the development avenues for high-sensitivity sensors. The next generation of sensors will exhibit an intelligent development trajectory and aid people in interacting with other objects in a variety of scenario applications as a result of the active development of artificial intelligence (AI) and neural networks. A neural algorithm application in Micro-Electro-Mechanical System microcantilever biosensors is anticipated through the associated application of the principal com-ponent analysis approach. Researchers investigation has more scientific study value, because there are currently no favorable reports on the market regarding the use of AI with Micro-Electro-Mechanical System microcantilever sensors.
  • 419
  • 13 Sep 2022
Topic Review
Protective Textiles against Biological Threats
The development of protective clothing is crucial nowadays, as there are increased levels of harmful biological threats, both for military forces and civilians.
  • 418
  • 29 Apr 2022
Topic Review
Long COVID-19
“Long COVID-19” refers to the existence of symptoms weeks or months after contracting the SARS-CoV-2 infection, regardless of the viral state. The long COVID-19 or post COVID-19 condition is defined as the illness that arises in patients who have a history of suspected or confirmed SARS-CoV-2 infection, usually within three months of the commencement of COVID-19, with symptoms and consequences lasting at least two months.
  • 418
  • 19 Dec 2022
Topic Review
Post-COVID-19 Cardiopulmonary Rehabilitation
Managing cardiopulmonary rehabilitation in patients with COVID-19 remains a global challenge due to the facets of this virus. The technologies used in the rehabilitation of post-COVID-19 patients fail to keep pace with the global epidemiological developments.
  • 419
  • 21 Feb 2023
Topic Review
Therapeutic Response-Related Ferroptosis Regulators in Bladder Cancer
Ferroptosis, an iron-dependent form of regulated cell death characterized by the accumulation of lipid peroxidation, has been reported to regulate tumorigenesis, metastasis, drug resistance and the immune response. However, the potential roles of ferroptosis regulators in the progression of bladder cancer (BLCA) remain unknown. We systematically evaluated the multidimensional alteration landscape of ferroptosis regulators in BLCA and checked if their expression correlated with the ferroptosis index. Using least absolute shrinkage and selection operator (LASSO) regression and multivariate Cox regression, a seven ferroptosis regulator signature was constructed. We validated the prognostic and predictive accuracy of this signature in five independent datasets and established a nomogram to predict the overall survival (OS) and risk of death of BLCA patients. Moreover, the risk score was associated with tumor progression and antitumor immunity-related pathways. Furthermore, the relative antitumor immune cell infiltration level was negatively correlated with the risk score, and the tumor mutation burden was higher in the low-risk group, which might be useful for predicting immunotherapy efficacy. The Tumor Immune Dysfunction and Exclusion (TIDE) database and IMvigor210 cohort with immunotherapy efficacy results were used to confirm the prediction function of the risk score. Furthermore, the ferroptosis regulator signature could also reflect the chemotherapy sensitivity of BLCA. Ferroptosis might play a role in precision individualized chemotherapy and immunotherapy. This entry highlights the crucial clinical implications of ferroptosis and will help with developing personalized therapeutic strategies for BLCA patients
  • 418
  • 13 Dec 2021
Topic Review
The Pain at Work Toolkit
Self-management tools for people with chronic or persistent pain tend to focus on symptom reporting, treatment programmes or exercise and do not address barriers to work, facilitators of work ability, or workplace pain self-management strategies. Researchers developed the Pain at Work (PAW) toolkit, an evidence-based digital toolkit to provide advice on how employees can self-manage their pain at work. In a collaborative-participatory design, 4-step Agile methodology (N = 452) was used to co-create the toolkit with healthcare professionals, employers and people with chronic or persistent pain. Step 1: stakeholder consultation event (n = 27) established content and format; Step 2: online survey with employees who have persistent pain (n = 274) showed employees fear disclosing their condition, and commonly report discrimination and lack of line manager support. Step 3: online employer survey (n = 107) showed employers rarely provide self-management materials or education around managing pain at work, occupational health recommendations for reasonable adjustments are not always actioned, and pain-related stigma is common. Step 4: Toolkit development integrated findings and recommendations from Steps 1–3, and iterative expert peer review was conducted (n = 40). The PAW toolkit provides (a) evidence-based guidelines and signposting around work-capacity advice and support; (b) self-management strategies around working with chronic or persistent pain, (c) promotion of healthy lifestyles, and quality of life at work; (d) advice on adjustments to working environments and workplace solutions to facilitate work participation.
  • 418
  • 14 Jan 2022
Topic Review
Intergenerational Taekwondo Program
Taekwondo is a modernized martial art that includes various combinations of hand and kicking techniques and core values of Taekwondo philosophy such as courtesy, mutual respect, and self-control. Physical inactivity is highly prevalent among older adults and is a major contributor to health-related problems. Intergenerational physical activity programs are used as an effective tool to make a positive connection between generations and provide additional health benefits for both generations. 
  • 418
  • 16 May 2022
Topic Review
Subgroups Identification of Chronic Low Back Pain Patients
The identification of homogeneous subgroups of patients with chronic low back pain (CLBP), based on distinct patterns of motor control, could support the tailoring of therapy and improve the effectiveness of rehabilitation. Differences in the patterns of motor control can be identified using outcome measures based on muscle activation or kinematic movement patterns, representing the outcomes of neural structures and processes.
  • 417
  • 08 Jan 2022
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