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Topic Review
Problems Associated with Moulds in Foodstuffs
Two downsides associated with the mould contamination of food are of interest: spoilage and mycotoxin production provoking food quality and food safety concerns, respectively.
  • 436
  • 13 Mar 2023
Topic Review
Probiotics, Prebiotics, and Phytogenic Substances for Gut Health
The gut microbiota has been designated as a hidden metabolic ‘organ’ because of its enormous impact on host metabolism, physiology, nutrition, and immune function. The connection between the intestinal microbiota and their respective host animals is dynamic and, in general, mutually beneficial. This complicated interaction is seen as a determinant of health and disease; thus, intestinal dysbiosis is linked with several metabolic diseases. Therefore, tractable strategies targeting the regulation of intestinal microbiota can control several diseases that are closely related to inflammatory and metabolic disorders. As a result, animal health and performance are improved. One of these strategies is related to dietary supplementation with prebiotics, probiotics, and phytogenic substances. These supplements exert their effects indirectly through manipulation of gut microbiota quality and improvement in intestinal epithelial barrier. 
  • 810
  • 16 Feb 2022
Topic Review
Probiotics and Synbiotics on Hirsutism
Probiotics and synbiotics are known to have beneficial effects on human health and disease. Hirsutism, a disorder that is characterised by the presence of coarse terminal hairs in a male-like pattern, is usually caused by elevated androgen levels in blood plasma. This disorder is usually ob-served in PCOS women and it is linked to insulin resistance (IR). Although idiopathic hirsutism (IH) is not shown to have excess androgen production from the ovarian and adrenal glands, in-creased 5α-reductase in peripheral tissues and insulin resistance are common observations.
  • 967
  • 27 Jan 2021
Topic Review
Probiotics and Probiotic-like Agents against Chemotherapy-Induced Intestinal Mucositis
Cancer chemotherapy has allowed many patients to survive, but not without risks derived from its adverse effects. Drugs, such as 5-fluorouracil, irinotecan, oxaliplatin, methotrexate, and others, as well as different drug combinations trigger intestinal mucositis that may cause or contribute to anorexia, pain, diarrhea, weight loss, systemic infections, and even death. Dysbiosis is a hallmark of chemotherapy-induced intestinal mucositis and diarrhea, and, therefore, strategies aimed at modulating intestinal microbiota may be useful to counteract and prevent those dreadful effects.
  • 426
  • 25 Oct 2023
Topic Review
Probiotics and Prebiotics Concepts
Probiotics are microorganisms which, if taken in sufficient quantities, contribute positively to the health of the host and are the focus of both scientific studies and commercial companies. 
  • 415
  • 06 Apr 2023
Topic Review
Pro-Inflammatory Profile of Adipokines in Obesity
Obesity is a disease which leads to the development of many other disorders. Excessive accumulation of lipids in adipose tissue (AT) leads to metabolic changes, including hypertrophy of adipocytes, macrophage migration, changes in the composition of immune cells, and impaired secretion of adipokines. Adipokines are cytokines produced by AT and greatly influence human health.
  • 552
  • 20 Apr 2022
Topic Review
Prioritizing the Patient’s Needs of Missed Nursing Care
Missed nursing care refers to essential nursing activities or tasks that are omitted or not completed as planned during a patient’s care. This omission can result from various factors, such as staffing shortages, time constraints, or communication issues, and it can potentially compromise the quality of patient care and safety. Identifying and addressing missed nursing care is crucial to ensure optimal patient outcomes and the well-being of healthcare professionals. 
  • 142
  • 25 Jan 2024
Topic Review
Primary, Secondary and Tertiary Prevention of Pediatric OCD
Obsessive-compulsive disorder (OCD) is a psychiatric disorder characterized by intrusive, repeated and persistent thoughts, desires or images, with subsequent repetitive behaviors or thinking patterns that the individual performs in an attempt to decrease the anxiety or distress or simply according to rigid rules (i.e. compulsions).As a distinctive subtype of OCD, pediatric-onset OCD affects around 2% to 4% of children and adolescents. Considering that children and adolescents are in a critical stage of physical and cognitive development, the onset of OCD during this period may lead to additional developmental disruptions.There is an urgent need for early diagnosis and treatment for OCD, especially the strategies targeting the childhood age group. 
  • 385
  • 11 Apr 2023
Topic Review
Primary Healthcare
Total health expenditure in China has grown considerably since a new round of health system reform was enacted in 2009. Researchers have shown that strengthening primary healthcare may be an option for countries to solve the rapid expansion of their medical expenditures. This study was designed to explore the association between the strength of primary healthcare and medical expenditures, in the context of the hospital-oriented healthcare system in China. A longitudinal ecological study was conducted using a 5-year panel dataset of 27 provinces in mainland China. The linear mixed effects regression model was used to assess the effects of primary healthcare-related metrics on medical expenditures, controlling for the provincial level specialty care physician supply and socio-economic parameters. All of the three primary healthcare-related metrics showed negative associations with the two medical expenditure parameters. Primary care physicians per 10,000 population was significantly associated with the per capita hospital medical expenditures (p < 0.05), and the percentage of public health expenditure in total health expenditure was significantly associated with both per capita total medical expenditure and per capita hospital medical expenditures (p < 0.01 for both). Our study found negative associations between the primary healthcare capacity and medical expenditure in the context of hospital-oriented healthcare systems in China, adding to the previous evidence that primary healthcare may play a positive role in reducing medical expenditure. Policies on increasing the primary care physician supply and the public share of total health expenditure should be conducted to strengthen the primary healthcare system. With the gradual advance of medical reform and the policy inclination to primary healthcare, this will play a more important role in controlling the rapid growth of medical expenditure.
  • 620
  • 19 Jan 2021
Topic Review
Primary Health Care in Eswatini
Primary health care (PHC) is the first point of contact in a health system for most patients. It focuses on providing community-based health services that are equitable, comprehensive, affordable and accessible to all, throughout the life-course of an individual.
  • 1.1K
  • 14 Jul 2021
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