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Topic Review
Propolis in Periodontal Disease
Propolis is a natural substance produced by bees which has proven useful for treating periodontal disease. 
  • 689
  • 25 Feb 2021
Topic Review
Microbiological Food Safety of Seaweeds
The use of seaweeds in the human diet has a long history in Asia and has now been increasing also in the western world. Concurrent with this trend, there is a corresponding increase in cultivation and harvesting for commercial production. Edible seaweed is a heterogenous product category including species within the green, red, and brown macroalgae. Moreover, the species are utilized on their own or in combinatorial food products, eaten fresh or processed by a variety of technologies. 
  • 688
  • 11 Nov 2021
Topic Review
Pharmaceutical Service
Pharmaceutical services are activities of pharmacists in the healthcare system to obtain a measurable benefit, including providing access to high-quality medicinal products, subsequent rational management, as well as preventive medicine.
  • 689
  • 12 Nov 2020
Topic Review
Hybrid Nanobioengineered Nanomaterial-Based Electrochemical Biosensors
Nanobioengineered-based hybrid electrochemical biosensors exploit the synergistic properties of hybrid systems that connect biomolecules with nanomaterials to engineer highly sensitive biosensing platforms for the specific electrochemical detection of different target analytes.
  • 687
  • 30 Jun 2022
Topic Review
Bone Health in Prostate Cancer Disease
Prostate cancer (PCa) is the second-leading cause of cancer-related deaths in men. PCa cells require androgen receptor (AR) signaling for their growth and survival. Androgen deprivation therapy (ADT) is the preferred treatment for patients with locally advanced and metastatic PCa disease. Bone-metastasis-induced early changes in the bone that proceed the osteoblastic response in the bone matrix are monitored and detected via modern magnetic resonance and PET/CT imaging technologies.
  • 687
  • 14 Sep 2022
Topic Review
Unobtrusive Monitoring of Sleep Cycles
Polysomnography is the gold-standard method for measuring sleep but is inconvenient and limited to a laboratory or a hospital setting. As a result, the vast majority of patients do not receive a proper diagnosis. In an attempt to solve this issue, sleep experts are continually looking for unobtrusive and affordable alternatives that can provide longitudinal sleep tracking. Collecting longitudinal data on sleep can accelerate epidemiological studies exploring the effect of sleep on health and disease. These alternatives can be in the form of wearables (e.g., actigraphs) or nonwearable (e.g., under-mattress sleep trackers). 
  • 685
  • 19 Apr 2022
Topic Review
Genetically Modified Food
The concept of “genetically modified organisms” (GMOs) refers to those organisms whose genome has been altered by inserting a gene from another organism, removing a gene, or changing a gene’s function to generate a desirable trait.
  • 684
  • 25 Mar 2022
Topic Review
Anti-Depressant Properties of Crocin Molecules in Saffron
Saffron is a valued herb, obtained from the stigmas of the C. sativus Linn (Iridaceae), with therapeutic effects. It has been described in pharmacopoeias to be variously acting, including as an anti-depressant, anti-carcinogen, and stimulant agent. The therapeutic effects of saffron are harbored in its bioactive molecules, notably crocins, the subject of this research. Crocins have been demonstrated to act as a monoamine oxidase type A and B inhibitor. Furthermore, saffron petal extracts have experimentally been shown to impact contractile response in electrical field stimulation. Other research suggests that saffron also inhibits the reuptake of monoamines, exhibits N-methyl-d-aspartate antagonism, and improves brain-derived neurotrophic factor signaling. A host of experimental studies found saffron/crocin to be similarly effective as fluoxetine and imipramine in the treatment of depression disorders. Saffron and crocins propose a natural solution to combat depressive disorders. However, some hurdles, such as stability and delivery, need to be overcome.
  • 685
  • 01 Apr 2022
Topic Review
Skeletal Fluorosis
Fluorine is widely dispersed in nature and has multiple physiological functions. Although it is usually regarded as an essential trace element for humans, this view is not held universally. Moreover, chronic fluorosis, mainly characterized by skeletal fluorosis, can be induced by long-term excessive fluoride consumption. High concentrations of fluoride in the environment and drinking water are major causes, and patients with skeletal fluorosis mainly present with symptoms of osteosclerosis, osteochondrosis, osteoporosis, and degenerative changes in joint cartilage. Etiologies for skeletal fluorosis have been established, but the specific pathogenesis is inconclusive. Currently, active osteogenesis and accelerated bone turnover are considered critical processes in the progression of skeletal fluorosis. In recent years, researchers have conducted extensive studies in fields of signaling pathways (Wnt/β-catenin, Notch, PI3K/Akt/mTOR, Hedgehog, parathyroid hone, and insulin signaling pathways), stress pathways (oxidative stress and endoplasmic reticulum stress pathways), epigenetics (DNA methylation and non-coding RNAs), and their inter-regulation involved in the pathogenesis of skeletal fluorosis.
  • 684
  • 11 Nov 2021
Topic Review
Telehealth and Artificial Intelligence during the COVID-19 Pandemic
Telemedicine enables clinical services to use information technology, video imaging, and telecommunication links to deliver healthcare services at a distance. In contrast to telemedicine, which is defined as the provision of medical services at a distance by a physician, telehealth is an umbrella word that encompasses telemedicine as well as a number of nonphysician services such as telenursing and telepharmacy. Telemedicine is often used for controlling chronic diseases such as cardiovascular diseases, diabetes mellitus, cancer, and mental disorders.
  • 684
  • 07 Mar 2022
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