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Topic Review
Pathogenesis of Polycystic Ovary Syndrome
Polycystic ovary syndrome is a complex multisystem condition with metabolic, endocrine, psychological, fertility and pregnancy-related implications at all stages of life. The majority of women with PCOS manifest multiple metabolic features including obesity, insulin resistance (IR), hyperlipidemia and hyperandrogenism. PCOS results in an increased risk of developing metabolic disease (type 2 diabetes, non-alcoholic fatty liver disease and metabolic syndrome), cardiovascular disease, cancer, a wide array of pregnancy complications (deep venous thrombosis, pre-eclampsia, gestational diabetes, macrosomia, growth restriction, miscarriage, stillbirth and preterm labor) and psychological problems (anxiety, depression).
  • 488
  • 29 Mar 2022
Topic Review
Mycotoxin Exposure and Children’s Health
The first 1000 days of life are very sensitive to any event that alters health programming, and they represent a window for intervention to improve population health. Pregnant women, fetuses, and infants are particularly vulnerable to exposure to food contaminated with mycotoxins. 
  • 686
  • 29 Mar 2022
Topic Review
Therapeutic Options for Childhood Absence Epilepsy
Childhood absence epilepsy (CAE) is a common pediatric generalized epileptic syndrome. Although it is traditionally considered as a benign self-limited condition, the apparent benign nature of this syndrome has been revaluated in recent years. Old and new therapeutic options in particular for resistant forms of CAE are discussed in this entry. 
  • 400
  • 29 Mar 2022
Topic Review
Dairy Lactic Acid Bacteria in Dietetics
Fermented dairy products are the good source of different species of live lactic acid bacteria (LAB), which are beneficial microbes well characterized for their health-promoting potential. Traditionally, dietary intake of fermented dairy foods has been related to different health-promoting benefits including antimicrobial activity and modulation of the immune system, among others. In recent years, emerging evidence suggests a contribution of dairy LAB in the prophylaxis and therapy of non-communicable diseases. Live bacterial cells or their metabolites can directly impact physiological responses and/or act as signalling molecules mediating more complex communications. This entry provides up-to-date knowledge on the interactions between LAB isolated from dairy products (dairy LAB) and human health by discussing the concept of the food–gut-health axis. In particular, some bioactivities and probiotic potentials of dairy LAB have been provided on their involvement in the gut–brain axis and non-communicable diseases mainly focusing on their potential in the treatment of obesity, cardiovascular diseases, diabetes mellitus, inflammatory bowel diseases, and cancer.
  • 652
  • 29 Mar 2022
Topic Review
Family Context, Parenting and Child Development
Based on the identification of a key developmental process in which interactions are continuously internalised, using an epigenetic approach draws attention to the bidirectional and systemic nature of intrafamily and parenting interactions and highlights the multiple factors that influence them, which are linked to the developmental history of the species, the individual characteristics of both the child and their parents, and contextual variables. In response to these internalised interactions, the body activates epigenetic mechanisms, such as DNA methylation, which without changing the structure of genes, may affect the expression of the genome leading to a variety of diseases and phenotypic profiles.
  • 593
  • 29 Mar 2022
Topic Review
Molecular Techniques for Schistosomiasis
Diagnostic tools play a pivotal role in warfare against schistosomiasis but must adapt to the endemic status and objectives of activities. With the decrease of prevalence and infection intensity of schistosomiasis in human beings and livestock, optimal methodologies with high sensitivity and absolute specificity are needed for the detection of asymptomatic cases or light infections, as well as disease surveillance to verify elimination. In comparison with the parasitological methods with relatively low sensitivity and serological techniques lacking specificity, which both had been widely used in previous control stages, the molecular detection methods based on the amplification of promising genes of the schistosome genome may pick up the baton to assist the eventual aim of elimination.
  • 528
  • 29 Mar 2022
Topic Review
Plant-Derived Substances for Oral Health Care Products
Plant extracts are the current trend in the market, but it is also essential to consider their antibacterial, antioxidant, and sensory characteristics. Plant essential oils are constituted by secondary metabolites, such as terpenes, phenols, and aldehydes with antibacterial, antioxidant, and flavoring properties. Other industries take advantage of the essential oil properties; some examples of their applications are found in the food, pharmaceutical, and cosmetic industries.
  • 420
  • 29 Mar 2022
Topic Review
Pharmacologic and Clinical Considerations of Nalmefene
Nalmefene is a pure opioid antagonist structurally similar to naltrexone that can serve as an alternative antidote for reversing respiratory depression associated with acute opioid overdose. Nalmefene is also known as 6-methylene naltrexone. Its main features of interest are its prolonged duration of action that surpasses most opioids and its ability to serve as an antidote for acute opioid overdose.
  • 1.6K
  • 29 Mar 2022
Topic Review
Essential Oils from Lamiaceae Family
Essential oils from different plant species were found to contain different compounds exhibiting anti-inflammatory effects with the potential to be a valid alternative to conventional chemotherapy that is limited in long-term use due to its serious side effects.
  • 631
  • 29 Mar 2022
Topic Review
Nutritional Status of Landfill Waste Pickers
Waste pickers are an extremely vulnerable population from an occupational health perspective. In addition, their precarious income generation and fierce relative competition for “spots” on landfill sites to seek out a livelihood compromise their health seeking behaviour, yet they contribute to reduction of waste to landfill sites and environmental sustainability. Knowledge and understanding of the lived realities of waste pickers should guide service delivery planning by community nutrition and public health practitioners. 
  • 487
  • 28 Mar 2022
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