Topic Review
Crisis-focused Psychological Interventions
Public safety personnel (PSP) and frontline healthcare professionals (FHP) are frequently exposed to potentially psychologically traumatic events (PPTEs), and report increased rates of post-traumatic stress injuries (PTSIs). Despite widespread implementation and repeated calls for research, effectiveness evidence for organizational post-exposure PTSI mitigation services remains lacking.
  • 722
  • 10 Dec 2020
Topic Review
Death Anxiety
Death anxiety is an unavoidable common phenomenon in our lives across cultures and religions. It is multidimensional and explained by different theoretical frameworks. Death anxiety can have negative impacts on wellbeing. Death is an inevitable experience that generates a reduced sense of safety and stronger fear (Alkozei et al. 2019). 
  • 6.4K
  • 06 Feb 2021
Topic Review
Delirium
Delirium is a set of neuropsychiatric symptoms, including qualitative disturbances of consciousness and attention, which may be accompanied by cognitive deficits and psychotic symptoms. The incidence of delirium varies from several percent in patients hospitalized in general wards up to 80% in patients with multi-organ failure treated in intensive care units. Delirium worsens the prognosis, extends hospitalization time, and may increase mortality.
  • 997
  • 27 Aug 2020
Topic Review
Delusional Disorder
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) defines delusional disorder (DD) as the presence of one or more delusions, lasting for at least one month or longer, in the absence of affective symptoms, prominent hallucinations or other symptoms of schizophrenia. The prevalence of DD is estimated to be approximately 0.2%. Subtypes of DD have been categorized according to the content of the primary delusion: persecutory, jealous, erotomanic, somatic, grandiose, mixed and unspecified.
  • 533
  • 08 Dec 2020
Topic Review
Depressive and Alcohol Use Disorders
Depressive disorders and alcohol use disorders are widespread among the general population and are significant public health and economic burdens. Alcohol use disorders often co-occur with other psychiatric conditions and this dual diagnosis is called comorbidity. Depressive disorders invariably contribute to the development and worsening of alcohol use disorders, and vice versa. The mechanisms underlying these disorders and their comorbidities remain unclear. Recently, interest in the lateral habenula, a small epithalamic brain structure, has increased because it becomes hyperactive in depression and alcohol use disorders, and can inhibit dopamine and serotonin neurons in the midbrain reward center, the hypofunction of which is believed to be a critical contributor to the etiology of depressive disorders and alcohol use disorders as well as their comorbidities. Additionally, calcium/calmodulin-dependent protein kinase II (CaMKII) in the lateral habenula has emerged as a critical player in the etiology of these comorbidities.
  • 422
  • 03 Dec 2020
Topic Review
Effects of Stress Exposure
Stress could be defined as an organism's entire response to environmental demands or strains. Exposure to highly stressful or traumatic events, depending on the stage of life in which stress exposure occurs, could severely affect limbic structures, including the amygdala, and lead to alterations in social and affective behaviors.
  • 1.6K
  • 30 Jan 2021
Topic Review
Epigenomic Dysregulation in Schizophrenia
       Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms that causes very significant disability in young people. While schizophrenia has a strong genetic component, with heritability around 80%, there is also a very significant range of environmental exposures and stressors that have been implicated in disease development and neuropathology, such as maternal immune infection, obstetric complications, childhood trauma and cannabis exposure. It is postulated that epigenetic factors, as well as regulatory non-coding RNAs, mediate the effects of these environmental stressors. In this review, we explore the most well-known epigenetic marks, including DNA methylation and histone modification, along with emerging RNA mediators of epigenomic state, including miRNAs and lncRNAs, and discuss their collective potential for involvement in the pathophysiology of schizophrenia implicated through the postmortem analysis of brain tissue. Given that peripheral tissues, such as blood, saliva, and olfactory epithelium have the same genetic composition and are exposed to many of the same environmental exposures, we also examine some studies supporting the application of peripheral tissues for epigenomic biomarker discovery in schizophrenia. Finally, we provide some perspective on how these biomarkers may be utilised to capture a signature of past events that informs future treatment.
  • 659
  • 27 Aug 2020
Topic Review
European Policy Preventing Internet Addiction
Internet use-related addiction problems are increasingly being recognized on a European scale due to international health organizations considering gaming addiction. In April 2013, the American Psychiatric Association recognized Internet Gaming Disorder in the fifth Diagnostic and Statistical Manual of Mental Disorders, and in April 2018, the World Health Organization included Gaming Disorder in the eleventh International Classification of Diseases. However, findings on these problems within this period are lacking in Europe, and a preventive approach is missing globally. A detailed critical literature review was conducted using PsycINFO and Web of Science in this five-year period. A total of 19 studies were reviewed and problems identified were: generalized Internet addiction and online gaming and gambling addictions across seven European countries (i.e., Spain, Germany, France, Italy, Greece, The Netherlands, and Denmark). The individuals with problematic use were found to be educated adolescents, usually young males with comorbid disorders, and gaming and gambling disorders were implicated in the most severe cases. Cognitive behavioral therapy was the main treatment, sometimes combined with a systemic approach for adolescents. Prevalence, high-risk populations, and factors contributing to these addiction problems are discussed, and a set of policy options are developed for this region. The implications for early detection, diagnosis, treatment, and prevention in Europe are considered.
  • 1.6K
  • 06 Nov 2020
Topic Review
FNIRS application in Parkinson’s Disease
The management of people affected by neurological disorders, such as Parkinson's disease, requires the adoption of targeted and cost-effective interventions to cope with chronicity. Although therapy adaptation and rehabilitation represent major targets, affordable and reliable neurophysiological correlates of cerebral activity to be used throughout treatment stages are often lacking. The functional Near-Infrared Spectroscopy (fNIRS) represents a versatile optical neuroimaging technology for investigating cortical hemodynamic activity in the most common chronic neurological conditions, including Parkinson's disease, with the advantages of non-invasiveness and portability which make fNIRS suitable for carrying out multiple measurements in rehabilitation settings.
  • 994
  • 21 Oct 2020
Topic Review
Fruit and Vegetable Intake and Mental Health in Adults
High total intake of fruits and vegetables, and some of their specific subgroups including berries, citrus, and green leafy vegetables, may promote higher levels of optimism and self-efficacy, as well as reduce the level of psychological distress, ambiguity, and cancer fatalism, and protect against depressive symptoms. The general recommendation to consume at least 5 portions of fruit and vegetables a day may be beneficial also for mental health.
  • 1.0K
  • 30 Oct 2020
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