Topic Review
Audiovestibular Disorders after COVID-19 Vaccine
The SARS-CoV-2 vaccination campaign is probably one of the most historic public hygiene measures in modern medicine. The drama of the pandemic has forced the scientific community to accelerate the development and commercialization of vaccines, thereby enhancing the phases of active surveillance. Among the adverse events following immunization (AEFI) reported, those of an audiovestibular interest, such as sudden sensorineural hearing loss (SSNHL), tinnitus, dizziness, and vertigo, constitute a very small percentage.
  • 170
  • 05 May 2022
Topic Review
Extracellular Vesicles in Head and Neck Surgery
EVs has spread from various medical fields to otorhinolaryngology, as well as head and neck surgery (ORL-HNS). 
  • 169
  • 06 Dec 2021
Topic Review
Risk Factors for Recurrent Benign Paroxysmal Positional Vertigo
Benign paroxysmal positional vertigo (BPPV) is the commonest peripheral vestibular condition encountered in a neurotology clinic and it accounts for about 20% to 30% of all the vestibular complaints. The mechanism of BPPV has been based on dislodged otoliths that leave the utricle and freely float in the semicircular canals or attach to the cupula, making the labyrinth sensitive to gravitational forces. BPPV is characterized by recurrent and brief vertigo with corresponding nystagmus when extending or turning the neck, getting up or lying down, or rolling over in bed.
  • 162
  • 29 Jan 2022
Topic Review
Autologous Fat Injection Laryngoplasty for Unilateral Vocal Palsy
Unilateral vocal palsy (UVFP) affects the voice and swallowing function and could be treated by various materials to achieve improved mucosal wave and better closure during phonation. Injection laryngoplasty is considered an exemplary method for these patients and could be injected as early as possible. We conducted a systematic review and meta-analysis for the subjective and objective outcomes of autologous fat injection laryngoplasty (AFIL) and assessed the effects for patients with UVFP. 
  • 158
  • 08 Nov 2021
Topic Review
Molecular Therapeutic Targets for Adenoid Cystic Carcinoma
Adenoid Cystic Carcinoma (ACC) is a rare malignant tumor of the salivary glands. The most researched pathway associated with ACC is the MYB–NFIB translocation, found to lead to dysregulation of critical cellular pathways and thought to be a fundamental driver in a subset of ACC disease pathogenesis. Other notable molecular targets that have been studied include the cKIT receptor, the epidermal growth factor receptor (EGFR) pathway, and NOTCH1, all with limited efficacy in clinical trials. The ongoing investigation of molecular abnormalities underpinning ACC that may be responsible for carcinogenesis is critical to identifying and developing novel targeted therapies.
  • 155
  • 22 Apr 2022
Topic Review
Bilateral Vestibular Dysfunction
Patients with dysfunction of both vestibular systems of the inner ear experience postural instability and gait disturbances.  This condition is called Bilateral Vestibular Dysfunction (BVD). 
  • 146
  • 11 Mar 2022
Topic Review
Nutritional Intervention on Taste Perception
Taste is primarily a nutrient sensing system. The texture of the food and the rate at which it is eaten, have a profound effect on the time of orosensory exposure to foods and to satiation. It has been established that slower eating leads to a longer exposure to taste.
  • 144
  • 29 Mar 2022
Topic Review
Olfactory-Disorders in Post-Acute COVID-19 Syndrome
Altered smell is one of the most prevalent symptoms in acute COVID-19 infection. Although most patients recover normal neurosensory function in a few weeks, approximately one-tenth of patients report long-term smell dysfunction, including anosmia, hyposmia, parosmia and phantosmia, with a particularly notable impact on quality of life. In this complex scenario, inflammation and cellular damage may play a key role in the pathogenesis of olfactory dysfunctions and may affect olfactory signaling from the peripheral to the central nervous system.
  • 131
  • 29 Sep 2021
Topic Review
HRQOL in Oral Cancer Patients
The scope of the present entry was to highlight possible sources of bias that could be encountered when evaluating HRQOL (Health-Related Quality of Life) in patients treated for oral cancer. The second aim was to lay the foundation of a standardized protocol for cohort selection, data collection, and stratification that could enhance knowledge in the field.
  • 130
  • 22 Sep 2021
Topic Review
Sinonasal Inverted Papilloma
Sinonasal inverted papilloma (SNIP) is a benign neoplasm of the nasal cavity and paranasal sinuses and accounts for 0.5–4% of primary nasal tumors.
  • 115
  • 22 Feb 2022
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