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Topic Review
Cementless Total Knee Arthroplasty
Considering the increasing number of young and active patients needing Total Knee Arthroplasty (TKA), orthopedic surgeons are looking for a long-lasting and physiological bond for the prosthetic implant. Multiple advantages have been associated with cementless fixation including higher preservation of the native bone stock, avoidance of cement debris with subsequent potential third-body wear, and the achievement of a natural bond and osseointegration between the implant and the bone that will provide a durable and stable fixation. 
  • 269
  • 18 Mar 2024
Topic Review
Lateral Lumbar Interbody Fusion
Lumbar interbody fusion procedures have seen a significant evolution over the years, with various approaches being developed to address spinal pathologies and instability, including posterior lumbar interbody fusion (PLIF), transforaminal lumbar interbody fusion (TLIF), anterior lumbar interbody fusion (ALIF), and lateral lumbar interbody fusion (LLIF). LLIF, a pivotal technique in the field, initially emerged as extreme/direct lateral interbody fusion (XLIF/DLIF) before the development of oblique lumbar interbody fusion (OLIF). To ensure comprehensive circumferential stability, LLIF procedures are often combined with posterior stabilization (PS) using pedicle screws. 
  • 67
  • 05 Mar 2024
Topic Review
Biofeedback in Patellofemoral Pain Conservative Treatment
atellofemoral pain syndrome is typical of active young adults, manifesting as retro patellar or peripatellar pain. It usually begins slowly and progresses with a gradual increase in pain. Often atraumatic, it has been linked to increased weight bearing on the patellofemoral joint.
  • 54
  • 04 Mar 2024
Topic Review
3D-Printed Porous Titanium Alloy Pore Structure onBone Regeneration
As a biomedical material, porous titanium alloy has gained widespread recognition and application within the field of orthopedics. Its remarkable biocompatibility, bioactivity, and mechanical properties establish it as a promising material for facilitating bone regeneration. A well-designed porous structure can lower the material’s modulus while retaining ample strength, rendering it more akin to natural bone tissue. The repair and replacement of a wide range of bone defects caused by diseases, trauma, and aging has been an important subject for centuries.
  • 41
  • 28 Feb 2024
Topic Review
Pre-Procedure Preparation of Sacroplasty for Sacral Insufficiency Fractures
Sacral insufficiency fractures are disabling injuries that may occur in the absence of trauma, or result from low-energy injuries such as ground level falls. These fractures can cause severe lower back, buttock, and groin pain and are most commonly identified among older women diagnosed with osteoporosis. Sacroplasty is a minimally invasive procedure for treating sacral insufficiency fractures that involves placement of polymethylmethacrylate cement into the sacral ala.
  • 53
  • 27 Feb 2024
Topic Review
Mechanical Considerations in KOA and PTOA Pathogenesis
Knee osteoarthritis (KOA) represents a prevalent and formidable challenge in the management and treatment of musculoskeletal disorders and exerts a substantial impact on global health, particularly in the context of the natural aging process. Post-traumatic osteoarthritis (PTOA) emerges as a distinct clinical manifestation within the realm of osteoarthritis and is interwoven within the landscape of sports injuries and trauma of the joints. Within the realm of sports, athletes are frequently exposed to joint injury and acute mechanical loading that sets the biological stage for the development of PTOA.
  • 132
  • 23 Feb 2024
Topic Review
Therapies in Osteogenesis Imperfecta
Osteogenesis imperfecta (OI) is a rare skeletal dysplasia characterized as a heterogeneous disorder group with well-defined phenotypic and genetic features that share uncommon bone fragility. 
  • 62
  • 22 Feb 2024
Topic Review
Immunotherapy Innovations in the Fight against Osteosarcoma
Immunosuppressive elements within the tumor microenvironment are the primary drivers of tumorigenesis and malignant advancement. The presence, as well as the crosstalk between myeloid-derived suppressor cells (MDSCs), osteosarcoma-associated macrophages (OS-Ms), regulatory T cells (Tregs), and endothelial cells (ECs) with osteosarcoma cells cause the poor prognosis of OS.
  • 140
  • 20 Feb 2024
Topic Review
Biopsy Techniques for Musculoskeletal Tumors
Biopsy is a pivotal component in the diagnostic process of bone and soft tissue tumors. The objective is to obtain adequate tissue without compromising local tumor dissemination and the patient’s survival.
  • 138
  • 17 Feb 2024
Topic Review
COVID-19-Infection- and Steroid-Treatment-Associated Bone Avascular Necrosis
The COVID-19 pandemic has presented numerous challenges to the global healthcare system and emerging evidence suggests a potential link between COVID-19 treatment, specifically steroid therapy, and the development of avascular necrosis (AVN) of the hip. Understanding the nuances of AVN in the context of COVID-19 is crucial for healthcare professionals to navigate treatment decisions and mitigate potential complications.
  • 60
  • 08 Feb 2024
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