Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Graphene Oxide Thin Films with Drug Delivery Function
Graphene oxide has been used in different fields of nanomedicine as a manager of drug delivery due to its inherent physical and chemical properties that allow its use in thin films with biomedical applications. Several studies demonstrated its efficacy in the control of the amount and the timely delivery of drugs when it is incorporated in multilayer films. It has been demonstrated that graphene oxide layers incorporated in drug delivery systems are able to work either as a nanocarrier, transporting the drugs to their targets or as a barrier delaying the release of drugs to accommodate the treatment schedules. This allows for the development of structured ,sophisticated and time-controlled systems.
  • 554
  • 22 Apr 2022
Topic Review
Nerve Stimulation
Nerve stimulation is an effective method to alleviate the negative impacts of neurodegeneration. According to nerve categories, nerve stimulation can be divided into three types—brain stimulation, spinal spur, and peripheral stimulation. All three therapies take similar physical principles to achieve stimulus, while WPT and wireless telecommunication are adopted to maintain a relatively long duration and precise control. 
  • 528
  • 27 Jul 2022
Topic Review
Marine Collagen in Pharmacological, Biomedical, and Regenerative Medicine
Several bioactive compounds of marine origin are being studied, and among these, marine collagen represents one of the most attractive bio-resources, given its use in various disciplines, such as clinical applications, cosmetics, the food sector, and many other industrial applications. The applications of Marine collagen in pharmacological, biomedical fields and regenerative medicine are discussed. 
  • 514
  • 28 Feb 2023
Topic Review
Laboratory Demand Management Strategies
Inappropriate laboratory test selection in the form of overutilization as well as underutilization frequently occurs despite available guidelines. There is broad approval among laboratory specialists as well as clinicians that demand management strategies are useful tools to avoid this issue. Most of these tools, which may be adopted to local settings, are based on automated algorithms or other types of machine learning. We believe that artificial intelligence may help to further improve these available tools.
  • 511
  • 14 Sep 2021
Topic Review
Strength and Weakness of NIBS-RAR Coupled Intervention
Robot-aided rehabilitation (RAR) and non-invasive brain stimulation (NIBS) are the two main interventions for post-stroke rehabilitation. The importance of coupling these interventions, which both enhance brain plasticity to promote recovery, lies in augmenting the rehabilitation potential to constrain the limitation in daily living activities and the quality of life following stroke.
  • 509
  • 08 Dec 2022
Topic Review
Loop-Mediated Isothermal Amplification Technique
The course of periodontal disease is affected by many factors; however, the most significant are the dysbiotic microflora, showing different pathogenicity levels. Rapid colonization in the subgingival environment can radically change the clinical state of the periodontium. This study aims to present an innovative technique of loop-mediated isothermal amplification for rapid panel identification of bacteria in periodontal diseases. The decisive advantage of the loop-mediated isothermal amplification (LAMP) technique in relation to molecular methods based on the identification of nucleic acids (such as polymerase chain reaction (PCR or qPCR) is the ability to determine more pathogens simultaneously, as well as with higher sensitivity. In comparison with classical microbiological seeding techniques, the use of the LAMP method shortens a few days waiting time to a few minutes, reducing the time necessary to identify the species and determine the number of microorganisms. The LAMP technology requires only a small hardware base; hence it is possible to use it in outpatient settings. The developed technique provides the possibility of almost immediate assessment of periodontal status and, above all, risk assessment of complications during the treatment (uncontrolled spread of inflammation), which can certainly be of key importance in clinical work.
  • 499
  • 17 Mar 2021
Topic Review
Novel Characterization in Radiopharmaceutical Preclinical Design
In this entry, the potential of a digital autoradiography system equipped with a super resolution screen has been evaluated to investigate the biodistribution of a 18F-PSMA inhibitor in a prostate cancer mouse model. Twelve double xenograft NOD/SCID mice (LNCAP and PC3 tumours) were divided into three groups according to post-injection time points of an 18F-PSMA inhibitor. Groups of 4 mice were used to evaluate the biodistribution of the radiopharmaceutical after 30-, 60- and 120-min post-injection. Data here reported demonstrated that the digital autoradiography system is suitable to analyse the biodistribution of an 18F-PSMA inhibitor in both whole small-animal bodies and in single organs. The exposure of both whole mouse bodies and organs on the super resolution screen surface allowed the radioactivity of the PSMA inhibitor distributed in the tissues to be detected and quantified. Data obtained by using a digital autoradiography system were in line with the values detected by the activity calibrator. In addition, the image obtained from the super resolution screen allowed a perfect overlap with the tumour images achieved under the optical microscope. In conclusion, biodistribution studies performed by the autoradiography system allow the microscopical modifications induced by therapeutic radiopharmaceuticals to be studied by comparing the molecular imaging and histopathological data at the sub-cellular level. 
  • 465
  • 22 Oct 2021
Topic Review
Influence of Haemolysis
Haemolysis of serum samples is the leading cause of preanalytical errors in clinical laboratories.
  • 417
  • 07 Dec 2021
Topic Review
Polyphenols in Modulating Mitochondrial Bioenergetics
Polyphenols are naturally derived compounds that are increasingly being explored for their various health benefits. In fact, foods that are rich in polyphenols have become an attractive source of nutrition and a potential therapeutic strategy to alleviate the untoward effects of metabolic disorders. The last decade has seen a rapid increase in studies reporting on the bioactive properties of polyphenols against metabolic complications, especially in preclinical models.
  • 412
  • 04 Jun 2021
Topic Review
Uric Acid Electroanalysis
Uric acid is a metabolic product that results from degradation of purines in the liver. Usually, uric acid is identified from biological fluids, human serum and urine through conventional methods, such as spectroscopy, chromatography, electrochemistry, membrane capillary electrophoresis and spectrophotometric methods, including uricase enzymatic reactions. Importantly, uric acid determination opens the possibility of early intervention in cases of hyperuricemia and preventing the degradation of renal function.
  • 409
  • 25 Jun 2023
  • Page
  • of
  • 6
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Feedback