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Topic Review
Fenbendazole Fever
Fenbendazole (FZ) is a benzimidazole carbamate drug with broad-spectrum antiparasitic activity in humans and animals. The mechanism of action of FZ is associated with microtubular polymerization inhibition and glucose uptake blockade resulting in reduced glycogen stores and decreased ATP formation in the adult stages of susceptible parasites. 
  • 2.6K
  • 10 Nov 2022
Topic Review
Medicinal Significance of 1,2,3-Thiadiazoles Derivatives
The 1,2,3-thiadiazole moiety occupies a significant and prominent position among privileged heterocyclic templates in the field of medicine, pharmacology and pharmaceutics due to its broad spectrum of biological activities.
  • 1.5K
  • 19 Jul 2021
Topic Review
Properties of Pistacia lentiscus L.
Pistacia lentiscus L. (PlL) is a wild-growing shrub rich in terpenoids and polyphenols, the oil and extracts of which have been widely used against inflammation and infections, and as wound healing agents.
  • 1.2K
  • 11 May 2021
Topic Review
Natural Language Processing for Telehealth
The natural language processing (NLP) technology can serve as an interaction between computers and humans using linguistic analysis and deep learning methods to obtain knowledge from an unstructured free text. The NLP systems have shown their uniqueness and importance in the areas of information retrieval mostly in the retrieval and processing of large amount of unstructured clinical records and return structured information by user-defined queries. In general, the NLP system is aimed at representing explicitly the knowledge that is expressed by the text written in a natural language. 
  • 1.2K
  • 18 Sep 2021
Topic Review
Commercial Targeted Libraries in Drug Design
After the identification of a biological target (enzyme, receptor, protein and so on), the focus of the early phase of drug discovery rests on the identification of leads or compounds that exhibit pharmacological activity against this specific target. Compounds of interest are most often discovered in pre-existing libraries of compounds that can be either virtual or physical. Computer-aided methods which have become increasingly important over the years in drug development utilize virtual compound libraries. While physical compound libraries reach the number of millions of molecules, virtual compound libraries created by large pharmaceutical companies can range from 107 to 1018 molecules. Investigations of these libraries identifies specific molecules, synthetic pathways and focus on a specific chemical space. Targeted libraries are often smaller and are focused towards a specific chemical space. They are created by using relevant biological information with the aim to decrease the processing time associated with larger libraries while maintaining the most relevant chemical space where lead compounds can be found. Due to the fact that they required less computational or wet-lab labor to process they have become very popular with smaller laboratories which try to compete in the drug-development sector. Many modern vendors of compounds today offer such libraries, but the quality of the procedure used to define desired chemical space and select compounds is questionable.
  • 1.0K
  • 25 May 2022
Topic Review
Film-Forming Systems
Film-forming formulations represent a novel form of sustained release dermatic products. They are applied to the skin as a liquid or semi-solid preparation.
  • 947
  • 30 Jun 2021
Topic Review
Anticancer Activities of Mushrooms
Approximately 270 species of mushrooms have been reported as potentially useful for human health. However, few mushrooms have been studied for bioactive compounds that can be helpful in treating various diseases. Like other natural regimens, the mushroom treatment appears safe, as could be expected from their long culinary and medicinal use.
  • 793
  • 29 Mar 2022
Topic Review
Applications of Artificial Intelligence for Palliative Care
Artificial intelligence (AI) model development for synthetic data generation to improve Machine Learning (ML) methodologies is an integral part of research in Computer Science and is currently being transferred to related medical fields, such as Systems Medicine and Medical Informatics. Palliative care (PC) uses a team-oriented approach to improve the quality of life of patients and their families who are facing problems associated with a life-threatening illness.
  • 694
  • 22 Aug 2022
Topic Review
Avoid Medication Errors, Reporting Systems
Creating an effective multiple-phase reporting method to lower medication errors can act to identify the baseline rates of prescription errors. Hence, this can enable a recognition of the major types of medication errors and thereby assist in risk-reduction through the application of various preventive measures. A successful strategy to prevent and detect drug-related problems may involve three stages: pre-intervention phase, intervention phase, and post-intervention phase. 
  • 677
  • 05 Nov 2021
Topic Review
Computer-Aided Breast Cancer Diagnosis
A computer-aided diagnosis (CAD) expert system is a powerful tool to efficiently assist a pathologist in achieving an early diagnosis of breast cancer. This process identifies the presence of cancer in breast tissue samples and the distinct type of cancer stages. In a standard CAD system, the main process involves image pre-processing, segmentation, feature extraction, feature selection, classification, and performance evaluation. Breast cancer can be distinguished as benign (non-cancerous) and malignant (cancerous/metastatic) tumours. Benign tissue refers to changes in normal tissue of breast parenchyma, which does not relate to the development of malignancy . Contrarily, malignant tissue can be categorised into two types: in-situ carcinoma and invasive carcinoma.  
  • 665
  • 15 Jun 2021
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