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Topic Review
Acute Onset Disaster
Acute onset disasters impact children’s and adolescents’ psychological well-being, often leading to mental health challenges. The way a young person copes with the event plays a significant role in development of post-disaster psychopathology. Coping has been widely studied after acute onset disasters, however, difficulties conducting research in post-disaster contexts and the individualized nature of coping make accurate assessment of coping a significant challenge.
  • 397
  • 19 May 2021
Topic Review
ADHD-Gaming Disorder Comorbidity in Children and Adolescents
Attention Deficit/Hyperactivity Disorder (ADHD) is a neurobiological condition characterized by developmentally inadequate levels of inattention, hyperactivity, and impulsivity, and a neurobiological disruption in brain neurotransmitters and circuitry causing abnormal responses to rewards. Playing electronic games generates a biological response that activates the neuronal circuits linked to pleasure and reward, and there is a growing attention to this type of activity, which can also turn into a mental health condition. With the recognition of ‘Internet Gaming Disorder’ (IGD) as a condition belonging to the broader area of addiction requiring more in-depth study with respect to the DSM-5, while ‘Gaming Disorder’ (GD) was officially recognized as a new diagnosis by the World Health Organization (WHO) in the updated revision of the International Classification of Diseases (ICD-11).
  • 434
  • 18 Oct 2022
Topic Review
Affect and Personality in Fibromyalgia
Fibromyalgia syndrome (FMS) is a chronic disorder characterized by widespread and persistent musculoskeletal pain, which is usually associated with other symptoms such as fatigue, tiredness, insomnia, stiffness, cognitive deficits, and emotional comorbidities (i.e., depression and anxiety). FMS patients usually display a high rate of psychiatric disorders compared to the general population. FMS has been also associated with higher levels of negative affect and lower levels of positive affect. High levels of stress, pain catastrophizing, and angry rumination have been also reported in FMS patients. Additionally, there are a tendency to internalize and suppress anger in FMS patients. Regarding personality in FMS, some studies have observed some FMS features (e.g., high impulsivity, harm avoidance, self-transcendence and neuroticism, and low conscientiousness, cooperativeness and self-directedness), while other authors had not found any particular personality trait. Some personality disorders (i.e., obsessive-compulsive personality disorder, borderline personality, avoidant personality disorder, and histrionic personality disorder) seem to be more frequent in FMS patients than in general population. Moreover, previous research has reported a greater presence of the type D personality and high levels of alexithymia in a significant proportion of FMS patients. It is necessary to improve the understanding of the role of affect and personality in the clinical practice with chronic pain patients, in order to improve the success of a personalized oriented treatment and increase their health-related quality of life.
  • 6.1K
  • 27 Oct 2020
Topic Review
AI Agent Model for Extrinsic Emotion Regulation
Emotion regulation is the human ability to modulate one’s or other emotions to maintain emotional well-being. Despite its importance, only a few computational models have been proposed for facilitating emotion regulation. To address this gap, a computational model for intelligent agents has been proposed for facilitating emotion regulation in individuals. This model is grounded in a multidimensional emotion representation and on J. Gross’s theoretical framework of emotion regulation. In this apporach, an intelligent agent selects the most appropriate regulation strategies to reach or maintain an individual’s emotional equilibrium considering the individual’s personality traits and specific characteristics.
  • 91
  • 11 Mar 2024
Topic Review
Alcohol Craving
Craving is a multidimensional phenomenon involving an intense urge to consume substances. It is perceived as an individual experience of “wanting” a drug that may result in motivational and drug-seeking behavioral patterns. Alcohol craving has been extensively studied due to its clinical implications in the development and maintenance of alcohol use disorder (AUD). Craving is considered one of the mechanisms that promote relapse after treatment discharge and even after a prolonged period of abstinence. To better understand the magnitude of the relationship between craving and relapse, it is fundamental to explore factors associated with alcohol craving as it may help in the development of more efficient treatment approaches to prevent relapse in AUD patients.
  • 1.1K
  • 28 Sep 2020
Topic Review
Antipsychotic Use in Pregnancy
Pregnant women constitute a vulnerable population, with 25.3% of pregnant women classified as suffering from a psychiatric disorder. Since childbearing age typically aligns with the onset of mental health disorders, it is of utmost importance to consider the effects that antipsychotic drugs have on pregnant women and their developing fetus. However, the induction of pharmacological treatment during pregnancy may pose significant risks to the developing fetus. Antipsychotics are typically introduced when the nonpharmacologic approaches fail to produce desired effects or when the risks outweigh the benefits from continuing without treatment or the risks from exposing the fetus to medication. Early studies of pregnant women with schizophrenia showed an increase in perinatal malformations and deaths among their newborns. Similar to schizophrenia, women with bipolar disorder have an increased risk of relapse in antepartum and postpartum periods.
  • 347
  • 24 Jan 2022
Topic Review
Attention Deficit Hyperactivity Disorder
Attention-deficit Hyperactivity Disorder is one of the most common childhood mental health disorders, affecting about 5.6% of the population worldwide.
  • 462
  • 15 Jan 2022
Topic Review
Basic Symptoms of Schizophrenia
Basic symptoms of schizophrenia are subjective symptoms, described as experienced from a person's perspective, which show evidence of underlying psychopathology. Basic symptoms have generally been applied to the assessment of people who may be at risk to develop psychosis. Though basic symptoms are often disturbing for the person, problems generally do not become evident to others until the person is no longer able to cope with their basic symptoms. Basic symptoms are more specific to identifying people who exhibit signs of prodromal psychosis (prodrome) and are more likely to develop schizophrenia over other disorders related to psychosis. Schizophrenia is a psychotic disorder, but is not synonymous with psychosis. In the prodrome to psychosis, uncharacteristic basic symptoms develop first, followed by more characteristic basic symptoms and brief and self-limited psychotic-like symptoms, and finally the onset of psychosis. People who were assessed to be high risk according to the basic symptoms criteria have a 48.5% likelihood of progressing to psychosis. In 2015, the European Psychiatric Association issued guidance recommending the use of a subscale of basic symptoms, called the Cognitive Disturbances scale (COGDIS), in the assessment of psychosis risk in help-seeking psychiatric patients; in a meta-analysis, COGDIS was shown to be as predictive of transition to psychosis as the Ultra High Risk (UHR) criteria up to 2 years after assessment, and significantly more predictive thereafter. The basic symptoms measured by COGDIS, as well as those measured by another subscale, the Cognitive-Perceptive basic symptoms scale (COPER), are predictive of transition to schizophrenia.
  • 272
  • 08 Nov 2022
Topic Review
Biomarkers for Pediatric Depressive Disorders
Depressive disorder in childhood and adolescence is a highly prevalent mood disorder that tends to recur throughout life. Untreated mood disorders can adversely impact a patient’s quality of life and cause socioeconomic loss. Thus, an accurate diagnosis and appropriate treatment is crucial. However, until now, diagnoses and treatments were conducted according to clinical symptoms. Objective and biological validation is lacking. This may result in a poor outcome for patients with depressive disorder. Research has been conducted to identify the biomarkers that are related to depressive disorder. Cumulative evidence has revealed that certain immunologic biomarkers including brain-derived neurotrophic factor (BDNF) and cytokines, gastrointestinal biomarkers, hormones, oxidative stress, and certain hypothalamus-pituitary axis biomarkers are associated with depressive disorder.
  • 525
  • 09 Oct 2021
Topic Review
Bremelanotide
Bremelanotide is a melanocortin receptor agonist which non-selectively activates melanocortin 1 receptor (MC1R), melanocortin 2 receptor (MC2R), melanocortin 3 receptor (MC3R), melanocortin 4 receptor (MC4R), and melanocortin 5 receptor (MC5R) receptors.
  • 444
  • 17 Jan 2022
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