Topic Review
Grandidier's Mongoose
Grandidier's mongoose (Galidictis grandidieri) (Figure 1) is a rare and elusive carnivore native to Madagascar. Named after the French naturalist Alfred Grandidier, this mongoose species is distinguished by its slender body, short legs, and long, bushy tail. Endemic to Madagascar's dry deciduous forests, Grandidier's mongoose is known for its solitary and nocturnal habits, making it a challenging species to study in its natural habitat.
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Topic Review
Harp Seal
The Harp Seal, also known by its scientific name Phoca groenlandica, is a marine mammal renowned for its striking appearance and unique life history. Recognized by the distinctive black harp-shaped markings on its coat, the Harp Seal inhabits the icy waters of the North Atlantic and Arctic Oceans. This species undergoes remarkable migrations and breeding events, with large aggregations congregating on ice floes each spring to give birth and nurse their pups.
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Topic Review
Gray Seal
The Gray Seal, scientifically known as Halichoerus grypus, is a marine mammal renowned for its distinctive appearance and widespread distribution across the North Atlantic Ocean. Characterized by its robust build, long whiskers, and mottled gray fur, the Gray Seal is a highly adaptable species found inhabiting coastal waters, rocky shores, and sandy beaches from Canada to Europe. As a top predator in marine ecosystems, the Gray Seal plays a crucial role in regulating prey populations and maintaining ecosystem balance.
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Topic Review
Kodkod
The Kodkod, scientifically known as Leopardus guigna, is a small wild cat species native to the temperate forests of South America. It is one of the smallest wild cats in the Americas, with adults typically weighing between 2 to 3 kilograms. Despite its diminutive size, the Kodkod is a skilled predator, preying on small mammals, birds, and insects, and plays a crucial role in maintaining ecosystem balance within its habitat.
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Topic Review
South American Gray Fox
The South American Gray Fox, scientifically known as Lycalopex griseus, is a captivating canid species native to South America. Renowned for its sleek gray fur and bushy tail, this fox inhabits a variety of habitats, from grasslands and scrublands to forests and urban areas. As an adaptable omnivore, the South American Gray Fox plays a crucial role in its ecosystem by regulating prey populations and participating in seed dispersal, contributing to the overall balance of its environment.
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Topic Review
Pathophysiology of Secondary Acute Myeloid Leukemia
Secondary acute myeloid leukemia (sAML) is a heterogeneous malignant hematopoietic disease that arises either from an antecedent hematologic disorder (AHD) including myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), aplastic anemia (AA), or as a result of exposure to genotoxic chemotherapeutic agents or radiotherapy (therapy related AML, tAML). sAML is diagnosed when the number of blasts is ≥20% in the bone marrow or peripheral blood, and it is characterized by poor prognosis, resistance to therapy and low overall survival rate. 
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Topic Review
Common Genet
The Common Genet, also known as Genetta genetta, is a small carnivorous mammal native to Europe and parts of North Africa. Recognizable by its slender body, long tail, and distinctive facial markings, the Common Genet is a nocturnal hunter, preying on small mammals, birds, reptiles, and insects. Despite its name, the Common Genet is not closely related to cats but belongs to the family Viverridae, making it a unique and intriguing member of the carnivore community.
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Topic Review
Antarctic Fur Seal
The Antarctic Fur Seal, scientifically known as Arctocephalus gazella, is a charismatic marine mammal native to the subantarctic and Antarctic regions. Recognized for its dense fur coat, robust build, and distinctive facial features, this species is a top predator in its icy habitat. Antarctic Fur Seals play a vital role in marine ecosystems, influencing prey populations and contributing to the overall health of polar environments.
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Topic Review
Galapagos Fur Seal
The Galapagos Fur Seal, scientifically known as Arctocephalus galapagoensis, is a marine mammal endemic to the Galapagos Islands. With its dense, dark brown fur and slender physique, this species is well-adapted to its coastal habitat. Despite its name, the Galapagos Fur Seal is not a true seal but rather belongs to the fur seal family, Otariidae, distinguishing it by its ability to rotate its hind flippers forward for efficient movement on land.
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Topic Review
Glypican-Regulated Transport and Gradient Formation in Drosophila
Glypicans (Glps) are a family of heparan sulphate proteoglycans that are attached to the outer plasma membrane leaflet of the producing cell by a glycosylphosphatidylinositol anchor. Glps are involved in the regulation of many signalling pathways, including those that regulate the activities of Wnts, Hedgehog (Hh), Fibroblast Growth Factors (FGFs), and Bone Morphogenetic Proteins (BMPs), among others. In the Hh-signalling pathway, Glps have been shown to be essential for ligand transport and the formation of Hh gradients over long distances, for the maintenance of Hh levels in the extracellular matrix, and for unimpaired ligand reception in distant recipient cells. 
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