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Topic Review
Biography
Topic Review
Guzmania monostachia
in Florida Rests with Humans
Land use changes by humans have eliminated more than half of the wetlands in Florida over the last 200 years, and additional losses are anticipated as a consequence of climate change and ongoing development activities that will accommodate a rapidly growing human population. Both spell danger for the biodiversity and ecosystem services in Florida, and data are needed to inform conservation priorities and actions concerning threatened or endangered wetland species.
227
20 Oct 2023
Topic Review
Han:SPRD
Rat as Preclinical Model of Polycystic Kidney
Autosomal Dominant Polycystic Kidney Disease (ADPKD) stands as the most prevalent hereditary renal disorder in humans, ultimately culminating in end-stage kidney disease. Animal models carrying mutations associated with polycystic kidney disease have played an important role in the advancement of ADPKD research. The Han:SPRD rat model, carrying an R823W mutation in the Anks6 gene is a well-documented animal model of inherited PKD with an autosomal dominant pattern of inheritance, closely mirroring several features of human ADPKD, including renal hyperplasia, azotemia, and extrarenal manifestations. The mutated protein, named Samcystin, is localized in cilia of tubular epithelial cells and seems to be involved in cystogenesis. The homozygous Anks6 mutation leads to end-stage renal disease and death, making it a critical factor in kidney development and function.
186
29 Feb 2024
Topic Review
Helichrysum arenarium
Helichrysum arenarium (L.) Moench, belonging to the Asteraceae family, is known in traditional medicine for its diuretic, choleretic, and anti-inflammatory properties. Helichrysum arenarium (sandy everlasting) is a source of active pharmacological compounds used in complementary medicine to prevent digestive and hepatobiliary illnesses.
1.7K
21 Oct 2022
Topic Review
Helicobacter pylori
and Neurodegenerative Diseases
Phytochemicals are plant secondary metabolites that show health benefits for humans due to their bioactivity. There is a huge variety of phytochemicals that have already been identified, and these compounds can act as antimicrobial and neuroprotection agents. Due to their anti-microbial activity and neuroprotection, several phytochemicals might have the potency to be used as natural therapeutic agents, especially for Helicobacter pylori infection and neurodegenerative disease, which have become a global health concern nowadays.
355
01 Nov 2023
Topic Review
Helicobacter pylori
in oral cavity from ITP patient
Immune thrombocytopenic purpura (ITP) is an autoimmune disease characterized by isolated cryptogenic thrombocytopenia due to a transient or persistent reduction in platelet count. However, there have been no studies regarding H. pylori in the oral cavity of patients with ITP. Here, we describe a patient with ITP whose oral samples exhibited H. pylori. A 64-year-old woman with ITP came to our hospital with chief complaints that required oral surgery, including tooth extraction and cystectomy. Bacterial DNA of H. pylori was confirmed on the extracted tooth, but was not detected in saliva taken at the time. Bacterial DNA of H. pylori was detected on the suture around the extraction socket, which was removed at 10 days postoperatively. However, H. pylori DNA was not detected in other oral samples at 10 or 30 days postoperatively. The urea breath test was carried out in the gastrointestinal clinic at 60 days postoperatively, which revealed no presence of H. pylori in the gastrointestinal tract. These results suggest that teeth with severe bacterial infections may be a potential reservoir of H. pylori of patients with ITP.
468
15 Nov 2022
Topic Review
Helicobacter pylori
infection, pathogenicity, and therapeutic advances
A primer on Helicobacter pylori virulence factors, pathogenicity, gastric conditions that are caused by infection, and treatment modalities. This entry is adapted from the peer-reviewed paper 10.3390/pathogens13050392
470
17 May 2024
Topic Review
Humulus lupulus
L. By-Products
Hops (Humulus lupulus L.) are known worldwide as a raw material in beer production due their flavor and preservative values. The beneficial properties of the plant have been mostly associated with the female hop inflorescences (cones), which is also the part used in the brewing industry. However, some studies indicate the presence of compounds associated with health benefits in the vegetative parts of hops or small-caliber cones, which discarded in hop collection. Moreover, large quantities of by-products remain in the forms of spent grains and spent hops/hot trub and are produced by breweries raising environmental and economic sustainability concerns.
535
22 Dec 2022
Topic Review
Hyacinthus orientalis
L.
Hyacinthus orientalis L., commonly known as hyacinth, is one of the most important cultivated plants around the world. The cultivars of this species are characterised by their flowers with strong fragrances and a wide range of attractive colours, which make them a beloved option among ornamentals. The chloroplast genomes of Hyacinthus cultivars ranged from 154,458 bp to 154,641 bp, while those of Bellevalia paradoxa and Scilla siberica were 154,020 bp and 154,943 bp, respectively. Each chloroplast genome was annotated with 133 genes, including 87 protein-coding genes, 38 transfer RNA genes and 8 ribosomal RNA genes.
1.3K
17 Jun 2022
Topic Review
Hyalomma
Ticks and Human and Animal Health
Ticks are obligatory hematophagous ectoparasites that act as vectors for many important human and livestock pathogens worldwide. Like spiders and scorpions, they belong to the class Arachnida. Within the order Ixodida, most species of ticks belong to one of the two main large families, Argasidae or Ixodidae. The latter are known as “hard” ticks since they have a sclerotized dorsal plaque or scutum. In contrast, those belonging to the family Argasidae lack this physical feature and are therefore known as “soft ticks”. Tick-borne infectious diseases spread following the bite of infected ticks, which can carry and be infected by bacteria, viruses, or parasites. Some of the most important bacteria-infecting ticks include species of the genera Rickettsia, Borrelia, Francisella, Anaplasma, and Ehrlichia, as well as viruses such as the Crimea–Congo hemorrhagic fever (CCHF) virus, the West Nile virus, and the tick-borne encephalitis virus, among others.
518
05 May 2023
Topic Review
Juglans regia
Linn.
Juglans regia Linn. belongs to the family Juglandaceae and is an aromatic transient tree that grows in abundance in the North-Western Himalayas of Kashmir that produces most of the world’s walnuts, accounting for around 88% of total walnut production.
540
08 Feb 2023
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