Topic Review
Valorization of Brewers’ Spent Grains
Brewers’ spent grains constitute a valuable byproduct of the beer industry. They are characterized by a rich nutritional composition consisting of around 70% lignocellulosic fibrous material, 20% proteins, 10% lipids, in addition to vitamins, minerals, amino acids, and phenolic compounds.
  • 904
  • 25 Feb 2022
Topic Review
Valorization of Agro-Food Industrial Residues by Solid-State Fermentation
Agro-food industrial residues (AFIRs) are generated in large quantities all over the world. The vast majority of these wastes are lignocellulosic wastes that are a source of value-added products. Technologies such as solid-state fermentation (SSF) for bioconversion of lignocellulosic waste, based on the production of a wide range of bioproducts, offer both economic and environmental benefits. The versatility of application and interest in applying the principles of the circular bioeconomy make SSF one of the valorization strategies for AFIRs that can have a significant impact on the environment of the wider community.
  • 473
  • 07 Nov 2022
Biography
Valeri Kubasov
Valeri Nikolayevich Kubasov (Russian: Вале́рий Никола́евич Куба́сов; 7 January 1935 – 19 February 2014) was a Soviet/Russia n cosmonaut who flew on two missions in the Soyuz programme as a flight engineer: Soyuz 6 and Soyuz 19 (the Apollo–Soyuz mission), and commanded Soyuz 36 in the Intercosmos programme. On 21 July 1975, the Soyuz 7K-TM module used for ASTP lande
  • 437
  • 30 Nov 2022
Topic Review
Vaginal Discharge
Vaginal discharge is a mixture of liquid, cells, and bacteria that lubricate and protect the vagina. This mixture is constantly produced by the cells of the vagina and cervix, and it exits the body through the vaginal opening. The composition, amount, and quality of discharge varies between individuals and can vary throughout the menstrual cycle and throughout the stages of sexual and reproductive development. Normal vaginal discharge may have a thin, watery consistency or a thick, sticky consistency, and it may be clear or white in color. Normal vaginal discharge may be large in volume but typically does not have a strong odor, nor is it typically associated with itching or pain. While most discharge is considered physiologic or represents normal functioning of the body, some changes in discharge can reflect infection or other pathological processes. Infections that may cause changes in vaginal discharge include vaginal yeast infections, bacterial vaginosis, and sexually transmitted infections. The characteristics of abnormal vaginal discharge vary depending on the cause, but common features include a change in color, a foul odor, and associated symptoms such as itching, burning, pelvic pain, or pain during sexual intercourse.
  • 10.7K
  • 14 Nov 2022
Topic Review
Vaginal Aging
The aging of the organism is a complex and multifactorial process. It can be viewed in the context of the whole organism, but also of individual tissues and organs. The problem of vaginal aging and the related genitourinary syndrome of menopause significantly reduces the quality of women’s lives. The aging process of the vagina includes estrogen deficiencies, changes in the microbiome, and changes at the genetic level associated with DNA methylation. During the menopause, the number of Lactobacillus colonies decreases, and the number of pathological bacteria colonies increases. The decrease in estrogen levels results in a decrease in vaginal epithelial permeability, perfusion, and elastin levels, resulting in vaginal dryness and atrophy. Changes at the molecular level are the least clear. It can also be assumed that, similarly to the tissues studied so far, there are changes in cytosine methylation and TET (ten-eleven translocation) expression. The interrelationships between DNA methylation, hormonal changes, and the vaginal microbiome have not yet been fully elucidated.
  • 619
  • 11 Jun 2021
Topic Review
Vacuolar Processing Enzymes in Plant Programmed Cell Death
Vacuolar processing enzymes (VPEs), which can also be named asparaginyl endopeptidases (AEPs), legumains, or colloquially, plant caspases, as they perform caspase-1-like/YVADase activity, are widespread in the plant kingdom. Their occurrence has been found in lower and higher plants. VPEs are plant cysteine proteases that are subjected to autoactivation in an acidic pH. It is presumed that VPEs, by activating other vacuolar hydrolases, are in control of tonoplast rupture during programmed cell death (PCD). Involvement of VPEs has been indicated in various types of plant PCD related to development, senescence, and environmental stress responses. 
  • 477
  • 20 Jan 2023
Topic Review
VACTERL Association
VACTERL association is a disorder that affects many body systems. VACTERL stands for vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula, renal anomalies, and limb abnormalities.
  • 330
  • 23 Dec 2020
Topic Review
Vaccinium vitis-idaea L.
Lingonberry (Vaccinium vitis-idaea L.; family Ericaceae), otherwise known as cowberry, partridgeberry, and foxberry, is an evergreen dwarf shrub with underground rhizomes widely distributed throughout Northern, Central European, Canadian, and Russian countries’ forests. Due to the promising health benefits, mainly associated with the high content of secondary metabolites—phenolics and triterpenoids—lingonberry leaves acquired prominent pharmaceutical potential and breeding value 
  • 611
  • 27 Sep 2021
Topic Review
Vaccinium Species: Composition and Activity
The genus Vaccinium L. (Ericaceae) includes more than 450 species, which grow mainly in cooler areas of the northern hemisphere. Vaccinium species have been used in the traditional medicine of different cultures and the berries are widely consumed as food. Indeed, Vaccinium supplements-based herbal medicine and functional food, mainly from V. myrtillus and V. macrocarpon, are used in Europe and North America. Biological studies support traditional uses since for many of Vaccinium components important biological functions have been described, including antioxidant, antitumor, anti-inflammatory, antidiabetic, and endothelium protective activities. Vaccinium components, such as polyphenols, anthocyanins, and flavonoids, are widely recognized as modulators of cellular pathways involved in pathological conditions, thus indicating that Vaccinium may be an important source of bioactive molecules. 
  • 624
  • 14 Jul 2021
Topic Review
Vaccinium myrtillus L. in Baltic-Nordic Region
Bilberry (Vaccinium myrtillus L.) is a natural resource and a useful wild berry in Europe. Various parts of the plant contain many benefits for human health. The adaptation and secondary metabolism of V. myrtillus plants can be synergistically affected by a community of microbial endophytes.
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  • 07 Feb 2022
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