Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Innate Immune System in the Cancer
Ionizing radiation therapy is an important component of cancer treatment. Researchers provide a summary of the latest advancements, clinical use, and limitations of radiation therapy. Moreover, researchers explored how radiation affects the body’s natural defense system, which plays a crucial role in fighting cancer. The immune responses triggered by radiation therapy help the body eliminate tumors naturally.
  • 292
  • 16 Aug 2023
Topic Review
Plant–Nanoparticle Interactions
The relationship between plants and nanoparticles (NPs) has been the subject of extensive research interest. Nanoparticles and their interactive effects on plants have raised concern regarding their harmful aspects. There are complex mechanisms evolved in plants for controlling the uptake, accumulation, and mobilization of nanoparticles that need to be discussed further, especially in the context of proteomics and genetic level.
  • 566
  • 16 Aug 2023
Topic Review
Human SRC Homology 3 Domains
SRC homology 3 (SH3) domains are fundamental modules that enable the assembly of protein complexes through physical interactions with a pool of proline-rich/noncanonical motifs from partner proteins. They are widely studied modular building blocks across all five kingdoms of life and viruses, mediating various biological processes. The SH3 domains are also implicated in the development of human diseases, such as cancer, leukemia, osteoporosis, Alzheimer’s disease, and various infections.
  • 464
  • 16 Aug 2023
Topic Review
Medicinal Plants and Cultivable Endophyte Resources
With the increasing demand for medicinal plants and the increasing shortage of resources, improving the quality and yield of medicinal plants and making more effective use of medicinal plants has become an urgent problem to be solved. During the growth of medicinal plants, various adversities can lead to nutrient loss and yield decline. Using traditional chemical pesticides to control the stress resistance of plants will cause serious pollution to the environment and even endanger human health.
  • 237
  • 16 Aug 2023
Topic Review
Cholesterol-Dependent Effects of Statins
Retrospective studies of common malignancies such as head and neck cancer often report lower incidence and/or better outcomes for patients incidentally treated with statins, the HMG-CoA reductase inhibitors commonly prescribed to reduce blood cholesterol and related cardiovascular risks. Lipophilic statins have been proposed to both sensitize to therapy and spare normal tissue, suggesting particular benefits in head and neck cancer, where treatment often incurs major toxicities. While roles for statins in prevention remain controversial, rigorous laboratory studies have confirmed the direct effects of statins on cells and tumors that enhance response to chemotherapy, radiation, targeted agents and immunotherapy.
  • 361
  • 16 Aug 2023
Topic Review
Proteins of the Nucleolus of Dictyostelium discoideum
The nucleolus is a multifunctional subnuclear compartment that has been studied for more than 200 years. The nucleoli of Dictyostelium discoideum have a comparatively unique, non-canonical, localization adjacent to the inner nuclear membrane. The verified nucleolar proteins of this eukaryotic microbe are detailed while other potential proteins are introduced. Heat shock protein 32 (Hsp32), eukaryotic translation initiation factor 6 (eIF6), and tumour necrosis factor receptor-associated protein 1 (TRAP1) are essential for cell survival. NumA1, a breast cancer type 1 susceptibility protein-C Terminus domain-containing protein linked to cell cycle, functions in the regulation of nuclear number. 
  • 324
  • 16 Aug 2023
Topic Review
Types of Collagens
Collagen, a widely recognized extracellular matrix protein, has found extensive use in medical, pharmaceutical, and cosmetic applications. This is due to its crucial role in tissue and organ formation, and its involvement in various cellular functions. Additionally, collagen serves as an effective surface-active agent and displays its capacity to permeate lipid-free interfaces. In comparison to other natural polymers like albumin and gelatin, collagen showcases exceptional biodegradability, minimal antigenicity, and remarkable biocompatibility.
  • 707
  • 16 Aug 2023
Topic Review
Exploitation of Neutrophil Functions to Combat Disease
Neutrophils are crucial innate immune cells and comprise 50–70% of the white blood cell population under homeostatic conditions. Upon infection and in cancer, blood neutrophil numbers significantly increase because of the secretion of various chemo- and cytokines by, e.g., leukocytes, pericytes, fibroblasts and endothelial cells present in the inflamed tissue or in the tumor microenvironment (TME). The function of neutrophils in cancer has recently gained considerable attention, as they can exert both pro- and anti-tumorigenic functions, dependent on the cytokine milieu present in the TME. Here, several promising therapeutic options are addressed, such as cytokine therapy, immunocytokines and immunotherapy, which aim to exploit the anti-tumorigenic potential of neutrophils in cancer treatment or block excessive neutrophil-mediated inflammation in autoimmune diseases.
  • 235
  • 16 Aug 2023
Topic Review
Role of Mitochondria in Somatic Stem Cell Differentiation
While mitochondrial biogenesis has been previously demonstrated in number of differentiation models, it is only recently that the role of mitochondrial dynamics has started to be explored. The discovery of asymmetric distribution of mitochondria in stem cell progeny has strengthened the interest in the field.
  • 227
  • 16 Aug 2023
Topic Review
Klebsiella pneumoniae in Clinical Settings and the Environment
The increasing reports of multidrug-resistant Klebsiella pneumoniae have emerged as a public health concern, raising questions about the potential routes for the evolution and dissemination of the pathogenic K. pneumoniae into environmental reservoirs. Potential drivers of the increased incidence of antimicrobial-resistant environmental K. pneumoniae include the eminent global climatic variations as a direct or indirect effect of human activities. 
  • 431
  • 16 Aug 2023
  • Page
  • of
  • 1815
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
ScholarVision Creations
Feedback