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Topic Review
Biological Potential of Nutraceuticals to Preventing Noncommunicable Diseases
Food plays a fundamental role in the maintenance of health. Particularly, the lack of a good diet leads to the development of several noncommunicable diseases (NCDs), such as cardio-metabolic dysfunction, overweight, obesity, diabetes, cancer, diabetes, etc. It is important to acquire information about natural food sources and food supplements, as they are a source of beneficial nutrients that sustain health.
  • 140
  • 07 Sep 2023
Topic Review
Oxidative Stress in Liver
The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which not only arise during metabolic functions but also during the biotransformation of xenobiotics. The disruption of redox balance causes oxidative stress, which affects liver function, modulates inflammatory pathways and contributes to disease.
  • 254
  • 07 Sep 2023
Topic Review
Drought-Induced Changes in Plant Morphology
Drought stress is the most challenging issue to agricultural productivity and has a pronounced negative effect on plant growth, development, and productivity. Drought stress adversely affects morphological aspects of plants, such as early germination, plant height, relative root length, root diameter, the total biomass of leaves and roots, number of leaves/plants, and branch number/plant.
  • 2.6K
  • 06 Sep 2023
Topic Review
Genetic Requirement for Minimal Genome
Genome reduction is a top-down approach to achieve the minimal genetic information essential for a living cell. Exploring the minimal genetic requirements for cells to maintain free living is an exciting topic in biology. Multiple approaches are employed to address the question of the minimal genome. In addition to constructing the synthetic genome in the test tube, reducing the size of the wild-type genome is a practical approach for obtaining the essential genomic sequence for living cells. The well-studied Escherichia coli has been used as a model organism for genome reduction owing to its fast growth and easy manipulation.
  • 200
  • 06 Sep 2023
Topic Review
AFM Investigation of Protein Crystals Morphology
Atomic force microscopy (AFM) enables the visualization of soft samples over a wide size range, from hundreds of micrometers up to the molecular level. The nonperturbative nature, the ability to scan in a liquid environment, and the lack of need for freezing, fixing, or staining make AFM a well-suited tool for studying fragile samples such as macromolecular crystals. The achievements of AFM underlined start from the study of crystal growth processes studying the surface morphology of protein crystals, passes through the in-depth analysis of the S-layer systems, and arrive at the introduction of the high-speed atomic force microscopy (HS-AFM) that allows the observation of molecular dynamics adsorption.
  • 255
  • 06 Sep 2023
Topic Review
Genetic Engineering in Bacillus 
Due to the increase in the global population, there is an urgent call to enhance the crop production through sustainable agriculture. Biological control is a possible solution. There are many examples of biological control agents applied to different crops that have improved their yield or quality, including vegetable and fruit crops and ornamental plants. The Bacillus species have been used as powerful tools since they suppress plant pathogens and promote plant growth as well. B. thuringiensis has been used as biopesticide in several crops. 
  • 256
  • 06 Sep 2023
Topic Review
Epigenetics and Alzheimer’s Disease and Parkinson’s Disease
Chronic neurodegenerative disorders are believed to be caused by a combination of multiple events that damage neuronal function. Alzheimer’s disease (AD) is the most common neurodegenerative disorder, and Parkinson’s disease (PD) is the second-most common neurodegenerative disorder worldwide. Epigenetics is defined as the stable inheritance of a phenotype, resulting from changes in the chromosomal DNA without mutations in the nucleotide sequence. A number of epigenetic research has revealed that the modification of histones accompanied by both a local and global remodeling of the chromatin structure and alternations in the transcriptional patterns are closely associated with the pathogenesis of neurodegenerative diseases, including AD and PD. 
  • 296
  • 06 Sep 2023
Topic Review
Health-Promoting Benefits of Vegetable Oils
Vegetable oil is an indispensable ingredient in the human daily life diet, not only due to its sensory attributes when used as a cooking medium, but also as an supply energy to maintain body normal temperature. Vegetable oils (VOs) provide essential fatty acids (EFAs) which serve as carriers for liposoluble vitamins, act as precursors for steroid hormones and prostaglandins synthesis, and play a significant role in health protection and disease prevention.
  • 423
  • 06 Sep 2023
Topic Review
The Application of Electrospun Nanofibers in Wound Dressings
Electrospun nanofiber membranes (NFMs) have high porosity and a large specific surface area, which provide a suitable environment for the complex and dynamic wound healing process and a large number of sites for carrying wound healing factors. The design of the nanofiber structure can imitate the structure of the human dermis, similar to the natural extracellular matrix, which better promotes the hemostasis, anti-inflammatory and healing of wounds. 
  • 303
  • 06 Sep 2023
Topic Review
Pathogenesis and Therapeutics for Huntington’s Disease
Huntington’s disease (HD) is a debilitating neurodegenerative genetic disorder caused by an expanded polyglutamine-coding (CAG) trinucleotide repeat in the huntingtin (HTT) gene. HD behaves as a highly penetrant dominant disorder likely acting through a toxic gain of function by the mutant huntingtin protein. Widespread cellular degeneration of the medium spiny neurons of the caudate nucleus and putamen are responsible for the onset of symptomology that encompasses motor, cognitive, and behavioural abnormalities. 
  • 297
  • 06 Sep 2023
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