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Topic Review
FBLN5 Gene
Fibulin 5: The FBLN5 gene provides instructions for making a protein called fibulin-5. 
  • 1.3K
  • 25 Dec 2020
Topic Review
Cytokines Drive Angiogenesis
Cytokines are important molecular players in cancer development, progression, and potential targets for treatment. Despite being small and overlooked, research has revealed that cytokines influence cancer biology in multiple ways. Cytokines are often found to contribute to immune function, cell damage, inflammation, angiogenesis, metastasis, and several other cellular processes important to tumor survival. Cytokines have also proven to have powerful effects on complex tumor microenvironment molecular biology and microbiology.  Angiogenesis, also termed neovascularization, is blood vessel development from pre-existing vasculature. It is regulated by a careful balance of pro- and anti-angiogenic factors.
  • 1.3K
  • 10 May 2022
Topic Review
Interleukin-4 and Interleukin-13 Induced Atopic Dermatitis
Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with widespread barrier dysfunction and T helper 2 (Th2) cytokines. AD is an imbalance in the Th2 immune response where there is an increase in the gene expression levels of major Th2 cytokines during the acute phase.
  • 1.3K
  • 07 Mar 2022
Topic Review
Thermal Load and Heat Transfer in Dental Implants
Heat is a kinetic process whereby energy flows from between two systems, hot-to-cold objects. In oro-dental implantology, conductive heat transfer/(or thermal stress) is a complex physical phenomenon to analyze and consider in treatment planning. Hence, ample research has attempted to measure heat-production to avoid over-heating during bone-cutting and drilling for titanium (Ti) implant-site preparation and insertion, thereby preventing/minimizing early (as well as delayed) implant-related complications and failure. The goal is two-fold: (A) the standard heat equation is proposed to be solved, modifying the imposed boundary conditions without any additional source term, and on the other hand, (B) a gap is filled in the literature via obtaining an exact analytical solution of a somewhat simplified problem, which nevertheless, encapsulates the physics and reproduces the results already found in previous works via numerical analyses. In addition, for the first time, the intrinsic time is introduced and involved herein, a “proper” time that characterizes the geometry of the dental implant fixture and overall system, and how the interplay between that time and the exposure time influences temperature changes, and subsequent implant survival, are shown. Thus, this work aims to complement the overall clinical diagnostic and treatment plan for enhanced biological one–implant interface and mechanical implant stability and success rates, whether for immediate or delayed implant loading strategies.
  • 1.3K
  • 11 Mar 2022
Topic Review
Pollen Quality Versus Quantity
Do bees really benefit from the conservation attempts made by us? A study performed recently showed that wild bees do not use plant species sown in wildflower seed mixtures as pollen sources, and it concluded that plant species currently promoted by agri-environmental schemes are not optimal for bees. I have taken a closer look at the factors that determined whether pollen was healthy food for the wild bee larvae or not and the results have led me to propose that a major shift in the perspective of what we considered as bee-friendly plants was definitely warranted.
  • 1.3K
  • 30 Oct 2020
Biography
Sarah Haider
Sarah Haider is a Pakistani-American writer, speaker, and political activist.[1] She created the advocacy group Ex-Muslims of North America (EXMNA) which seeks to normalize religious dissent and to help former Muslims leave the religion by linking them to support networks.[2] She is the co-founder and director of development for EXMNA.[3] Haider was born in Karachi, Pakistan , in a practicing
  • 1.3K
  • 28 Nov 2022
Topic Review
Chitosan
Chitosan is a random copolymer comprising d-glucosamine (the deacetylated ones) and N-acetyl-d-glucosamine units.
  • 1.3K
  • 12 Apr 2021
Topic Review
Veterinarians as Animal Welfare Experts
Veterinarians are animal health experts, and they have been conferred a leading role as experts in animal welfare. This expectation of veterinarians as welfare experts appears to stem from their training in veterinary medicine as well as professional contributions to welfare-relevant policy and law. Veterinarians are ideally situated to act as animal welfare experts by virtue of their core work with animals and potential influence over owners, their roles in policy development, compliance, and monitoring, and as educators of future veterinarians.
  • 1.3K
  • 17 Dec 2021
Topic Review
Protein Kinase
Protein kinases (PKs) are enzymes that catalyze the transfer of the terminal phosphate group from ATP to a protein acceptor, mainly to serine, threonine, and tyrosine residues.
  • 1.3K
  • 15 Jan 2021
Topic Review
Medicinal Plants against SARS-CoV
SARS-CoV-2 infection (COVID-19) is in focus over all known human diseases, because it is destroying the world economy and social life, with increased mortality rate each day. To date, there is no specific medicine or vaccine available against this pandemic disease. However, the presence of medicinal plants and their bioactive molecules with antiviral properties might also be a successful strategy in order to develop therapeutic agents against SARS-CoV-2 infection. The identification of novel antiviral compounds is of critical significance, and medicinal plant based natural compounds are a good source for such discoveries. In depth search and analysis revealed several medicinal plants with excellent efficacy against SARS-CoV-1 and MERS-CoV, which are well-known to act on ACE-2 receptor, 3CLpro and other viral protein targets. It has consolidated the data of several medicinal plants and their natural bioactive metabolites, which have promising antiviral activities against coronaviruses with detailed modes of action/mechanism. It is concluded that this topics will be useful for researchers worldwide and highly recommended for the development of naturally safe and effective therapeutic drugs/agents against SARS-CoV-2 infection, which might be used in therapeutic protocols alone or in combination with chemically synthetized drugs.
  • 1.3K
  • 01 Dec 2020
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