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Topic Review
Triticum aestivum L.
Common wheat (Triticum aestivum), one of the world’s most consumed cereal grains, is known for its uses in baking and cooking in addition to its medicinal uses. As this plant’s medical benefits are enormous and scattered, the pharmacological activities were focused, phytochemistry, and the nutritional values of Triticum aestivum. It is a good source of dietary fiber, resistant starch, phenolic acids, alkylresorcinols, lignans, and diverse antioxidant compounds such as carotenoids, tocopherols and tocotrienols. These constituents provide Triticum aestivum with a wide range of pharmacological properties, including anticancer, antimicrobial, antidiabetic, hypolipemic, antioxidant, laxative, and moisturizing effects.
  • 1.3K
  • 05 Jul 2022
Topic Review
Duck
Duck is the common name for numerous species in the waterfowl family Anatidae which also includes swans and geese. Ducks are divided among several subfamilies in the family Anatidae; they do not represent a monophyletic group (the group of all descendants of a single common ancestral species) but a form taxon, since swans and geese are not considered ducks. Ducks are mostly aquatic birds, mostly smaller than the swans and geese, and may be found in both fresh water and sea water. Ducks are sometimes confused with several types of unrelated water birds with similar forms, such as loons or divers, grebes, gallinules and coots.
  • 1.3K
  • 18 Oct 2022
Topic Review
Ribonucleotides in DNA
RNA is frequently found into DNA. Single embedded ribonucleotides are mainly introduced by DNA polymerases. Longer stretches of RNA can also anneal to DNA, forming RNA:DNA hybrids, as occurs for R-loops. Even if R-loops are the most studied hybrid structures, the world of RNA:DNA hybrids is much wider. Polyribonucleotide chains are indeed synthesized to allow Okazaki fragments priming in the process of DNA replication, and double-strand breaks repair and may also result from the direct incorporation of several consecutive ribonucleotides by DNA polymerases. We discuss about all the possible sources of single and multiple ribonucleotides in DNA, focusing on situations where the aberrant processing of RNA:DNA hybrids may result in potentially harmful stretches of consecutive ribonucleotides embedded into the genome, whose existence is also supported by their presence into the DNA of organelles.
  • 1.3K
  • 01 Nov 2020
Biography
David Abram
David Abram (born June 24, 1957) is an American philosopher, cultural ecologist, and performance artist, best known for his work bridging the philosophical tradition of phenomenology with environmental and ecological issues.[1][2] He is the author of Becoming Animal: An Earthly Cosmology[3] (2010) and The Spell of the Sensuous: Perception and Language in a More-than-Human World (1996), for which
  • 1.3K
  • 12 Dec 2022
Topic Review
Legume Protease Inhibitors as Biopesticides
Legumes can produce many different molecules in response to the attack of insects, nematodes, molds, bacteria, and viruses. Protease inhibitors (PIs) are proteins produced by legumes that inhibit proteolytic enzymes of phytopathogens, which cannot feed on the amino acids of the plant. Legume’s strategy to avoid phytopathogens can be used to produce biopesticides and eliminate or decrease the use of agrochemicals in agriculture.
  • 1.3K
  • 06 Nov 2020
Topic Review
Medical Devices Associated Nosocomial Infections
Healthcare-associated infections (HAIs) are caused by nosocomial pathogens. HAIs have an immense impact not only on developing countries but also on highly developed parts of world. They are predominantly device-associated infections that are caused by the planktonic form of microorganisms as well as those organized in biofilms. This review elucidates the impact of HAIs, focusing on device-associated infections such as central line-associated bloodstream infection including catheter infection, catheter-associated urinary tract infection, ventilator-associated pneumonia, and surgical site infections associated with their peculiar microorganisms along with conventional and novel therapies.
  • 1.3K
  • 29 Mar 2022
Topic Review
Coronavirus Diseases
At the end of 2019 a novel virus, SARS-Cov-2, causing severe acute respiratory syndrome has expanded from Wuhan, China. In March 2020 the World Health Organization declared the SARS-Cov-2 virus a global pandemic. We performed a narrative review to describe existing literature with regard to COVID-19 epidemiology, pathophysiology, diagnosis, management and future perspective. MEDLINE, EMBASE and Scopus databases were searched for relevant articles.Although only when the pandemic will end it will be possible to assess the health, social and economic impact of this global disaster, this review represents a picture of the current state of the art. In particular, we focus on public health impact, pathophysiology and clinical manifestations, diagnosis, case management, emergency response and preparedness.
  • 1.3K
  • 07 May 2021
Topic Review
Polyphenols and omega-3 as nutriceuticals
The adequate combination of the well-recognized individual nutraceutical properties of polyphenols and omega-3 polyunsaturated fatty acids from fish oils (eicosapentaenoic and docosahexaenoic acids), particularlly their single antioxidant and anti-inflammatory properties, may offer a powerful tool for the design of successfully nutritional interventions for the prevention and palliation of a plethora of human diseases, often diet-related, whose etiology and progression are characterized by redox homeostasis disturbances and a low-grade of chronic inflammation. However, the certain mechanisms behind their biological activities, in vivo interaction (both between them and other food compounds), and their optimal doses and consumption are not well-known yet. Therefore, we review here the recent accumulated evidence in both preclinical and clinical trials, of the cooperative action between polyphenols and fish oils as nutraceuticals on human health, focusing on the mechanisms and pathways described and the effects reported. The final objective is to provide useful information for developing effective strategies of personalized nutrition based on the combined used of these bioactive food compounds.
  • 1.3K
  • 11 Jul 2021
Topic Review
Colorectal Cancer Cells
The majority of deaths related to colorectal cancer (CRC) are associated with the metastatic process. Alternative therapeutic strategies, such as traditional folk remedies, deserve attention for their potential ability to attenuate the invasiveness of CRC cells. The aim of this study is to investigate the biological activity of brown Cuban propolis (CP) and its main component nemorosone (NEM) and to describe the molecular mechanism(s) by which they inhibit proliferation and metastatic potential of 2 CRC cell lines. CP and NEM significantly decreased cell viability and inhibited clonogenic capacity of CRC cells in a dose and time-dependent manner, by arresting the cell cycle in the G0/G1 phase and inducing apoptosis. Furthermore, CP and NEM downregulated BCL2 gene expression and upregulated the expression of the proapoptotic genes TP53 and BAX, with a consequent activation of caspase 3/7. They also attenuated cell migration and invasion by inhibiting MMP9 activity, increasing E-cadherin and decreasing β-catenin and vimentin expression, proteins involved in the epithelial–mesenchymal transition (EMT). NEM, besides displaying antiproliferative activity on CRC cells, is able to decrease their metastatic potential by modulating EMT-related molecules. These findings provide new insights about the antitumoral properties of CP, due to NEM content.  
  • 1.3K
  • 01 Nov 2020
Biography
Arthur B. C. Walker Jr.
Arthur Bertram Cuthbert Walker Jr. (August 24, 1936 – April 29, 2001) was a solar physicist and a pioneer of EUV/XUV optics. He is most noted for having developed normal incidence multilayer XUV telescopes to photograph the solar corona. Two of his sounding rocket payloads, the Stanford/MSFC Rocket Spectroheliograph Experiment and the Multi-Spectral Solar Telescope Array, recorded the first fu
  • 1.3K
  • 08 Dec 2022
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